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Biomedical subjects

M E Morgan

Publications and source records attributed to M E Morgan.

71 records · Page 4Linked to original sources
PubMed1980

Plasma zinc in psoriatic in-patients treated with local zinc applications.

Zinc is a major component of many local skin applications. An investigation into its systemic absorption in thirty-one psoriatic hospital in-patients is reported. Plasma zinc, copper and whole blood delta-aminolaevulinic acid dehydratase were followed before and during in-patient treatment over 14 days. No significant alteration in these parameters was detected. Significantly reduced plasma zinc levels were found in the patients compared to a matched control population.

Administration, Topical↗
PubMed1973

Volatile compounds produced in sterile fish muscle (Sebastes melanops) by Pseudomonas perolens.

Volatile compounds produced by Pseudomonas perolens ATCC 10757 in sterile fish muscle (Sebastes melanops) were identified by combined gas-liquid chromatography and mass spectrometry. Compounds positively identified included methyl mercaptan, dimethyl disulfide, dimethyl trisulfide, 3-methyl-1-butanol, butanone, and 2-methoxy-3-isopropylpyrazine. Compounds tentatively identified included 1-penten-3-ol and 2-methoxy-3-sec-butylpyrazine. The substituted pyrazine derivative 2-methoxy-3-isopropylpyrazine was primarily responsible for the musty, potato-like odor produced by P. perolens.

Alcohols↗
PubMed1971

Chemical nature of malty flavor and aroma produced by Streptococcus lactis var. maltigenes.

Mature skim milk cultures of Streptococcus lactis var. maltigenes were steam distilled at low temperature under reduced pressure. Ethyl ether extracts were prepared from the distillates and analyzed by gas-liquid chromatography and mass spectrometry. Twenty of 31 components detected in the culture distillates were identified positively and 11 tentatively, whereas 10 of 19 components detected in the heated skim milk control were identified positively and 9 tentatively. Among components detected in the culture distillate, but not detected in the heated skim milk distillate, and which have not been previously identified in milk cultures of the organism were phenylacetaldehyde and phenethanol. Quantitative analyses of the volatiles entrained from milk cultures of several strains of S. lactis var. maltigenes revealed a probable relationship between variation in the character of the aroma of the cultures and the alcohol/aldehyde ratio.

Acids↗
PubMed1967

Decarboxylation of alpha-keto acids by Streptococcus lactis var. maltigenes.

Decarboxylation rates for a series of C-3 to C-6 alpha-keto acids were determined in the presence of resting cells and cell-free extracts of Streptococcus lactis var. maltigenes. The C-5 and C-6 acids branched at the penultimate carbon atom were converted most rapidly to the respective aldehydes in the manner described for alpha-carboxylases. Pyruvate and alpha-ketobutyrate did not behave as alpha-carboxylase substrates, in that O(2) was absorbed when they were reacted with resting cells. The same effect with pyruvate was noted in a nonmalty S. lactis, accounting for CO(2) produced by some "homofermentative" streptococci. Mixed substrate reactions indicated that the same enzyme was responsible for decarboxylation of alpha-ketoisocaproate and alpha-ketoisovalerate, but it appeared unlikely that this enzyme was responsible for the decarboxylation of pyruvate. Ultrasonic disruption of cells of the malty culture resulted in an extract inactive for decarboxylation of pyruvate in the absence of ferricyanide. Dialyzed cell-free extracts were inactive against all keto acids and could not be reactivated.

Butyrates↗
PubMedDate not supplied

Assessment of the PKU card as a retrospective index of neonatal blood lead status.

PKU cards were obtained for 50 one-year-old children whose cord blood lead, maternal blood lead and household water lead were known. These 3 values are known to correlate well. Lead values were measured from the blood on the cards, and correlated significantly with the other values. However, predictive validity was poor due to card contamination and it is felt that, for the individual patient, this is not a reliable retrospective index of blood lead at the time of birth.

Female↗
PubMedDate not supplied

Dosage calculation testing for competency in ambulatory care.

The scope of services provided by the Staff Development Department or clinical educators in healthcare settings includes, but is not limited to, employee orientation, continuing education, and competency assessment. The critical issue of ascertaining competency of nursing staff in medication dosage calculation encompasses each of these functions. The authors describe the process of pilot testing a dosage calculation test in an ambulatory care setting, adapting it based on feedback, using it with orientees and current staff, and using the educational process with nurses needing assistance in dosage calculation.

Ambulatory Care↗