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Biomedical subjects

M G Damber

Publications and source records attributed to M G Damber.

47 records · Page 3Linked to original sources
PubMed1976

A quantitative study of the pregnancy zone protein in sera of woman taking oral contraceptives.

By means of a single radial immunodiffusion the concentration of "the pregnancy zone protein" (PZ) was measured in sera from women taking oral contraceptive drugs. Woman taking only 0.3 mg. of norethisterone were found not to induce measurable amounts of PZ, whereas women taking combined contraceptive drugs showed a significant rise in concentration of PZ. After six months' treatment, 1 mg. of norethisterone and 0.1 mg. of meastranol daily were found to give an average concentration of PZ amounting to 59 mg. per 100 ml., that is, approximately half of the concentration of PZ in sera from women during the last trimester of pregnancy. Different combined contraceptive pills gave rise to different concentrations of PZ.

Contraceptives, Oral↗
PubMed1976

Serum naphythylamidase isoenzymes during hormonal treatment. Electrophoretic and quantitative studies.

Alterations in serum naphthylamidase isoenzymes were studied by electrophoretic and quantitative methods in women treated with oral contraceptives and women treated with naturally occurring conjugated estrogens for climacteric symptoms. In women treated with oral contraceptives the appearance of extra isoenzyme components was accompanied by a distinct and significant increase in the total serum naphthylamidase activity, whereas in treatment with conjugated estrogens no such increase was found. The result suggests that combined oral contraceptives and natural estrogens affect the serum naphthylamidase pattern in different ways.

Adult↗
PubMed1976

Induction of the "pregnancy zone" protein by conjugated oestrogens.

Treatment with conjugated oestrogens was found to increase significantly the serum concentration of the pregnancy zone protein (PZ) in a group of postmenopausal women. The basic level of PZ before treatment was comparatively high in this group of women and might be related to age and previous pregnancies. Naturally occurring conjugated oestrogens have a similar effect on the induction of PZ as synthetic oestrogens.

Estrogens, Conjugated (USP)↗