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Biomedical subjects

M Feinsod

Publications and source records attributed to M Feinsod.

At least 109 records · Page 6Linked to original sources
PubMed1981

Persistent nonketotic hyperglycemia as a grave prognostic sign in head-injured patients.

The authors studied 86 consecutive patients admitted to the ICU after severe head trauma. Of these, 19 nondiabetic patients developed persistent nonketotic hyperglycemia (NKH), defined as plasma glucose greater than 270 mg/dl (15 mM/L), 1.7 +/- 1.1 (SD) days after injury. When NKH occurred, all patients were in very deep coma (Glasgow Coma Scale score 3), and when intracranial pressure (ICP) was measured (12 patients), its mean value was 59.8 +/- 20.4 mm Hg. Although 11 of 19 patients had associated diabetes insipidus (DI), NKH was not related to increased fluid and glucose loading. All patients with NKH died (mean time of survival after NKH was 2.1 +/- 1.4 days) in contrast to a 17.1% early mortality rate in patients with severe head injury without NKH. The authors could not show a direct correlation between the height of ICP and the level of blood glucose.

Adolescent↗
PubMed1980

Choroid plexus papilloma: hydrocephalus and cerebrospinal fluid dynamics.

Dynamics of the cerebrospinal fluid were measured pre- and postoperatively in a patient with a choroid plexus papilloma associated with hydrocephalus. The production rate was 0.35 ml/min, absorption 0.0057 ml/min H2O, and the critical opening pressure 196 mm H2O. Following removal of the tumor, these values were 0.32 ml/min, 0.0053 ml/min/mm H2O, and 105 mm H2O, respectively. It was concluded that no over-production of cerebrospinal fluid was present in this case. The hydrocephalus was due solely to obstruction of the fourth ventricle.

Adult↗
PubMed1979

Pseudostereoscopic illusion caused by interhemispheric temporal disparity: clinical and experimental observations.

An extension of Pulfrich's pseudostereoscopic illusion to a situation without interocular disparity, ie, even under purely monocular circumstances, was clinically observed and experimentally produced. The perceived distortion of the movement of a swinging pendulum was found to depend on different combinations of interhemispheric disparity induced by selective prolongation of the conduction time from the nasal or temporal retina to the corresponding hemisphere. In patients, tumor pressure caused the slower conduction time. In normal subjects, neutral density filters covering different visual fields produced similar conduction delays under experimental conditions. Recording the visually evoked response from over each hemisphere provided an objective tool for demonstration and measurement of interhemispheric differences of retinocortical conduction times in various clinical and experimental setups.

Adult↗
PubMed1978

Bilateral transverse sinus obstruction in benign intracranial hypertension due to hypervitaminosis A.

Hypervitaminosis A may be associated with benign intracranial hypertension. So far, the explanation for this phenomenon has remained obscure. A 17-year-old patient with benign intracranial hypertension, following chronic vitamin A intake of 150,000 units daily for acne vulgaris, is presented. Bilateral papilledema was present and bilateral obstruction of the transverse sinuses was demonstrated in the late venous phase of cerebral angiography. Discontinuation of vitamin A and acetazolamide treatment was followed by complete regression of the signs and symptoms of intracranial hypertension. Bilateral sinus obstruction with interference of cerebral sinus outflow is suggested as a critical factor in the pathogenesis of benign intracranial hypertension in vitamin A intoxication. Menstrual dysfunction and tetracycline therapy cannot be completely excluded as possible causative factors.

Acne Vulgaris↗
PubMed1977

Nasopharyngeal tumor initially manifested as myofascial pain dysfunction syndrome.

