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Biomedical subjects

M Feingold

Publications and source records attributed to M Feingold.

At least 127 records · Page 7Linked to original sources
PubMed1985

Positive correlation between mature amniotic fluid optical density readings and the absence of neonatal hyaline membrane disease.

Fetal pulmonary maturity is generally determined by analyzing amniotic fluid for surfactants. This task is accomplished by lipid extraction of the fluid and resolution, identification and quantitation of the isolated lipids with thin-layer chromatography. These methods are lengthy, cumbersome and often not available on demand. A quick, simple, reliable and economical test therefore would be highly desirable. We have been able to correlate an optical density (OD) reading of amniotic fluid at 650 nm greater than or equal to 0.15 with the absence of hyaline membrane disease (HMD). For 428 fluids in which an OD reading of greater than or equal to 0.15 was found and delivery occurred within 48 hours, HMD was present in only two infants. The accuracy of the test was 99.53% , with a false-positive rate of 0.47%. With the use of this simple and accurate test one can satisfy the requirement of an on-demand test to determine fetal pulmonary maturity.

Amniotic Fluid↗
PubMed1984

Completely cartilaginous trachea in a child with Crouzon syndrome.

We describe a patient with Crouzon syndrome and congenital tracheal stenosis. The trachea lacked rings and was completely cartilaginous, making it rigid and narrow. The respiratory difficulties that are present in patients with Crouzon syndrome have been ascribed to the nasal or choanal defects that are associated with this condition. However, the presence of congenital tracheobronchial abnormalities as a cause of respiratory problems has not been widely investigated. Congenital tracheal stenosis may occur as an isolated defect or as one of many other congenital defects. In patients with Crouzon syndrome who have recurrent respiratory problems, congenital tracheal or bronchial defects should be considered since surgical intervention may correct the defect.

Abnormalities, Multiple↗
PubMed1984

Detection of cervical incompetence by ultrasound.

Ultrasonography was used to measure the width of the internal os in 96 pregnant women, of whom 43 were considered to have cervical incompetence and were scheduled for cerclage. The remainder of the women were divided into two control groups: (a) 28 women with a normal obstetric history, and (b) 25 women with a history of either previous abortion or traumatic delivery. The mean width of the internal os in the three groups was 25.9 mm +/- 3.7, 15.8 mm +/- 2.7, and 18.2 mm +/- 6.5 respectively; statistically, significant difference were seen between the first group and each of the control groups. All the women in the first control group gave birth successfully at term; of those in the second control group, 5 presented with premature rupture of the membranes. The mean cervical os width in these 5 women was 29 mm, as compared with a mean of 18.2 mm for this group as a whole. We suggest that ultrasonic measurement of the internal os during pregnancy can be a useful and objective new method for the diagnosis of cervical incompetence.

Cervix Uteri↗