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Biomedical subjects

M F Mafee

Publications and source records attributed to M F Mafee.

At least 109 records · Page 6Linked to original sources

Computed tomography scanning in the evaluation of ocular motility disorders.

Ocular muscle disturbances (strabismus) are common disorders affecting two to four per cent of the population. Until recently, CT and MRI have not been used extensively in the diagnosis of congenital and acquired conditions causing strabismus. In this article the value of these scanning techniques in terms of more appropriate therapeutic intervention and further insight into the pathophysiology of these conditions is detailed.

Eye Diseases↗

Lacrimal gland and fossa lesions: role of computed tomography.

The lacrimal gland region can be involved in a wide spectrum of orbital pathology, including tumors and inflammatory and lymphoid lesions. This article focuses special attention on benign mixed tumors because of the excellent prognosis for the patient when it is completely excised at first surgery. The appearance of these lesions on CT is detailed in the illustrations of this article, and the findings of experts in the field are presented as well.

Dacryocystitis↗

MRI and CT of sellar and parasellar disorders.

Discussion of the anatomy of the parasellar region focuses on the optic chiasm and its relationship to surrounding structures. CT and MRI are valuable tools in the imaging of these regions. This article provides a brief review of the technique of CT and MRI with visualized anatomic structures of these areas. A closer look at how CT and MRI are used to delineate the different pathologic processes of the sellar and parasellar regions then follows.

Adenoma↗

The role of the neuroradiologist in vascular disorders involving the orbit.

CT and MRI have become imaging techniques of great value in the diagnosis of vascular orbital lesions. Intraorbital vascular lesions, vascular tumors, intracranial aneurysms, carotid cavernous fistulas, and Tolosa-Hunt syndrome are discussed in detail. They illustrate how the accuracy of CT and MRI in evaluating orbital and intracranial masses has focused the role of angiography in exophthalmos and ophthalmoplegia on detection and assessment of those vascular lesions that may require surgical intervention.

Arteriovenous Fistula↗

Uveal melanoma and similar lesions: the role of magnetic resonance imaging and computed tomography.

The uvea provides a suitable substrate for tumor cells because it is the most vascular portion of the eye. Most primary and metastatic ocular neoplasms involve the choroid, with the most common being malignant melanoma. We review the features of uveal melanomas seen on MRI and CT images and evaluate certain neoplastic and non-neoplastic intraocular lesions that may simulate uveal melanomas.

Choroid Hemorrhage↗

MRI of the normal orbit and optic pathway.

In recent years MRI has made increasingly important contributions to the evaluation of the orbit and optic pathway. The unique ability of MRI to demonstrate soft tissue contrast allows exquisite demonstration of anatomic detail. MRI technique and normal anatomy are reviewed. Today, optimal ophthalmologic work-up is often incomplete without the critical input of the radiologist.

Aqueous Humor↗

Optic nerve tumors: role of magnetic resonance imaging and computed tomography.

Localization and pathologic diagnosis of optic nerve tumors have been greatly improved by high resolution computed tomography and magnetic resonance imaging. Radiologic differentiation of the most common tumors of the optic nerve (meningioma and glioma) can be made by using these new imaging modalities. Early diagnosis of optic nerve lesions has resulted in better prognosis and surgical outcome.

Cranial Nerve Neoplasms↗

Retinoblastoma and simulating lesions: role of CT and MR imaging.

Diagnosis of retinoblastoma is one of the most challenging problems of pediatric ophthalmology and radiology. It must be differentiated from numerous simulating lesions. Accurate diagnosis by means of ultrasonography, CT, and MR is essential for prompt treatment and prevention of metastasis. The CT and MR findings in 45 patients are presented in this article in order to evaluate and compare the usefulness of these two imaging techniques in the diagnosis of retinoblastoma.

Calcinosis↗

Persistent hyperplastic primary vitreous (PHPV): role of computed tomography and magnetic resonance.

The diagnosis of PHPV is often made difficult by its extremely broad array of clinical manifestations, its etiologic heterogeneity, and frequently opaque ocular media. The CT and MR findings are discussed in terms of how they can be of use in the differential diagnosis of PHPV. The strengths and weaknesses of each of these diagnostic methods is detailed in regard to patients who present with unilateral leucocoria, microphthalmos, lens opacity, and retinal detachment.

