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Biomedical subjects

M Fotinou

Publications and source records attributed to M Fotinou.

7 recordsLinked to original sources
PubMed2005

Microscopic polyangiitis complicated by the development of prostate cancer and flutamide-induced hepatitis.

We report a case of a 65-year-old man with microscopic polyangiitis who developed prostate cancer and gastric adenocarcinoma after prolonged oral use of cyclophosphamide. Acute hepatitis with jaundice and marked increase in aminotranferases occurred after 6 months of flutamide treatment for metastatic prostate carcinoma. It is suggested that patients with vasculitis or other autoimmune disorders should avoid prolonged use of cyclophosphamide and other cytotoxic drugs in order to minimize long-term adverse effects, of which the risk of cancer is by far the most important. In patients on flutamide treatment, careful monitoring of flutamide administration with repeated liver function tests should be undertaken, and the drug must be immediately discontinued in patients with abnormal results to avoid progression of liver injury.

Adenocarcinoma↗
PubMed1997

Multiple cholesterol embolism: a case report.

Cholesterol embolism is an unusual but serious complication of intra-arterial procedure such as arterial catheterization, angiography, and angioplasty. In this short paper a case of fatal cholesterol embolisation after angiography is described. Histology examination revealed atheroembolic lesions in the kidneys, spleen and colon.

Aged↗