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Biomedical subjects

M Endo

Publications and source records attributed to M Endo.

At least 937 records · Page 52Linked to original sources
PubMed1984

Software correction of scatter coincidence in positron CT.

This paper describes a software correction of scatter coincidence in positron CT which is based on an estimation of scatter projections from true projections by an integral transform. Kernels for the integral transform are projected distributions of scatter coincidences for a line source at different positions in a water phantom and are calculated by Klein-Nishina's formula. True projections of any composite object can be determined from measured projections by iterative applications of the integral transform. The correction method was tested in computer simulations and phantom experiments with Positologica. The results showed that effects of scatter coincidence are not negligible in the quantitation of images, but the correction reduces them significantly.

Models, Structural↗
PubMed1984

Improved analytical method for the hexuronic acids at the reducing terminals of glycosaminoglycans.

When endo-uronidases act on glycosaminoglycans, the reaction products have hexuronic acid residues at the reducing terminals. An analytical method for hexuronic acids at the reducing terminals was devised for hyaluronate oligosaccharides having hexuronic acid residues at the reducing terminals. The procedure is as follows: Hexuronic acid residues at the reducing terminals of hyaluronate oligosaccharides were tritiated with reduction using NaB[3H]4 and the products were hydrolyzed with trifluoroacetic acid and nitrous acid. As a result, the tritiated and reduced hexuronic acid residues, that is aldonic acids, were liberated from the reducing terminals. After passing them through anion and cation ion-exchange resins, the aldonic acids were lactonized. The lactones were developed on paper chromatography, and their radioactivities determined on the paper. The method is also useful for discrimination between glucuronic acid and iduronic acid at the reducing terminals of glycosaminoglycans.

Chromatography, Paper↗
PubMed1984

The application of the Milner-Avigad method for the quantitative determination of endouronidase activities.

The Milner-Avigad method (Milner, Y. and Avigad, G. (1967) Carbohydr. Res. 4, 359-361) has been shown to have high specificity for measuring the reducing powers of free hexuronic acids; its applicability in the quantitative determination of endouronidase activity was the purpose of this investigation. Among the constituent monosaccharides of glycosaminoglycans, hexuronic acids showed high color yield by this method, while xylose, galactose and N-acetylhexosamine recorded negligible color yield. Among the monosaccharide residues at the reducing terminals of oligosaccharides, only hexuronic acids exhibited color yield. However, the color yield was less than that of free hexuronic acids. Gel filtration chromatography of reaction products revealed that the cleavage of the oligosaccharide chains and the resultant exposure of new reducing terminals were not caused by the reaction procedures involved in this method. These data indicate that the Milner-Avigad method is useful for determining the presence of hexuronic acid residues preferentially at reducing terminals of glycosaminoglycan moieties. Thus, it supported the conclusion that the Milner-Avigad method is applicable for the quantitative determination of endouronidase activity using glycosaminoglycan as a substrate.

Animals↗
PubMed1984

Second report of an experimental study of cerebrocardiopulmonary resuscitation (CCPR) in dogs with reference to a new continuous brain cooling method, using a Resusci Pump TM-1.

In our previous report, the effect of CCPR (an intracarotid hypothermic infusion combined with the existing CPR) has been described by the authors on dogs in which cardiac arrest had been induced by the inhalation of nitrous oxide. This report contains a new continuous brain cooling method, using a Resusci Pump TM-1 which has been newly devised by us and which has a carotid-carotid bypass in order to reduce oxygen consumption and cerebral metabolism while maintaining a continuous cerebral blood flow. Cardiac arrest was induced experimentally by electrical stimulation. The duration of cardiac arrest was 5 to 10 min duration. The continuous brain cooling was carried out during the period of 10-30 min. Through the experiment, we have investigated vital signs, acid base balance, cardiac output, carotid arterial blood flow, oxygen availability of the brain tissue, and regional cerebral blood flow in both groups of CPR and CCPR . As for the clinical signs and cardiac output, there were no significant differences between two groups. Oxygen availability of the brain tissue and regional blood flow were much more improved in CCPR group than in CPR group. The brain was selectively cooled by means of the continuous brain cooling. This resulted in the minimum effect on circulatory and respiratory system as compared to the effects caused by general hypothermia. Furthermore, the continuous brain cooling decreased cerebral metabolism and CMRO2, and prevented a progressive development of cerebral hypoxia Cerebral perfusion at a given constant pressure may protect the brain tissue from the disturbance of cerebral microcirculation. Therefore, we might expect the continuous brain cooling to have a beneficial effect on cerebral respiration, circulation and metabolism.

Acid-Base Equilibrium↗
PubMed1984

Conduction disturbance in Behçet's disease. Association with ruptured aneurysm of the sinus of valsalva into the left ventricular cavity.

Cardio-Behcet's disease is not often reported; only one case to our knowledge has described complete atrioventricular (AV) block, without pathologic details. We document, from direct observation during surgery and pathologic examination of associated lesions, a case whose conduction disturbance was possibly caused by direct extension of Behcet's disease itself into the conduction system.

Aortic Rupture↗
PubMed1984

A case of insulin resistance associated with acanthosis nigricans.

We described here a 12-year-old male patient with the syndrome of insulin resistance and acanthosis nigricans type A. Insulin levels at fasting state and after glucose loading were 149 +/- 63 microU/ml (mean +/- S.D.) and over 1,000 microU/ml respectively, while the fasting level of blood glucose was 77.7 +/- 8.9 mg/ml (mean +/- S.D.). A marked resistance to exogenous insulin was observed. Circulating levels of insulin antagonists such as growth hormone, cortisol and glucagon were within the normal range. Proinsulin was less than 5% of the radioimmunoassayable insulin. No insulin antibody or antireceptor antibody was detected. Insulin binding to mononuclear cells was decreased to about 50% of the controls. Analysis of membrane receptors demonstrated the normal average affinity, dissociation kinetics and negative cooperativity with a decreased number of receptors. After two days fasting, plasma IRI levels decreased to 27 microU/ml, while insulin binding kinetics were not affected; which suggests that the receptor decrease was not secondary to hyperinsulinemia. These findings indicate that the decreased number of receptors was one of the causes for insulin resistance in this patient.

Acanthosis Nigricans↗
PubMed1984

[Percutaneous transluminal coronary angioplasty and intra-operative angioplasty].

Percutaneous transluminal coronary angioplasty (PTCA) was reviewed with respect to its history, principles, indications and complications. We also reported our experiences with this technique. PTCA was useful in selected cases, but we encountered eight complications among 90 procedures; namely, coronary spasm, coronary dissection and recurrent stenosis. Since 1980 we have used this transluminal angioplasty for 16 patients during aorto-coronary bypass grafting surgery. We also discussed preliminary results in the use of this newly developed technique.

Adult↗
PubMed1984

Anorexia nervosa precipitated by a prepubertal pyometra.

A severe pyometra was found in a typical case of anorexia nervosa, with the latter illness apparently precipitated by the former. Compulsory alimentation before and after operation brought some weight gain as well as reversal of dilated cerebral sulci and hypothyroidism, though hypothalamo-pituitary dysfunction persisted.

Anorexia Nervosa↗