Child↗

Computed tomography of optic nerve colobomas, morning glory anomaly, and colobomatous cyst.

CT scanning can be of great value in evaluating optic nerve colobomas, particularly in clinical situations in which corneal, lenticular, vitreal, or other opacities hinder visualization of the optic disc. Experience with the patients presented here demonstrates that CT scanning is useful in the assessment of the presence and size of classic colobomas, morning glory anomaly, and microphthalmos with cyst. It is also of value in assessing associated ocular defects such as microphthalmos, shallow anterior chamber, and atrophic ciliary body.

Child↗

Dynamic computed tomography and its application to ophthalmology.

In this review of 31 patients, dynamic CT is discussed as a valuable tool in the study of the dynamics of blood flow in patients with unexplained visual problems that may be related to ischemic optic neuropathy. Dynamic CT scans are obtained by rapid-sequence CT imaging during and following a rapid bolus injection of intravenous contrast medium. It demonstrates the initial passage of contrast material through the area of interest, thus giving a true picture of the degree of vascularity and the dynamics of blood flow.

Diagnosis, Differential↗

Chronic otomastoiditis: a conceptual understanding of CT findings.

Inflammation of the middle ear cleft is a disease of great interest from both clinical and radiologic points of view. The attic floor (tympanic diaphragm), the tympanic isthmus, and the aditus ad antrum play important roles in inflammatory processes of the middle ear cleft. The anatomy of the temporal bone at this level was examined by studying microdissections of 250 fresh temporal bones and reviewing over 1,000 high-resolution computed tomography (CT) scans of the temporal bones. The pertinent anatomy is described, and the role of the tympanic diaphragm and isthmus in determining the degree to which middle ear disease may progress is stressed. The appearances on CT scans of chronic otomastoiditis, tympanosclerosis, cholesterol granuloma, attic retraction pocket, and acquired cholesteatoma are reviewed and illustrated.

Adolescent↗

Malignant uveal melanoma and simulating lesions: MR imaging evaluation.

Twenty-one patients with intraocular disease were studied by magnetic resonance (MR) imaging and computed tomography (CT). In 13 cases, malignant uveal melanoma was considered the likely diagnosis. Both imaging methods were accurate in determining the location and size of uveal melanomas. MR imaging was superior for the assessment of possible associated retinal detachment, for assessment of vitreous change, and for differentiating uveal melanoma from choroidal hemangioma and choroidal detachment. A case of retinal gliosis could not be differentiated from uveal melanoma by either technique. Uveal melanomas appeared as hyperintense lesions on T1-weighted images and as hypointense lesions on T2-weighted images. High signal intensity of the vitreous was observed in patients with vitritis and in those who were thought to have protein leaking into the vitreous as a result of impairment of the retinal-blood barrier.

Adult↗

Magnetic resonance imaging and computed tomography of choroidal detachment.

The magnetic resonance imaging (MRI) and computed tomography (CT) findings in 9 patients with hemorrhagic choroidal detachment, serous choroidal detachment and/or ocular hypotony, choroidal effusion and 6 patients with exudative retinal detachment are described. Subacute hemorrhagic choroidal detachment appeared as moderately hyperintense image in T1 weighted MR scans and as hypointense in T2 weighted scans. Chronic hemorrhagic choroidal detachment was seen as hyperintense image in T1 and T2 weighted scans. Serous choroidal detachment and choroidal effusion appeared as moderately hyperintense image in T1 and T2 weighted scans. The exudative retinal detachment characteristically appeared on MR scans as a dependent hyperintense object in T1 and T2 weighted scans.

Choroid Diseases↗

Radiologic diagnosis of nonsquamous tumors of the head and neck.

Nonsquamous cell tumors of the head and neck can be reliably identified and often accurately diagnosed by proper state of the art radiologic assessment. For optimal diagnostic and preoperative work-up of head and neck lesions, complete radiologic analysis is now essential.

Head and Neck Neoplasms↗