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Biomedical subjects

M Farmand

Publications and source records attributed to M Farmand.

At least 19 recordsLinked to original sources

A new therapeutic concept for the treatment of cystic hygroma.

A new therapeutic concept for the treatment of cystic lymphangioma (cystic hygroma) is presented. It consists of intralesional injection of triamcinolone (10 mg/kg) and surgical excision at a second stage if necessary. Four cases are presented to demonstrate the clinical application of this new therapeutic modality. Only in one case it was necessary to perform surgical excision as a second stage procedure, whereas three cases were successfully managed by intralesional injection of triamcinolone alone.

Child, Preschool

[Experiences with the 3-D miniplate osteosynthesis in mandibular fractures].

A geometrically closed quadrangular plate secured with bone screws creates stability in three dimensions. The smallest structural component of a 3-D-plate is an open cube or a square stone. Our clinical results and biomechanical investigations have shown a good stability of the 3-D-plates in the osteosynthesis of mandibular fractures without major complications. The thin 1.0 mm connecting arms of the plate allow easy adaptation to the bone without distortion. The free areas between the arms permit good blood supply to the bone.

Biomechanical Phenomena

[The diagnosis and treatment of congenital facial asymmetries in childhood. A clinical study].

Following a brief discussion of etiology, pathogenesis, and diagnosis of congenital facial asymmetries, a new interdisciplinary treatment concept encompassing the disciplines of orthodontics, maxillo-facial surgery, and pedaudiology is set forth. This concept calls for the surgical reconstruction of the mandibular ramus and of the temporo-mandibular joint already in childhood in those cases in which functional jaw orthopedics has already begun at an early age. Thereafter the occlusal plane can be corrected orthodontically. Six patients were treated according to this concept. Two years nine months after surgery favorable results were observed in relation to occlusion and mandibular growth. Because, however, long term results are still outstanding, the results obtained until now and the treatment concept remain the subject of ongoing critical study.

Child

[Reconstruction of the lateral face in children].

Unilateral hypoplasia in the middle and lower face has different etiological causes. A standardized interdisciplinary treatment of children is demonstrated with the help of ten operated cases and nine children in observation. Depending on the missing structure of the anatomical regions the areas are reconstructed. A pre- and postoperative orthodontic treatment is part of the concept. With an operative intervention in childhood, it is possible to gain in most cases a more normal appearance till adulthood.

Adolescent

[Reconstruction of the orbital walls by autologous calvarial transplants].

This article reports on the experience gained with outer table calvarial bone grafts used for the reconstruction of the bony orbital walls in 43 patients. The transplants were harvested in the parietal area above the non-dominant hemisphere. Morbidity and complication rate at the harvest site were extremely low. In all patients the grafts became uneventfully incorporated.

Bone Transplantation

[Fracture healing of the ethmoid bone--a contribution to rhinologic management of naso-ethmoid injuries].

Severe maxillofacial trauma accompanied by a dislocated ethmoidal bone fracture was confirmed by CT imaging in 15 adult patients. Routine surgical management included reduction of fractures, miniplate fixation and/or intermaxillary fixation with interosseous wiring. The fractured ethmoidal cell system was left to heal spontaneously. A follow-up examination including endoscopy of the nasal cavity as well as active anterior rhinomanometry and computed tomography was carried out approximately 24 months after surgery. The fractured ethmoidal cell system showed a clear tendency to spontaneously reventilate and drain. However, in 8 of 30 sides a traumatic obstruction of the anterior ethmoid led to secondary frontal sinus mucositis. 12 out of 30 maxillary sinuses ranged from marked mucosal swelling to the development of a traumatic mucocele. Altogether, 9 of the 15 patients suffered from paranasal sinusitis. Routine debridement of every fractured ethmoidal cell system does not appear to be necessary. In case of fractures of the anterior ethmoid with probable obstruction of the nasofrontal duct and/or maxillary sinus ostium, endonasal endoscopic surgery is recommended for minimally invasive reconstruction of the ventilation and drainage of the frontal and maxillary sinus during primary surgical management. Furthermore, patients with severe naso-orbito-ethmoidal fractures should undergo rhinological follow-up examination including CT-imaging approximately 3 months after surgery.

Adolescent

Recurrence of a solitary bone cyst of the mandibular condyle in a bone graft. A case report.

