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Biomedical subjects

M E Curzon

Publications and source records attributed to M E Curzon.

At least 91 records · Page 5Linked to original sources

Effects of strontium administration on rat molar morphology.

Strontium at concentrations of 0, 50 and 150 mg/l was given to rats during pregnancy and to the pups during a pre- and post-weaning period. Measurements were made on first and second mandibular molars to assess the morphology of tooth and fissure dimensions, and enamel and dentine thickness. A significant increase in horizontal and vertical dentine thickness was associated with a level of 50 mg Sr/l, a concentration previously found to be associated with decreased caries prevalence in rats.

Animals↗

Relationship of strontium in drinking water and surface enamel.

The Sr content of surface enamel of 233 teeth from nine communities was related to drinking water Sr concentrations. These water concentrations ranged from 0.02 microgram/ml to 33.9 microgram/ml. The relationship between enamel concentrations and water concentrations was linear for water concentrations less than 10 microgram/ml Sr, but leveled off at approximately 300 microgram/gm Sr in the enamel for communities with greater than 10 microgram/ml Sr in drinking water. Binding of Sr to components in the oral environment is proposed as an explanation of this effect.

Adolescent↗

Dental caries and trace element composition of whole human enamel: Western United States.

Samples of whole enamel prepared from 83 teeth were analyzed for the concentrations of 30 trace elements. Samples were from lifelong residents, younger than 20 years of age, of a high-caries area (Oregon) and a low-caries area (California). All samples were caries-free, prepared by standardized methods, and analyzed by spark source mass spectrometry by one laboratory. Elements strongly associated with a high prevalence of caries were copper, and, to a lesser extent, aluminum, sulfur, titanium, chromium, nickel, silver, and tin. A low prevalence of caries was associated with high concentrations of strontium in enamel.

Adolescent↗

Enamel mottling in a high strontium area of the U.S.A.

As part of an epidemiologic study conducted in seven towns in Wisconsin, U.S.A., enamel mottling, opacities, and pigmentations were assessed in 1, 313 12- to 14-year-old schoolchildren. Enamel mottling was found to increase in prevalence and severity as strontium concentrations in communal drinking water increased. This trend held for lifelong residents only, and could not be demonstrated among children who immigrated to the towns after 1 year of life. No relationship of enamel mottling and water fluoride concentrations was found.

Adolescent↗