Search PubMed⌕ Search

Biomedical subjects

M Eldar

Publications and source records attributed to M Eldar.

135 records · Page 8Linked to original sources

Depressed PHA transformation and acute leukemia in macroglobulinemia.

Two out of fifty-three patients with macroglobulinemia developed acute leukemia following chemotherapy. The Phytohemagglutinin (PHA) Transformation Index performed prior to the appearance of acute leukemia was found to be markedly depressed in these two patients in comparison with ten other patients with macroglobulinemia. In addition, a clone with monosomy 7 was detected in one of the currently reported patients when the leukemic process became apparent. The cytogenetic analysis was normal in the same patient 48 months earlier, when macroglobulinemia was diagnosed. The low PHA Transformation Index and the chromosomal hypodiploidy are of interest and their clinical significance merits further investigation.

Adolescent↗

Pulmonary alveolar proteinosis associated with fanconi's anemia.

A 16-year old patient with Fanconi's anemia developed pre-leukemia and pulmonary infiltration which was found upon autopsy to be pulmonary alveolar proteinosis. The question whether the pulmonary alveolar proteinosis was due to the marked leukopenia and an eventual defective phagocytic ability of the leukocytes is raised.

Adolescent↗

Squamous cell carcinoma associated with sarcoidosis in the lung.

A male patient, operated for squamous cell carcinoma of the lung, in whom sarcoidosis was discovered in the resected lung specimen, is reported. The increased association of sarcoidosis along with malignant diseases is discussed, as well as the various mechanisms probably responsible for this association.

Aged↗

Changes in blood pressure in the lying and sitting positions in normotensive, borderline and hypertensive subjects.

Blood pressure of hypertensive subjects reacts differently from that of borderline or normal subjects at rest in either sitting or lying positions. In the hypertensive group the diastolic pressure tends to rise more on consecutive measurements and the systolic blood pressure tends to fall less than in the two other groups. Similarly, on going from the lying to the sitting position, diastolic blood pressure of hypertensives rises less than that of normotensive or borderline hypertensive individuals. Thus, people with 'casual' hypertension differ in their reaction to rest and changes in body position in their reaction to rest and changes in body position with respect to normotensives or borderline hypertensives. This behavior could lead to labelling of subjects as 'normal' or 'hypertensive' depending on position and timing of the blood pressure measurement.

Blood Pressure↗