[Radiologic methods and prognosis of nucleolysis in the treatment of sciatica due to a herniated disk].
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Biomedical subjects
Publications and source records attributed to M F Bellin.
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Double-contrast enema (DCE) remains the primary diagnostic exploration. Its specific method and interpretation require skillful handling. Unlike colonoscopy, DCE results in false-positives, the frequency of which varies widely in function of the skill of the interpretation. False negatives reach a significant level from a threshold of size which can be fixed at 5 mm. Despite these drawbacks, double-contrast enema, which is an exploration involving a two level of invasiveness and which provides a good panoramic image of the colon should remain the primary exploration in routine check-ups. DCE is an essential part of loco-regional evaluation. It is important in post-operative check-ups to screen for relapses. Post-operative follow-up should be systematic, involving an initial reference examination after 4 months, a check-up every 6 months for two years and then an annual check-up.
Fifty four computed (CT) examinations were performed on patients with bladder carcinoma. A pathological assessment was obtained in 24 cases and the accuracy of CT in local staging was 91%. The accuracy of CT in detecting lymph nodes invasion was also 91%. Moreover, CT is helpful in the follow-up of patients under treatment. As it provides a correct pre-therapeutic evaluation in 83% cases, CT appears as an effective examination to perform in the evaluation of bladder carcinoma.
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Twenty-two patients with recurrent nerve paralysis without a cervical cause were studied by CT of the mediastinum. Positive findings were present in 22 cases, including one false-positive case. The CT findings were not apparent on chest X-ray film in five of nine cases with mediastinal lymph node involvement, five of nine mediastinal tumors, and two of three cases of vascular etiology. We suggest that CT of the mediastinum is a good examination to search for the etiology of recurrent nerve paralysis without a known cervical cause.
Local, regional lymph node involvement is an essential prognostic factor and an important determinant of treatment choices for patients with retroperitoneal and pelvic cancer. Current cross-sectional imaging modalities, including computed tomography and magnetic resonance (MR) imaging, use the nonspecific criterion of size and are limited in their ability to differentiate benign from malignant lymph nodes. MR lymphography is a promising imaging modality in differentiating benign from metastatic lymph nodes and provides information on lymph node morphology and function. Ultrasmall superparamagnetic iron oxide (USPIO) particles with a long plasma circulation time are suitable as an MR contrast agent for intravenous MR lymphography. They are taken up by macrophages in normally functioning nodes and reduce the signal intensity of tissue in which they accumulate because of T2 and susceptibility effects of iron oxide. In metastatic nodes, macrophages are replaced by cancer cells, which lack reticuloendothelial activity and cannot take up USPIO. The main mechanisms that might explain a heterogeneous node appearance after USPIO injection are discussed. In published reports, USPIO has shown high degrees of sensitivity and specificity for characterizing lymph nodes in cancer patients. We review the development of USPIO compounds, their imaging characteristics, and our clinical experience.
The kidney is the most commonly injured genitourinary organ. The diagnosis and treatment depend on the mechanism of injury (blunt or penetrating trauma), the clinical presentation, and the extent of the lesions. Knowledge of the different appearances of the posttraumatic kidney on imaging studies is essential for prompt and effective treatment of patients. This pictorial essay reviews the imaging evaluation and principal imaging findings associated with blunt and penetrating renal trauma. The role of computed tomography is emphasized because it is a very sensitive, specific, and accurate modality in detecting the presence or absence of injury and defining its extent.
This report describes the CT and MRI features of rectal malacoplakia in a renal transplant recipient. The lesion appeared strongly hyperdense (105 HU) on unenhanced CT and demonstrated hypointense signal on T1- and T2-weighted MR imaging with slight homogeneous enhancement after gadolinium injection. These characteristics distinguish this lesion from other more common neoplastic, inflammatory rectal lesions that are typically isointense on T1-weighted imaging and enhance variably after gadolinium injection. Characteristic intracytoplasmic siderocalcific spherules in malacoplakia can produce suggestive features on unenhanced CT and MRI.
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The low osmolality iodinated contrast agents (ICA), ionic or non ionic are now suggested too replace the usual high osmolality ICA. The main arguments are the better clinical tolerance and a lower renal toxicity. Recent experimental studies have clearly demonstrated that the low osmolality ICA presents a lower renal toxicity. On the rat, we have confirmed that the in vivo renal toxicity of low osmolality ICA, is lower than the high osmolality ICA toxicity. It is clearly demonstrated on man than the enzyme urinary excretion and proteinuria are little or not modified by the low osmolality ICA, but both are increased by high osmolality ICA. These changes are found with a normal glomerular filtration flow. No difference are noted in the creatinine concentration and clearance follow-up. However it is possible that the necessary population of patient to get statistically significative differences between both agents can be superior to the number of patients studied. In clinical practice, we think, that low osmolality ICA must be used for patients presenting one or several risk factors of acute renal failure.
The authors provide a didactic analysis of the errors in perception that can lead to false-negative findings in the detection of advanced rectocolonic cancers with double-contrast enema. They consider 5 categories of images as typical, ie. transverse or horizontal linear opacities, abnormal lumen due to haustral folds on semiaxial views, "pool sign", amputation of the cecum and irregular hypertrophy of the ileocolic valve. These mistakes will become exceptional if the double-contrast images are studied thoroughly using precise rules, and the percentage of false-negative findings in the detection of rectocolonic cancers should thus be reduced to 1%.
Nineteen cases of focal infectious lesions of renal parenchyma studied included 10 cases of acute focal bacterial nephritis (AFBN) and 9 of abscess, cases of pyelonephritis without radiological signs being excluded from this report. Each patient had been investigated by intravenous urography (IVU), ultrasound and CT scan imaging. Comparison of value of the different radiological explorations showed that urographic signs were inconstant and only weakly specific, the most valuable examination being CT scan imaging. The latter images show hypodense zones, clearer with contrast, of a rather triangular form and either single or multiple in AFBN, and mainly nodular images in abscess cases. Ultrasound is of intermediate value, being of high performance in cases of abscess but failing to demonstrate AFBN in about half the cases. However, it should not be totally neglected because of its case of access.
When confronted with rectorrhagia in a young patient, combining a straight abdominal examination with a barium enema investigation may reveal the presence of phleboliths, atypical by their large number and central localization, and orientate towards the rare diagnosis of a colorectal hemangioma.
The use of the prone position in aortography improves the visualization of the anterior wall of the aorta. This is supported by observation of an obstructed aortobifemoral by-pass and seems interesting in the study of aneurysms. More often, it is useful in case of decreased blood flow or increased local turbulence.