Localized 31P-spectroscopy of the human heart.
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Adenosine Triphosphate↗
Biomedical subjects
M Friedrich
Publications and source records attributed to M Friedrich.
[Manual medical findings in relation to the site of pain in vertebral disorders].
Segmental functional disturbances of the spinal column are important and frequent causes of pain in the locomotor and supporting system. Results of the examination of the clinical function of the vertebral column of 151 patients are compared with the site of pain and possible connexions as well as characteristics are discussed.
Female↗
Localization of hydrolysis and transport of dipeptides in the mucosa of the small intestine (established on the basis of the anoxic criterion).
The influence of anoxia on the hydrolysis and transport of certain dipeptides by the rat small intestine in vitro was investigated. It was shown that in most cases, during anoxia there is virtually complete inhibition of active transport, whereas the hydrolysis of dipeptides, both by the intact intestine and by homogenates of the mucosa, is unchanged. These data suggest an important role of membrane hydrolysis at the concluding stages of peptide digestion in the small intestine. The interrelationship of the two types of peptide hydrolysis: membrane and intracellular, is discussed on the basis of the data obtained.
Aerobiosis↗
[Pregnancy and labor in underweight pregnant patients].
The impact of underweight (Broca-index < 78%) on pregnancy, delivery and puerperium were studied in 104 matched pairs. Match criteria were: age, parity, and height. Underweighed pregnant women were significantly more likely to have an multitude of adverse outcomes, including hypotension (p = 0.0001), anemia (p = 0.02), premature labor (p = 0.0001), premature delivery (p = 0.009), small for gestational age (p = 0.02), hyperbilirubinemia (p = 0.02) and a higher rate of neonatal admission to the intensive care unit (p = 0.03). Underweighed women are at high risk for maternal and perinatal outcome.
Adult↗
[Myocardial revascularization interventions].
UNLABELLED: Elective coronary artery bypass surgery (CABG) can be performed with low operative mortality. There is a controversial discussion whether short- and long-term results of CABG can justify this procedure even in elderly patients. MATERIAL AND METHODS: We retrospectively evaluated the clinical profile, operative procedure, postoperative short- and long-term results of 1127 patients over 70 years of age who underwent myocardial revascularization between January 1985 and December 1996. RESULTS: Mean age was 73.9 years. In 1996, septuagenarians represented 21.5% of our operated coronary patients, when compared with 6.4% in 1985. Analysis of risk factors showed an increasing prevalence of renal failure, obesity, hyperuricemia and a history of smoking. Preoperatively 87% of our patients were in NYHA-class III and IV. The percentage of emergent operations decreased over the observed period by 10.3%. Internal mammary artery was used with increasing frequency (44.8% in 1985-92 vs. 61.5% in 1993-96). The number of simultaneous valve replacements increased, too. Postoperatively, we noted rising incidence of respiratory failure (17.1%) and neurological disorders (13.7%). On the other hand, the need for intraaortic balloon pumping and hemofiltration declined by 6.6% and 2.9%. Perioperative mortality (< or = 24 h) was 3.65%, hospital mortality (< or = 30 days) was 9.64%. Actuarial 1 year at was 82% (+/- 4.3%), and 65.7% (+/- 3.8%) at 5 years. CONCLUSIONS: Our data suggest that CABG can be performed in septuagenarians with an acceptable operative risk. Since the large majority of patients improve symptomatically, surgery is the recommendable option for a growing number of elderly patients suffering from severe angina.
Age Factors↗