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Biomedical subjects

M Endo

Publications and source records attributed to M Endo.

At least 865 records · Page 48Linked to original sources
PubMed1986

Minute lesions of esophageal cancer.

Fifty-four cases of minute esophageal cancer (1 cm or less in the greatest dimension) were collected and analyzed. Of these 67% were mucosal cancer and 28% were submucosal cancer. Prognosis was anticipated to be good as there was only one case of lymph node metastasis and three of vascular invasion. A lesion of 1 cm can be regarded as curable regardless of its depth of invasion. The endoscopic approach with use of a dye staining technique is useful for detection of or screening for minute esophageal cancer.

Adult↗
PubMed1986

Fast dynamic study in cardiac positron CT using 13N-ammonia in man.

Fast dynamic studies with positron computed tomography (PCT) of the heart have been relatively few because of the technical limitations of prevalently used PCT devices. In the present study, we used a high-sensitivity, whole-body multislice PCT device (POSITOLOGICA-II) and performed serial 6-s PCT scans after the intravenous bolus injection of 13N-ammonia in 15 cardiac patients and 5 normal subjects. On the first image (0-6 s), 13N activity was primarily in the right atrium and ventricle. On the third image (12-18 s), it was primarily in the left atrium and ventricle. These blood-pool images permit evaluation of size and configuration of ventricles and atria in cardiac patients and normal subjects. Clearance of 13N activity in the blood pools and lungs occurred primarily during the 1st min. Thereafter, the myocardial images were delineated. In patients with heart failure, delayed clearance of the tracer from the blood pools and lungs was observed. The results indicate that initial passage of the tracer through the heart can be observed with the use of fast dynamic PCT.

Adult↗
PubMed1986

A method for the identification of sulfated glycopeptide by two-dimensional electrophoresis on cellulose acetate membrane.

Two-dimensional electrophoresis on cellulose acetate membrane permits the clean separation of sulfated glycopeptide in a mixture of acidic glycans (glycosaminoglycans and acidic glycopeptides). Two systems were used. In system 1, 0.1 M pyridine-0.47 M formic acid buffer (pH 3.0) was used in the first and 0.1 M barium acetate (pH 8.0) in the second dimension. In system 2, 0.1 M pyridine-0.47 M formic acid buffer (pH 3.0) was used in the first and 0.1 M HCl in the second dimension. All of the acidic glycans on electrophoretogram were stained with alcian blue in 70% ethanol. On the other hand, sulfated glycans alone were made visible with alcian blue in 0.1 M HCl. Alcian blue in 70% ethanol or 0.1 M HCl, when combined with periodic acid-Schiff's reagent identified sulfated glycopeptides on cellulose acetate membrane.

Electrophoresis↗
PubMed1986

Early detection of adenocarcinoma of the esophagus.

Fifty-two cases of primary adenocarcinoma of the esophagus were studied with respect to their origin and features in the early stage. The origin of the tumor was determined in 12 cases. Six cases arose in Barrett's esophagus, 5 cases in esophageal glands, and one case in ectopic gastric mucosa. The postoperative prognosis was closely related to the invasion to the adventitia. Tumors with no adventitial invasion showed excellent results, and their early detection is recommended. Submucosal tumors arising in Barrett's epithelium or in leading ducts of esophageal glands presented as small elevated lesions at endoscopy. On the other hand, tumors arising in submucosal glands showed diffuse infiltration into the esophageal wall and were difficult to detect in the early stage. Endoscopic examination aided by the staining method or brush cytology is recommended.

Adenocarcinoma↗
PubMed1986

Interstitial deletion of the long arm of chromosome 8 without Langer-Giedion syndrome.

A case of interstitial deletion of the long arm of chromosome 8 is reported. A chromosome analysis by a high resolution banding revealed the abnormal karyotype, 46, XY, del (8) (q11.2q13). Although some reports describe an association of 8q deletion with the Langer-Giedion syndrome, this patient did not have the typical features of this syndrome. It was noted that the patient had amino aciduria, EEG and ECG abnormalities together with other pathological findings.

Adolescent↗
PubMed1986

[Aneurysm of a diverticulum of the ductus arteriosus in an adult: a case report].

An aenurysm of a diverticulum of the ductus arteriosus in a 33-year-old man was presented. The chest radiography revealed a mass obscurring the aortic window above the hilus of the left lung. His blood pressure was 130/70 mmHg, and there was no difference in pressures between the upper and lower or between the right and left extremities. A CT scan of the chest showed 30 X 34 mm angioma adjacent to the descending aorta and pulmonary artery. Aortography and contrast radiography of the right ventricle revealed a cystic pedunculated aneurysm at the superior portion of the descending aorta. The base of the left pulmonary artery was slightly displaced. There was no communication between the aorta and pulmonary artery, nor was any significant difference in pressure between the ascending and descending aorta. This case was diagnosed as an aneurysm of the diverticulum of the ductus arteriosus, and then it was resected. The abnormality was confirmed by the localization of the aneurysm and histopathologic findings, but the presence of the ligamentum arteriosum was not confirmed. This is the 23rd case of the aneurysm of the diverticulum of the ductus arteriosus in adults, and the first case in Japan in which the diagnosis was made in a living patient, followed by successful surgery.

Adult↗
PubMed1986

Studies on hepatobiliary lymph flow with radioactive colloid--for lymph node metastasis resection of carcinoma of the bifurcation of hepatic duct.

Hepatobiliary lymphoscintigraphy by Technetium 99m-rhenium colloid (99mTc-Re colloid) using a fine needle guided by ultrasonography was performed on 12 patients who underwent resection of the hepatoduodenal ligament lymph nodes. Histological examination revealed no lymph node metastasis in 8 patients. In 4 patients in whom 99mTc-Re colloid was injected into the left medial inferior hepatic segment, periarterial lymph nodes showed higher isotope uptake count than periductal nodes, and lymph nodes around the common hepatic artery revealed higher values than superior posterior pancreatoduodenal nodes. On the contrary, in 3 patients in whom the isotope was injected into the right anterior inferior segment, periductal lymph nodes had higher values than periarterial nodes, and superior posterior pancreatoduodenal lymph nodes showed higher values than those around the common hepatic artery. In one patient in whom the isotope was injected into both right and left segments, superior posterior pancreatoduodenal lymph nodes showed similar values to those around the common hepatic artery. Periportal lymph nodes tended to have values between those of periarterial and periductal ones. Lymph node metastases were confirmed in 4 patients in whom the relationships mentioned above was not always observed, and periportal lymph nodes showed the highest values among the three.

Adenocarcinoma↗