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Biomedical subjects

M E Stewart

Publications and source records attributed to M E Stewart.

77 records · Page 5Linked to original sources

Adolescents in a therapeutic community: treatment implications for teen survivors of traumatic experiences.

This article describes an adolescent with a history of severe traumatic experiences and treatment in a residential program for chemically dependent, severely emotionally disturbed youths between the ages of 12 and 18. It begins with a description of the long-term treatment program, the types of clients admitted, and the treatment activities provided. Basic findings from an outcome study conducted within the program made predictions regarding the length of time of residential treatment for drug addicted, severely emotionally disturbed adolescents regardless of trauma history. Pretreatment psychiatric functioning was addressed by utilizing GAF scores from the DSM-III-R for each of the participants in the study. Of 102 participants in the study, 34 were survivors of sexual abuse, physical abuse, or devastating natural disasters. A clinical case of a traumatized adolescent is presented in relation to adolescent identity, the distinction between adolescent and adult treatment, and a variety of treatment strategies that can influence an abused adolescent's long-term recovery from both addiction and trauma, including retention in treatment, the developmental stage of adolescence, identification and diagnosis of trauma during adolescence, building a working alliance, individual psychotherapy, psychopharmacology as an aid to psychotherapy, psychological debriefing, and group psychotherapy.

Adolescent↗

Cisplatinum and prednimustine, an active regimen for advanced epithelial ovarian cancer.

80 patients with advanced epithelial ovarian carcinoma were treated for 6 months with cisplatinum and prednimustine following initial surgery. Response to treatment was assessed by second-look surgery. The objective response rate was 69% with 38% achieving a complete response for up to 55 months. The toxicity of this regimen was acceptable. Statistically, de-bulking or partial de-bulking had a significant beneficial effect on the likelihood of a complete response. The best survival figures were associated with maximum de-bulking. The combination of cisplatinum and prednimustine is a new and active regimen for operable advanced epithelial ovarian carcinoma.

Adult↗

Radiology of the diaphragm as two muscles.

In order to investigate the postulate that the diaphragm consists of two muscles, cineradiographic studies and plain roentgenograms were taken of the diaphragmatic movement in eight dogs. A characteristic pattern of contraction was seen following direct electric stimulation of each of the sections of the diaphragm, namely the costal muscle, mainly anterior to the central tendon, and the smaller, posterior crural muscle. Stimulation of the roots of the phrenic nerves in the neck showed that, with C5 root stimulation, contraction of the costal area occurred, but that with C6 and C7 root stimulation, contraction of the crural area occurred, although the movement was larger with C6 than with C7 root stimulation. Downward displacement of the entire diaphragm followed stimulation of the intrathoracic phrenic nerves. These results support the concept that the canine diaphragm actually consists of two muscles with a different segmental innervation of each part.

Animals↗