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Biomedical subjects

M Fulton

Publications and source records attributed to M Fulton.

At least 55 records · Page 3Linked to original sources

Phonocardiographic and echocardiographic features of Lillehei-Kaster mitral prosthesis.

Fifteen patients were studied with phonocardiography (phono) and echocardiography (echo) three to 13 months after mitral valve replacement with Lillehei-Kaster mitral valve prostheses. Echo measurements in all patients included prosthesis excursion (DE), opening velocity (OV), closing velocity (CV), and Q-to-mitral prosthesis closure (Q-MPC). In five patients, further, echo measurements included isometric contraction period (ICP), left ventricular ejection time (LVET), and time to completion of aortic valve opening (TCAO). Phono measurements in all patients included pre-ejection period (PEP), LVET, and PEP/LVET. Further phono measurements in the same five patients in whom further echo measurements were performed included Q to first heart sound (Q-S1), ICP, and isometric relaxation period (IRP). Phono and echo measurements were done sequentially. The echo results showed widespread values for DE, OV and CV with no correlation between clinical state, size of prosthesis, or postoperation duration. There was a positive correlation between CV and OV, r + 0.65. Q-MPC by echo averaged 72 msec, which is longer than reported values for Q-to-mitral valve closure in normal people. Similarly, ICP by echo was shorter than ICP by phono in every patient. Of the phono measurements IRP was shortest (45 msec) in one patient in congestive heart failure with a possible prosthesis malfunction. We conclude that echo- and phonocardiography are useful tools in evaluating mitral prosthesis function, but because normal values are widespread, individual measurements may be useful for followup in the same individual. Precise measurement of subdivisions of systolic intervals are now possible with these techniques.

Adult↗

Prognosis of new and worsening angina pectoris.

The natural history of new and worsening angina pectoris was studied in 251 men aged under 70 years. Most were ambulant and all were referred by selected general practitioners to a special hospital clinic over two and a half years. Heart attacks developed in 39 patients, nine of whom died. Seventy-two per cent of the attacks occurred within six weeks of the onset or worsening of angina. Of the 212 patients who did not suffer myocardial infarction and who were clinically reviewed six months after their first attendance 66 had been pain free for the previous three months and 14 had experienced only infrequent attacks of angina. Of the 128 men aged under 65 years who were previously in employment 81% had returned to full-time work six months after their first attendance. A discriminant function analysis using many variables was made to develop a predictive index that would allow patients with new or worsening angina who were likely to develop serious cardiac complications to be identified. This did not prove possible, and the only predictive factor of significance was an increased cardiothoracic ratio. The syndrome of new and worsening angina has a low risk of early death, and many patients are symptom free six months later. In general, emergency coronary arteriography and surgery is not indicated.

Adult↗