Normal values at 37 degrees for serum lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase and glycerate dehydrogenase.
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Adolescent↗
Biomedical subjects
M E Watson
Publications and source records attributed to M E Watson.
Transient systolic hypertension after aortic valve replacement.
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Aortic Valve↗
iMPACT3: Internet-based development and administration of utility elicitation protocols.
iMPACT3 (Internet Multimedia Preference Assessment Instrument Construction Tool, version 3) is a software development environment that helps researchers build Internet-capable multimedia utility elicitation software programs. The program is a free, openly accessible Web site (http.// preferences.ucsd.edu/impact3/asp). To develop a utility elicitation software program using iMPACT3, a researcher selects modular protocol components from a library and custom tailors the components to the details of his or her research protocol. iMPACT3 builds a Web site implementing the protocol and downloads it to the researcher's computer. In a study of 75 HIV-infected patients, an iMPACT3-generated protocol showed substantial evidence of construct validity and good internal consistency (logic error rates of 4% to 10% and procedural invariance error rates of 10% to 28%, depending on the elicitation method) but only fair 3- to 6-week test-retest reliability (intraclass correlation coefficient= 0.42 to 0.55). Further work may be needed on specific utility assessment procedures, but this study's results confirm iMPACT3's feasibility in facilitating the collection of health state utility data.
Adult↗
The first assistant's role in managing phacoemulsification complications.
Every surgeon who performs phacoemulsification will encounter complications. Successful management of complications is enhanced by a combination of surgical skill, good judgment, and a well-trained, highly motivated first assistant. The first assistant must have already mastered the names and uses of all instruments and equipment, and will have practiced the eye/hand coordination necessary to work comfortably with microscopes and loupes. A positive attitude and total concentration on the procedure and the surgeon is imperative. A complete understanding of the management of the most common complications will enable the assistant to begin setting the stage to manage a complication during the anticipatory phase.
Cataract Extraction↗
Role of the first assistant in ophthalmic surgery.
1. As the number of Ambulatory Surgery Centers increases and the Medicare reimbursements for surgeon first assistants decline, the need for non-physician first assistants grows. 2. Qualifications for a first assistant include knowledge skill, and devotion to this speciality. 3. The first assistant is part of a medical team that consists of the surgeon, the first assistant, the scrub nurse or technician, and the circulating nurse. 4. The role of the first assistant helps to increase efficiency in the operating room and enhance the quality of patient care.
Hospitals, Special↗
The effect of macrophage conditioned media on Leydig cell function.
Primary gonadal failure frequently occurs in male patients with serious illness. This has suggested that activation of the immune system may affect the endocrine function of the testis. Most previous studies have evaluated the effects of individual cytokines on testosterone (T) production but with conflicting results. The present study was performed to compare the effects on Leydig cell function of a mixture of cytokines found in macrophage conditioned media (MCM), with that of individual recombinant cytokines. The MCM was found to contain an acid stable, heat labile, 16.5 kD factor(s) which significantly decreased the production of testosterone (T), dihydrotestosterone (dHT), adenosine 3':5'-cyclic monophosphate (cAMP), and guanosine 3':5'-cyclic monophosphate (cGMP). The MCM had no effect on the specific binding of human chorionic gonadotropin (hCG) but decreased the activity of 3-beta-hydroxysteroid dehydrogenase (3-beta-HSD) (a regulated Leydig cell enzyme). Neither tumor necrosis factor alpha (TNF alpha) interleukin 1 alpha (IL1 alpha), interleukin 1 beta (IL1 beta), interleukin 2 (IL2), interleukin 6 (IL6), or human interferon alpha,beta (IFN alpha,beta) had a similar effect. These results show that the cytokines or other factor(s) contained in MCM are potent regulators of T production, which could be important in understanding the low serum T levels associated with serious illness.
3-Hydroxysteroid Dehydrogenases↗