The recurrence of a solitary bone cyst of the mandibular condyle in a costochondral bone graft is reported. A solitary bone cyst of the right condylar head and neck of a 10-year-old boy was treated by total resection and immediate reconstruction with a costochondral bone graft. Two years after the first operation, a recurrence of the solitary bone cyst within the bone graft was noted. An open treatment was performed. A review of the literature on solitary bone cysts and recurrences of solitary bone cysts shows that the case reported is unique. Possible reasons for the recurrence are discussed.

Bone Transplantation

The treatment of the fractured edentulous maxilla.

The results of a follow-up of 13 out of 21 patients treated for fractures of the edentulous maxilla are presented. They were treated alternatively with craniofacial suspension wiring and with miniplate osteosynthesis. Better results are achieved by miniplate osteosynthesis. Depending on the general condition of the patient, a treatment scheme can be recommended.

Adult

[Pathological changes in face and skull in acromegaly].

31 patients (mean age 52.7 years) suffering from persistent symptoms of a growth hormone producing pituitary adenoma underwent both clinical and roentgenological examinations. The results of standardized x-ray analysis of the viscero- and neurocranium were compared with those of a group of 25 healthy subjects (mean age 42.1 years): Although several remarkable changes were observed, statistically significant changes of the facial skeleton could be found only in the lower jaw. The main contribution to its elongation was given by the chin prominence and the condyle. The findings in the neurocranium could be divided in symptoms of first and symptoms of second choice. With the help of these parameters, a score was established to facilitate interpretation of early signs of acromegaly in lateral skull radiographs. Two clinical symptoms found in our patient sample have not been mentioned before in literature about acromegaly: the so-called "hanging columella" and marked changes in diameter of the canalis mandibularis.

Acromegaly

[The value of 3-dimensional plates in maxillofacial surgery].

Plate osteosynthesis for bone fragment stabilisation in maxillo-facial surgery is a universal method whose advantages and drawbacks are now well documented. A new system of plates made out of titanium (3-D plates) is presented. The geometry of the plate assures a good stability in the three dimensions of the space. Easy use, good resistance against torque forces, compact form of the plate are some of the advantages. Various clinical cases are presented.

Adult

Typical changes in the viscerocranium in acromegaly.

31 patients (mean age 52.7 years) suffering from persistent symptoms of a growth hormone-producing pituitary adenoma underwent both clinical and radiological examination at least one year after transnasal extirpation of the tumour. The results of standardized X-ray analysis of the viscerocranium were compared with a group of 21 healthy subjects (mean age 42.1 years): Although several remarkable changes of the facial skeleton were observed, statistically significant changes could be found in the lower jaw only. The ascending ramus as well as the mandibular body were found to be elongated. The main contribution to the elongation was made by the chin prominence and the condyle. Two different growth patterns of the mandible could be determined; neither of them was pathognomonic for acromegaly. Due to overgrowth of the septal cartilage in 7 patients we found a so-called "hanging columella". In 16 patients the mandibular canal was widened and showed marked deviations in its diameter or a funnel-shaped mandibular foramen.

Acromegaly

[Interstitial and percutaneous radiotherapy after limited surgery in carcinoma of the oral cavity].

From 1.1. 1986 to 31.12. 1990 50 patients with epidermoid carcinoma of the floor of the mouth and the mobile tongue (stage T1 18, stage T2 20, stage T3 eight and stage T4 four patients) were treated by surgery, 192-iridium implantation using the plastic tube technique and percutaneous irradiation. Surgery was performed as enoral resection (35 patients) or en bloc tumour resection with part of the mandible and flap reconstruction (15 patients). Interstitial therapy was considered as a boost to primary tumour region, the dose given ranged between 16 and 33 Gy. 50 to 60 Gy were applied with external beam radiotherapy. Management of the neck consisted of elective or radical neck dissection followed by external beam radiotherapy (50 to 60 Gy). At 2/1991 median follow-up was 17 (three to 53) months. 35 patients are alive and tumour-free, one patient lives with tumour. 14 patients died, eight patients tumour-related, four patients of intercurrent disease and two patients because of a second primary. Primary local control was 18/18 patients for stage T1, 19/20 patients for stage T2, 7/8 patients T3, 3/4 patients for stage T4. Three patients suffered from nodal recurrences, four patients from distant metastases. Complication rate was acceptable. Soft tissue necrosis occurred in 4/18 patients (T1); 5/20 patients (T2); 3/8 patients (T3) and 1/4 patients (T4). Three patients developed osteoradionecrosis. Our results show that combined modality treatment for tumours of the oral cavity yields high local control with acceptable complication rate.

Adult