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Biomedical subjects

M Franzini

Publications and source records attributed to M Franzini.

41 records · Page 3Linked to original sources
PubMedDate not supplied

[Physiopathology and therapy of foreign bodies in the upper digestive tract].

Fibroendoscopy is the treatment of choice for foreign oesophageal and gastric bodies. Whereas the presence of objects in the oesophagus demands immediate endoscopic removal, gastric localization does not require any emergency treatment except for cases of perforation or incarceration, as most foreign bodies (80-90%) are eliminated naturally. Only two weeks after ingestion, in the case of failed expulsion, is it necessary to proceed to endoscopic removal so as to prevent decubitus or perforation erosions. Endoscopic extraction is made difficult by the length and weight of the object, on by its smallness and lack of texture, which make it hard to get hold of. In the case of suture stitches, it may be hard to cut them because of the presence of a gastric mucosa reactive granulomatous inflammatory process. Contraindications to endoscopic extraction are the failure of the patient to cooperate, acute oesophagitis (peptic and due to caustics) and perforating in the stomach, due to congenital or acquired malformations, means that surgery is necessary. The elimination of foreign bodies depends on the correlation between shape and size of object and the anatomo-functional components of the digestive ways. With reference to an approximate geometric schematization of transit organs, the physiopathology of foreign bodies may be expressed by means of mathematical formulae whose manifold variables sometimes make the natural elimination of the bodies unpredictable.

Adolescent↗
PubMedDate not supplied

[A high-resolution computed tomographic study of the pulmonary interstitium in systemic autoimmune diseases].

This study was aimed at assessing the diagnostic capabilities of radiologic imaging in systemic autoimmune diseases. Forty-one patients (37 women and 4 men, mean age: 57.9 years, range: 37-73) were examined: 17 of them had rheumatoid arthritis, 8 Sjögren's syndrome, 11 progressive systemic sclerosis, 3 systemic lupus erythematosus, 1 mixed connective tissue disease and 1 undifferentiated connective tissue disease. The clinical features were compared with chest X-ray and HRCT findings. Functional lung examination (spirometry) was performed in 30 patients and in 22 of them chest X-ray findings could be compared with HRCT results since the examinations were performed on the same day. Seventeen patients complained of dyspnea (41.4%) and CO diffusion was reduced in 53% of the investigated patients. Chest films showed interstitial changes in 14 of 22 patients (63.6%), while HRCT findings were abnormal in 90.2% of the patients. Significant changes in HRCT patterns were detected only in 7 of the patients complaining of dyspnea (41.1%) and in 5 of the patients with reduced CO diffusion. In conclusion, HRCT proved to be much more sensitive than plain chest films. Dyspnea and functional respiratory tests correlated poorly with HRCT findings.

Adult↗
PubMedDate not supplied

[Urachal cyst. A case report and review of the literature].

The pathology of urachal disease is rarely seen. This article refers to a case of urachal cyst in a twenty-five-year-old male. In order to discuss the pathogenic, clinical and therapeutic aspects of this rare pathology, it is necessary to carry out a complete revision of the literature. Diagnosis is helped by ultrasound and CT scan of the lower abdomen, while fistulography is necessary when there is cutaneous drainage. The treatment consists of surgical approach which includes complete en-bloc excision of the cyst together with possible urachal residue. Such treatment is indispensable in order to avoid acute infection and/or malignant degeneration, frequent complications which are very serious.

Adult↗
PubMedDate not supplied

[Acute obstruction of the abdominal aorta].

The acute occlusion of abdominal aorta is a rare event that may have severe clinical results. Personal experience in three cases of acute thrombosis treated in emergency surgery are presented. Aorto-iliac thromboendarterectomy, aorto-bifemoral bypass and thrombectomy with Fogarty catheter were performed. In the first case, after the operation, a renal ischemia occurred. The second and the third patient died after seven days and twenty-four hours respectively.

Acute Disease↗