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Biomedical subjects

M E Nichitaĭlo

Publications and source records attributed to M E Nichitaĭlo.

At least 19 recordsLinked to original sources
PubMed2006

[Laparoscopic interventions for adrenal gland tumor].

Clinical course, hormonal characteristics and efficacy of rehabilitation were studied by the authors in 12 patients with suprarenal gland tumor, operated, using minimally invasive endoscopic intervention--laparoscopic adrenalectomy (LA). Efficacy, indications, contraindications, role of LA in the treatment of surgical adrenal diseases were analyzed. LA is characterized by invasiveness and traumaticity, adequate radicalism, quick rehabilitation, and good remote results. LA is indicated for the treatment of majority of hyperplastic and tumoral diseases of suprarenal glands: it is possible to operate 60% of patients with surgical diseases of suprarenal glands using endoscopic technology.

Adrenal Gland Neoplasms↗
PubMed2006

[Modern tendencies in diagnosis and treatment of an acute destructive pancreatitis].

The problem of an acute pancreatitis was one of "key" ones in investigations of A. A. Shalimov and his school. While the knowledge concerning the disease pathogenesis improved, diagnostic and treatment algorhythm elaborated, modern medicinal preparations and surgical treatment introducted, including miniinvasive technologies, so also approaches to treatment of patients, suffering an acute pancreatitis, have changed.

Humans↗
PubMed2006

[Modern tactics for choledocholithiasis treatment].

There is presented tactics of treatment of 1325 patients, in whom choledocholithiasis was diagnosed. In 1023 (7.4%) of them in the first stage endoscopic papillosphincterotomy was performed and transpapillar endobiliary manipulations, in 1-2 days--laparoscopic cholecystectomy. In 302 (2.9%) patients laparoscopic exploration of common biliary duct with cholecystectomy were performed. Intraoperative complications occurred in 28 (2.7%) and postoperative--in 72 (7%) patients. All patients are alive.

Cholecystectomy, Laparoscopic↗
PubMed2006

[Complications of endoscopic transpapillary interventions].

The results of endoscopic papillosphincterotomy with subsequent endobiliary intervention performance in the clinic in 2235 patients in 2000-2006 yrs were studied up. Early complications had occurred in 113 (5.1%) patients, including hemorrhage--in 57 (50%); late complications--in 64 (2.9%). All the patients are alive.

Adult↗
PubMed2006

[Surgical correction of the biliary ducts injury while performance of laparoscopic cholecystectomy].

There were analyzed the results of treatment of 65 patients, in whom unintended injury of biliary ducts occurred while performance of laparoscopic cholecystectomy in 1993-2005 yrs, including 9 patients, operated in the clinic and 56--in other hospitals. For correction of intraoperatively revealed injuries of biliary ducts there were formated bilio-biliary anastomosis, cholecystoenteroanastomosis--in 1, hepaticojejunoanastomosis end to side (in 2), "high" hepaticojejunoanastomosis (in 5). If the injuries were revealed more lately, application of two-staged treatment was needed in majority of cases. Miniinvasive intervention, as the definitive method of correction, was applied in 11 patients with small injury of biliary ducts, insufficiency of the gallbladder stump sutures due to residual choledocholithiasis, and also as an additive manipulation in the treatment of complete injury of biliary ducts--in 23. Postoperative mortality was 1.5%, and in late period--1.5%.

Adult↗
PubMed2005

[Prophylaxis and treatment of intraabdominal purulent complications after performance of laparoscopic cholecystectomy using interventions with ultrasonographic control].

The results of treatment of 9103 patients, to whom laparoscopic cholecystectomy was performed, were adduced. In 6714 patients intraabdominal postoperative complications were absent, ultrasonographic investigation (USI) was not performed. Dynamical USI was done in 2389 patients, permitting to estimate timely the wound course severity in the gallbladder bed, to administer an adequate therapv, in 9 of them--to perform puncture of subhepatic formations under USI control. Intraabdominal infectious complications were revealed in 65 (0.71%) of patients.

Abdominal Cavity↗
PubMed2005

[Possibilities of miniinvasive interventions in isolated stenosis of lobar biliary ducts].

