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Biomedical subjects

M F Vazquez

Publications and source records attributed to M F Vazquez.

22 records · Page 2Linked to original sources

Invasive papillary carcinoma of the breast: mammographic appearance.

The mammographic findings in 18 patients with invasive papillary carcinoma were studied retrospectively. The mammograms of 10 patients showed a multinodular pattern, and seven patients had solitary nodules. One patient had an irregular, ill-defined mass in the retroareolar region. Two patients were found to have carcinoma in the contralateral breast, and two patients had intraductal carcinoma adjacent to the invasive papillary carcinoma. The varied mammographic features that may occur with this rare breast malignancy are discussed.

Aged↗

Comparison of fine-needle aspiration and frozen section of palpable mammary lesions.

We compared the results of 100 consecutive fine-needle aspirations of palpable mammary lesions in women with 100 consecutive frozen sections done on palpable suspicious nodules in the breasts of women who had had no prior aspiration. There were no false positive results in either group. The false negative rate of aspirations was 6%, compared with none for frozen section, suspicious cases excluded. In four of six patients with false negative aspirations, the specimen was nondiagnostic or unsatisfactory. (In this series, no repeat aspirations were performed for nondiagnostic or negative specimens, even when clinically suspicious.) We conclude that aspiration of a palpable mammary tumor is a definitive procedure with results equivalent to frozen section and equally suitable for choosing and undertaking definitive therapy, when positive. Negative results, viewed in an appropriate clinical context, also proved conclusive. Atypical or suspicious results at aspiration must be followed by repeat aspiration or excision, since these frequently prove positive; likewise, unsatisfactory or nonrepresentative aspirations must be investigated further, as indicated by the clinical evaluation.

Adult↗

Differentiation of radial scar from scirrhous carcinoma of the breast: mammographic-pathologic correlation.

Radial scar, a sclerosing ductal breast lesion characterized by an irregular stellate pattern of epithelial proliferation around a central fibroelastic core, may be confused histologically with scirrhous carcinoma of the breast. Mammographic features used to distinguish these two entities were found unreliable in a retrospective review of 255 consecutive stellate lesions. Of 73 nonpalpable carcinomas, fourteen (19%) had radiographic features of radial scar. Only the presence of microcalcifications in 11 of those patients helped the authors distinguish carcinoma from radial scars. Four of nine biopsy-proved radial scars had a dense central region, simulating the appearance of scirrhous carcinoma. Stellate lesions with radiolucent centers should be considered suggestive of carcinoma, particularly if associated with microcalcifications.

Adenocarcinoma, Scirrhous↗