Institutionalized retarded subjects (N=57) were assigned to one of three experimental conditions during a simple three-choice task in which the subjects and the experimenter took turns feeding colored plastic "Cookie Monster." In the imitation condition, the experimenter imitated the subject's choice, and in the ninimtation condition, the experimenter avoided imitating the subject. Following imitation or nonimitation, the subject was given opportunities to imitate the experimenter. In the modeling only condition, the subject's choice always followed the experimenter's so that the subject always had the opportunity to imitate. Analysis of variance revealed a significant difference among the three conditions (p less than .008) in the subjects' tendency to imitate the experimenter. Paired comparisons between conditions showed that subjects in the imitation condition imitated significantly more (p less than .05) than subjects in either the nonimitation or modeling only condition. The nonimitation and modeling only conditions did not differ significantly. Theoretical and practical implications of the findings were discussed.

Child↗

PubMed1976

Adrenal aldosterone-producing adenoma: use of colonic potential in diagnosis and subtraction scanning technique for localisation.

Primary hyperaldosteronism is a potentially curable cause of hypertension, and much interest has been shown in methods of diagnosing the associated hypokalaemic hypertension and localising the adrenal adenoma. In two patients the diagnosis of primary aldosteronism was confirmed by colonic potential measurement and the adenoma localised by a new subtraction technique for early adrenal imaging applied to the use of 131I-19-iodocholesterol. Both patients underwent adrenalectomy and in each case an adenoma was removed. Blood pressure and electrolyte levels returned to normal after operation. In one patient bilateral adrenal phlebography had failed to show the tumour, and sampling of aldosterone concentrations in the adrenal veins had been unsatisfactory.

Adenoma↗

PubMed1976

Hematoporphyrin derivative: a possible aid in the diagnosis and therapy of carcinoma of the bladder.

The distribution of hematoporphyrin derivative has been studied in patients undergoing transurethral resections and total cystectomy for carcinoma of the bladder. Although hematoporphyrin derivative fluorescence was not confined to malignant tissues with the dose used there was preferential localization in malignant and pre-malignant epithelium. Also high intensity illumination of an area of hematoporphyrin derivative sensitized carcinoma caused tumor destruction. Therefore, it is suggested that hematoporphyrin derivative could be used as an aid to the diagnosis and treatment of carcinoma of the bladder.

Hematoporphyrins↗

PubMed1975

Photodynamic destruction of human bladder carcinoma.

Eleven human bladder carcinomata of different degrees of differentiation were implanted in mice immunosuppressed by thymectomy, anti-thymocyte serum and x-rays. Seven carcinomata grew well and one poorly and 3 produced mainly fibrous nodules in the mice. Normal human bladder tissues were grown from 4 other patients. The administration of a haematoporphyrin derivative (HpD), followed 24 h later by exposure to white light, caused marked destruction of tumours but little or none of normal bladder tissues. HpD or light alone caused no damage to tumours or normal tissues. It is suggested that photodynamic therapy may be applicable in the treatment of superficial transitional cell carcinoma of the bladder.

Animals↗

PubMed1974

Studies on the preservation of kidneys under hyperbaric oxygen after significant warm ischemia.

Explore the source record for details and available documents.

Animals↗

PubMed1972

Kidney preservation by surface cooling: analysis of 130 transplants.

An analysis of 130 consecutive cadaveric renal transplants has shown the effectiveness of simple surface cooling of organs before transplantation. The primary graft failure rate was 10%, and kidneys could be stored for periods of up to 12 hours including warm ischaemia times of 150 minutes. Forty-eight patients received haemodialysis before transplantation and 78 patients received peritoneal dialysis. There were significant differences in the incidence of tubular necrosis in the two groups: these may have been linked to the differences in fluid and osmotic load presented to the transplants.

Acute Kidney Injury↗

PubMed1972