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Biomedical subjects

M Doss

Publications and source records attributed to M Doss.

172 records · Page 10Linked to original sources

Over-production of porphyrins and heme in heterotrophic bacteria.

In Escherichia coli, Pseudomonas aeruginosa, and Achromobacter metalcaligenes gamma-aminolevulinic acid synthase and gamma-aminolevulinic acid dehydratase appear to be the rate limiting enzymes of porphyrin and heme biosynthesis. Bypassing of these enzymes by addition of gamma-aminolevulinic acid or porphobilinogen results in overproduction of tetrapyrroles.

5-Aminolevulinate Synthetase↗