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Biomedical subjects

M E Herrtage

Publications and source records attributed to M E Herrtage.

At least 73 records · Page 4Linked to original sources
PubMed1995

Echocardiographic measurements of cardiac dimensions in normal ponies and horses.

Echocardiographic examinations were performed on 41 clinically normal small ponies, large ponies and horses. Using standardised two-dimensional (2-D) echocardiographic images to guide M-mode studies, the interventricular septal thickness, left ventricular internal dimension and left ventricular wall in systole and diastole, and aortic diameter in diastole were measured. Normal values for these echocardiographic dimensions were obtained across a wide range of bodyweights. Although there was a trend for echocardiographic dimensions to increase with bodyweight across the whole range of animals examined, little or no linear correlation was found between dimensions and bodyweight within the small pony, large pony and horse groups.

Aging↗
PubMed1987

Von Willebrand's disease in dogs in the United Kingdom.

An assay for the measurement of von Willebrand factor antigen has been established. In a period of 18 months, 13 dogs have been identified as suffering from von Willebrand's disease. The affected animals had levels of von Willebrand factor antigen which ranged from undetectable to 43 per cent of normal. Factor VIII levels were also reduced. Haemorrhagic episodes were usually associated with trauma or surgery, and often required transfusion with fresh blood or plasma to arrest haemorrhage.

Animals↗
PubMed1987

Recognition of 'trembler', a hypomyelinating condition in the Bernese mountain dog.

An account is given of a hypomyelinating condition, 'trembler', in the Bernese mountain dog. The condition is manifested clinically as a tremor of the limbs and head which becomes more intense with excitement or stress and which disappears with sleep. The tremor, which is first noticeable between two and eight weeks old, may persist throughout life but decline with age. Examination of plastic embedded tissue obtained post mortem from two, nine-week-old animals showed hypomyelination of the spinal cord. Preliminary examination of breeding data suggests that the condition may be inherited as an autosomal recessive.

Animals↗
PubMed1984

The enzymic defect and storage products in canine fucosidosis.

A marked deficiency of alpha-L-fucosidase and the accumulation of fucose-containing glycoasparagines were found in the brains of two English Springer spaniels suffering from a progressive nervous disorder. Both forms of alpha-L-fucosidase in normal brain, which are separable by ion-exchange chromatography, are absent from the affected animals. The storage products were characterized by t.l.c., gel filtration, g.l.c. and fast-atom-bombardment mass spectrometry. The postulated structures of the main components are: (formula; see text) The enzymic defect and nature of storage products justify designation of this disorder as canine fucosidosis.

Animals↗
PubMedDate not supplied

Primary chondrosarcoma in the pulmonary artery of a dog.

A 5-year-old cross-bred dog was examined with an 8-week history of coughing and a 3-week history of collapsing during exercise. Thoracic radiography revealed moderate right-sided cardiomegaly and a partially mineralized area over the dorsocranial heart base. Echocardiography demonstrated moderate eccentric and concentric right ventricular hypertrophy and a hypoechoic mass in the main pulmonary artery. The owners declined further investigations and the dog died at home 4 days later. Postmortem revealed a primary pulmonary artery chondrosarcoma. This is the first case report of a pulmonary artery chondrosarcoma in a dog and presents another differential diagnosis of syncope in the dog.

Animals↗
PubMedDate not supplied

Magnetic resonance imaging in the diagnosis of lymphoma involving the brachial plexus in a cat.

An 11-year-old, neutered, female Domestic Long Hair cat had a 3-week history of left forelimb lameness. Conscious proprioception and postural reflexes were absent on the left thoracic limb. The cat had slightly reduced placing and hopping responses on the left pelvic limb, absent cutaneous trunci muscle reflex on the left side, and left triceps muscle atrophy. Magnetic resonance imaging revealed a 2 x 2 x 2 cm mass in the region of the left brachial plexus. The cat was treated by left forelimb amputation and hemilaminectomy. Histopathology of the brachial plexus revealed lymphoma.

Animals↗
PubMedDate not supplied

The radiographic appearance of the pulmonary vasculature in the cat.

The purpose of this study was to determine the dimensions of the pulmonary arteries and veins in the cat, both in normal animals and those with evidence of intrathoracic disease. The radiographs of 50 normal cats, 35 cats with hypertrophic cardiomyopathy (HCM), and 15 cats with other intrathoracic disease were assessed. The normal range for the right cranial lobar artery compared with the proximal third of the fourth rib was 0.5-1.0, with a mean artery-to-rib ratio of 0.70 (standard deviation +/- 0.13). Normal cats had a mean vein diameter of (0.20 +/- 0.03 cm) (P = 0.034) compared with cats with HCM, which had a significantly greater mean vein diameter (0.22 +/- 0.04 cm).

Animals↗