Effects of strontium administration on rat molar morphology.
Strontium at concentrations of 0, 50 and 150 mg/l was given to rats during pregnancy and to the pups during a pre- and post-weaning period. Measurements were made on first and second mandibular molars to assess the morphology of tooth and fissure dimensions, and enamel and dentine thickness. A significant increase in horizontal and vertical dentine thickness was associated with a level of 50 mg Sr/l, a concentration previously found to be associated with decreased caries prevalence in rats.