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Biomedical subjects

M Fall

Publications and source records attributed to M Fall.

225 records · Page 13Linked to original sources

[Empyema caused by Staphylococcus aureus in children: the experience of the Albert Royer Children's Hospital at Fann University Hospital, Dakar].

We report a retrospective study of 58 cases of empyema caused by Staphylococcus aureus at the Albert Royer Children's Hospital at the Fann University Hospital, between January 1st 1992 and December 31st 1995. Staphylococcus aureus is the principal bacterium responsible for pleural effusions in children (54%), way ahead of Streptococcus pneumoniae (19%). Most of the children affected (86%) are less than 30 months old. Theses infections are often serious due to the resistance of the bacterium to the usual antibiotics, the lack of solid research data and mechanical complications associated with the effusion. Treatment is based on the use of an appropriate bactericidal antibiotic treatment and pleural drainage.

Age Factors↗

[Hemoglobin C -- beta-thalassemia disease and homozygous beta-thalassemia in a black African family (author's transl)].

The study of a Malian family has allowed to prove existence of two types of beta-thalassemia genes: the beta0 gene which suppresses the synthesis of the beta chain into cis position and the beta+ gene which slows down only partially this synthesis. The difference between this two genes has been possible owing to the hemoglobin C found in this family and induced by the betaC mutated gene. The segregation of the four genes betaA, betaC, beta0 thal, and beta+ thal. has allowed to compare all the possible phenotypes deriving from the combinations by two of these allelic genes.

Alleles↗

[Bacterial meningitis in a pediatric hospital in a tropical zone].

Purulent bacterial meningitides are a very important pediatric problem in tropical areas. From February 1983 to February 1988, 409 cerebrospinal fluid samples from children with purulent meningitides, aged under 15 years, admitted to the Pediatric Hospital Albert Royer, Dakar, were examined for the presence of bacterial agents. In 222 (54.2%) samples, one bacterial agent or soluble antigens were detected. Among these, 3 bacterial agents were most frequently identified: 94 (42.3%) Haemophilus influenzae, 71 (31.9%) Streptococcus pneumoniae and 25 (11.2%) Neisseria meningitidis. The increase in bacterial meningitides observed during cool and dry seasons was essentially due to Haemophilus influenzae and Streptococcus pneumoniae. The bacterial strains were found to be susceptible to antibiotics usually administered. However, almost 22% of Haemophilus influenzae strains were resistant to ampicillin or chloramphenicol. A high mortality (33%) was observed, especially with Streptococcus pneumoniae. The purulent bacterial meningitides are a most important pediatric problem in tropical areas.

Adolescent↗

Mycoplasma hominis and interstitial cystitis.

Antibodies to Mycoplasma hominis were detected by indirect hemagglutination in nine (56%) of 16 patients with chronic interstitial cystitis. In seven patients (44%), titers of greater than or equal to 160 were found. Antibodies to Ureaplasma urealyticum were detected in three (19%) of these patients; in only one patient was a high titer, i.e., greater than or equal to 160, found. M. hominis was isolated from voided urine of two patients, and U. urealyticum was recovered from the urine of three patients. A similar incidence of antibodies to M. hominis was found in 20 age- and sex-matched women treated transurethrally for bladder tumors. The high incidence of indirect hemagglutination antibodies to M. hominis found in these two groups of urologic patients who were subjected to repeated instrumentation of the urinary tract remains unexplained.

Adult↗

[Care charges and direct costs related to hospitalization of Senegalese children with cerebral malaria. Study of 76 cases in the Albert-Royer Hospital in Dakar in 1991-1992].

To optimize the funds devoted to health care, and to objectively assess the tools used in monitoring patients with cerebral malaria, we determined two parameters, care charges and direct costs due to hospitalization. During this longitudinal study conducted at the Albert Royer Pediatric Hospital in Dakar from October 15, 1991 to October 15, 1992 with 76 cases, malaria represented 5.2% of the febrile cases and 3.4% of the hospitalized cases. The lethality rate was 3.4%. Clinical features were not correlated with care charges and thus were not good indicators of worker's labor. The average cost of a cerebral malaria hospitalization was estimated at 35,710 F CFA (In October 1992, 1 F CFA = 0.02 FF). This cost is very high depending the limited resources of the region. Rapid and proper treatment of malaria cases may lead to a significant reduction of costs.

Adolescent↗