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Biomedical subjects

M Flament

Publications and source records attributed to M Flament.

20 records · Page 2Linked to original sources

[Assessment instruments for bulimia].

Systematic assessment of bulimia, alike the clinical definition of the disorder, is still meager and lacks reliability. Development of new evaluation instruments is the focus of many current researches. This article will distinguish: rating scales specific of bulimia, for screening in epidemiological surveys and clinical practice, as well as for measure of the severity of the symptoms; structured interviews for evaluation of bulimic patients, for clinical and research use; eating disorders rating scales, already used for anorexia nervosa; other rating scales of interest with bulimic patients; and more possible evaluation methods. Finally, we will review assessment measures for use in treatment studies of bulimia.

Bulimia↗

[Pharmacologic treatment of bulimia].

The rationale for pharmacological treatment of bulimia nervosa is summarized and a review of controlled therapeutic trials shows contradictory results. A number of antidepressant agents (tricyclics: imipramine, desipramine, amitriptyline; IMAO: phenelzine, isocarboxazide; trazodone; fluoxetine) appear more effective than placebo in double-blind controlled trials of 6 to 16 weeks. In similar studies, other antidepressants (mianserine, fluvoxamine) are ineffective. Improvement reported is often incomplete and the low percentage of patients totally abstinent at the end of treatment appears of poor pronostic value for long-term outcome. Methodological limitations of existing studies are discussed, and some psychopathological factors to consider in the assessment of therapeutic response are proposed.

Antidepressive Agents↗