In 2000-2004 yrs miniinvasive interventions for isolated stenosis of lobar biliary ducts were performed in 27 patients. The stenosis was caused by nontumoral (choledocholithiasis, primary sclerosing cholangitis) or malignant lesion of biliary ducts. Miniinvasive technologies included interventions, using laparoscopic and endoscopic transpapillary accesses. The authors consider expedient and justified the performance of such interventions in present contingent of patients, because this promotes improvements of immediate and late results of treatment and quality of life as well.

Adult↗
PubMed2004

[Dynamics in the local and systemic immune factors in patients with cystic transformation of the bile duct].

Cystic transformation of biliary ducts (CTBD) is a rare inborn anomaly of the biliary system development. For the patients with CTBD quite high metabolic activity of neutrophils according to data of spontaneous test with nitroblue tetrazolium (NBT-test), reduction of IgA content in the initial period, significant raising of interleukin-6 (IL-6) level on the first postoperative day are characteristic. Quantity of active neutrophils of type II in the blood of patients with CTBD depends on antigenic load. Neutrophils in the bile restore the NBT according to type I. Local concentration of IL-6 and IL-8, and also the functional activity of neutrophils in ductal bile in patients with CTBD are the sensitive indexes of clinical state and immunological reactivity.

Adolescent↗
PubMed2004

[Simultaneous operations during laparoscopic cholecystectomy].

Simultant laparoscopic operations were performed in 1993-2003 yrs period in 321 patients, including 287--using laparoscopic and 34--the combined (laparoscopic and open) access. Concurrent diseases were diagnosed preoperatively in 219 (68.2%) of patients and were disclosed while doing intraoperative revision--in 102 (31.8%). The simultant operations performance, as a rule, enhanced mildly the total duration of a basic stage, did not influence the duration of postoperative period and the patients rehabilitation essentially, as well as for frequency of the intra--and postoperative complications occurrence. The authors consider that it is expedient to perform laparoscopic intervention simultaneously for concurrent surgical diseases of abdominal cavity.

Adolescent↗
PubMed2004

[Experimental substantiation of the method of biological tissue welding in surgical hepatology].

Application of the welding method for biological tissues in hepatobiliary surgery was experimentally substantiated. In 14 pigs (25-30 kg body mass) resection of one hepatic lobe, using electric welding method, was done. In control group (4 pigs) the similar operative intervention was accomplished, using conventional method. Application of the electric welding method guarantees secure hemostasis and cholestasis, do not causes specific pathological changes in the adjacent region of affection tissues, speed of restoration of the structures damaged exceeds such in application of the suturing method.

Animals↗
PubMed2003

[Thromboembolic complications in laparoscopic surgery and their prophylaxis].

Frequency of thromboembolic complications occurrence after laparoscopic intervention was studied in 8230 patients. Efficacy of prophylactic perioperative application of low-molecular heparin fraxiparin was estimated. Thrombosis of deep veins had occurred in 6 (0.073%), thromboembolism of pulmonary artery--in 3 (0.037%) patients. General frequency of thromboembolic complications had constituted 0.11%.

Adolescent↗
PubMed2003

[Diagnostic laparoscopy and treatment choice in patients with closed abdominal injuries].

The results of laparoscopic investigations, conducted in 94 injured persons with preliminary diagnosis of closed abdominal trauma were analyzed. Of them in 47 the damage of internal organs was excluded. In an emergent order there were operated on 47 patients. Splenectomy was performed in 28 patients (including 2--in whom simultaneously the hepatic and pancreatic lacerations were closed by sutures), cholecystectomy--in 3, cholecystostomy, drainage of bursa omentalis--in 1, resection of small intestine--in 2, resection of omentum--in 1, closure of the small intestine wounds with sutures--in 3, of the bladder with epicystostomy performance--in 2, of the small intestine mesentery--in 2, of the liver--in 1, drainage of bursa omentalis--in 1, opening of infrahepatic abscess--in 1, examination of retroperitoneal hematoma with drainage--in 2.

Abdominal Injuries↗
PubMed2002

[Experimental application of electrocautery in biliary surgery].

The testing of a new nonsuture electrothermic method of biliary system tissues connection was conducted in laboratory animals--rabbits and pigs. Reactions of tissues and cells in zone of electric influence and the gallbladder suture, remote reactive changes in the operation zone were studied up. In application of the proposed method of the regeneration processes inhibition and specific pathological changes in surrounding tissues were not noted, speed of the damage structure restoration was comparable with such in the tissues connection using suture materials.

Animals↗