A patient with facial pain of 1 1/2 years' duration, associated with limitation of opening of the mouth, click, and osteodegenerative changes of the temporomandibular joint, was initially thought to be suffering from a myofascial pain dysfunction syndrome. At first, the patient reacted favorably to muscle exercises and an antidepressive drug, but reduced lacrimation and the development of deafness on the affected side led to re-evaluation and a diagnosis of nasopharyngeal tumor. Biopsy confirmed the presence of an adenocarcinoma of the nasopharynx. The variability of symptoms and the diagnostic problems presented by this tumor are discussed.

Carcinoma, Adenoid Cystic↗
PubMed1976

Midbrain corectopia.

Intermittent corectopia was recently observed in a patient with bilateral, rostral midbrain infarction. Results from neuropathologic examination disclosed isolated but intact Edinger-Westphal nuclei. An explanation of midbrain corectopia centered on segmental innervation of the pupil by the Edinger-Westphal nucleus. In the presence of a paralyzed dilator muscle, select, central inhibition of sphincter tone resulted in an oval and eccentric pupil.

Adult↗
PubMed1976

Visually evoked response. Use in neurologic evaluation of posttraumatic subjective visual complaints.

Evaluation of subjective visual complaints unassociated with objective signs is a frequent problem in neurologic and ophthalmic practice. The visually evoked response (VER) is an important tool for separating the functional from the organic in patients claiming visual disturbance. In visual complaints associated with late posttraumatic epileptic activity, the VER can demonstrate an abnormality even in asymptomatic intervals. In complaints due to concussion, it demonstrates disorganized evoked responses initially and later a return of the normal resonse. It shows an abnormality in the occipital lobes during and after transient compression of the vertebral artery. A normal VER excludes all but trivial involvement of the visual system, symptomatic claims of the patient notwithstanding.

Adult↗
PubMed1976

Malignant evolution of childhood chiasmal pilocytic astrocytoma.

A 27-year-old obese mentally retarded woman showed progression of antisocial behavior with periodic somnolence 18 years after biopsy and irradiation of a large pilocytic astrocytoma of the chiasm and adjacent structures. Visual function, although impaired, had not changed during the long period of postoperative observation. Before she died, the tumor showed angiographic and histologic features of malignant glioma, but neuroradiologic and neuropathologic studies did not establish conclusively that it involved new areas of the brain. This report documents a rare case in which an irradiated childhood optic glioma underwent delayed malignant evolution.

Adult↗
PubMed1976

Monitoring optic nerve function during craniotomy.

During surgical removal of a pituitary adenoma, conduction in the anterior visual pathways was monitored by continuous recording of visual evoked responses (VER). The method employed a scleral contact lens with an embedded flashing diode for delivery of visual stimuli. Evoked potentials of nearly normal latency, amplitude, and form were recorded from occipital scalp electrodes immediately after the optic nerves were decompressed. Restoration of the VER was correlated with restoration of normal vision.

Adenoma↗
PubMed1976

Monitoring of visual function during parasellar surgery.

Damage to the visual system is an unfortunate complication of surgery in the area of the optic chiasm. It is now possible tomonitor the functional status of the visual system intreoperatively at regulat intervals. This is accomplished by recording the Visual Evoked Response to flashes of light from light-emitting-eiodes. These diodes are embedded in a special plastic shell which inserts under the eye lids of each eye. Since the light comes from the diodes in the plastic shell, there is no need to disturb the surgical procedure when a test run is desired. A record is obtained by averaging 100 three-per-second flashes.

Adenoma, Acidophil↗
PubMed1975

Subclinical optic neuropathy in multiple sclerosis. How early VER components reflect axon loss and conduction defects in optic pathways.

The pathological effect of multiple sclerosis in the visual pathways consists of axonal demyelination and axonal loss. These two consequences of the disease, even in its subclinical stages, are reflected in changes in the initial component of the visual evoked response (VER) affecting its latency, configuration, or both. These abnormal early components of the VER were recorded in 25 patients with multiple sclerosis, only 10 of whom had any indication of visual involvement that could be documented historically or by conventional ophthalmic investigation.

Evoked Potentials↗