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Biomedical subjects

M Donazzan

Publications and source records attributed to M Donazzan.

At least 37 records · Page 2Linked to original sources

[Risks and regulations related to materials used in implantology and maxillofacial surgery].

In the present paper, the authors call in mind the definitions of biocompatibility and the essential qualities required for biomaterials. The materials mostly used in implantology and maxillofacial surgery are numerous alloys, bioceramics, resorbable and non-resorbable polymers, and finally osseous substitutes of human or animal origin. As to synthetic and non-living materials, the risks in patients are generated by the degradation products. These may induce tissular reactions of inflammatory or immune origin owing to toxic effects. Concerning osseous substitutes, rejections are mostly of immune origin, for allografts and in particular for xenografts. Infections may be another major risk and in spite of all precautionary measures viral infections by hepatitis B, HIV and transmissible spongiform encephalopathy are not yet got under total control. It is just in these domains that one can state juristic lacks which national and european organisation of standardisation and homologation have to cover during the next few years.

Alloys↗

Evaluation of desmopressin for dental extractions in patients with hemostatic disorders.

We evaluated the effectiveness of desmopressin to control bleeding of patients with coagulation defects during dental surgery. Thirty-five patients, mainly with moderate and mild hemophilia and Willebrand disease, were undergoing dental extractions (over 80 extractions in total). Bleeding was successfully prevented in 28 patients with the use of a combined treatment incorporating IV desmopressin, an antifibrinolytic agent (tranexamic acid), and local methods (surgical glue and compression techniques). Seven patients had a bleeding episode after dental extraction, which was controlled in two cases by repeated injection of desmopressin and in another two by local methods; Factor VIII substitutive treatment was needed in only three patients. Desmopressin offers an alternative to blood products to control bleeding risk in patients with moderate and mild coagulation defects. Our experience tends to specify the mode of administration of both desmopressin and the associated treatments. Our findings suggest that desmopressin can be used in conjunction with other treatments to prevent bleeding in patients with coagulation defects who undergo dental surgery. This work highlights the concept of multifactorial medical care of these patients in which desmopressin plays a major role.

Adolescent↗

[The first clinical application of the vestibular orientation of the head using a scanner, in children presenting with asymmetry].

Digitalized imaging now allows determination the "medio-labyrinthic" plane to analyse cephalic symmetry. It is constructed from the two "vestibions", central points of the rings of lateral semi-circular canals. Reconstruction parallels this plane, passing through the vestibions provide vestibular orientation, with effective and constant coïncidence between right and left directions. That being obtained, it is easy to visualise orientation of the entire cephalic region in the three incidences of "vestibular space", and to work out sections parallels to the three vestibular planes, allowing analysis of the symmetry of the studied elements.

Cephalometry↗

[Maxillary ossifying fibroma: apropos of 3 cases].

Three cases of ossifying fibroma of the maxilla are reported in two young females and in one child. The characteristic of this benign fibro-osseous tumour are described. The authors insist on the necessity of a confrontation between the clinical, the radiological and the histopathological aspects of this tumour to establish a diagnostic.

Adult↗

[Indications and role of surgery in painful dysfunction syndromes of the masticatory apparatus].

Among the numerous causes of facial neuralgias, the painful dysfunction syndrome of the manducatory apparatus corresponds to a frequent etiology whose thorough study carried out by a multidisciplinary team over about 500 cases allowed their splitting into several evolutive clinical forms. At present, a number of these forms which are particularly painful, require a disk surgery (dislocation reduction, perforation suture, etc.) and if necessary an articular facet surgery (modelling condylectomy, surfacing, etc.). This study specifies the indications and prognosis for these surgical operations.

Facial Pain↗

[Arthrotomy for the permanent displacement of the temporomandibular meniscus. A coagulation-retraction technic of the posterior meniscal frenum].

An original technique for surgical treatment by arthrotomy for permanent closed lock of the temporo-mandibular joint is described. This technique uses the temporo-meniscal compartment approach. The superior belly of the posterior meniscal attachment is dissected and retracted by a diathermy coagulation. Advantages of this technique are compared to the usual techniques of meniscopexy and meniscorrhaphy using a suture. The indications are proposed.

Cartilage, Articular↗

[Arthrography of the temporomandibular joint].

In 1989, opaque contrast arthrography of temporomandibular joint is still seldom used. A brief historical review of the procedure is presented here, and the technique of puncturing the menisco-condylar and menisco-temporal compartments is discussed. The value of injecting opaque contrast material into the lower compartment and carrying out kinetic and tomographic studies as well as bilateral examinations is stressed. Normal aspects are described with their variants, as well as pathological ones (reducible and non-reducible luxations, perforations, distension of the bilaminar zone, adhesions, etc.). Both the place of arthrography in relation to other investigations (TDM, IRM) and its indications for visualization of menisco-condylar problems are discussed.

Arthrography↗

[Treatment of osteo-dural injuries of the anterior segment of the skull base through the trans-lesion approach. Apropos of 25 cases surgically treated by a dual neurosurgical and maxillofacial team].

The authors describe a technique of mobilisation of the frontal sinus using the fractures of anterior and posterior walls. The translesional approach is adapted to cranio-facial borders surgery of traumatisms. It's a skull base approach which minimizes the cerebral retraction and enables or perfect viewing of the top of the ethmoid. The advantages, drawbacks and indications are discussed about 25 cases.

Adolescent↗

[Contrast arthrography of the temporomandibular joint].

Seventy-four temporomandibular arthrographic examinations, mostly involving paracentesis of the menisco-condylar compartment, provided the means for visualizing normal and pathologic aspects of both reducible and non-reducible meniscal dislocations, and of perforations. Findings included distension of the bilaminar zone and adhesions. Post modeling condyloplasty status was noted. At present, arthrography seems to be the most reliable test, as well as being the easiest to perform and the least expensive one for visualizing menisco-condylar abnormalities.

Adolescent↗

[Adenoid cystic carcinoma of the salivary glands. Apropos of 52 cases].

52 cases of adenoid cystic carcinoma of the salivary glands are reported according to the age of the patient, to the localisation near an osseous structure or in soft tissues, to the histologic grade, to the therapeutic management, viz the surgical or radiotherapy treatment, correlated to the survival. It is worthy to notice that the localisations to the palate have a better prognosis than the localisations in soft tissues. Cribriform histologic grade in the same way have a better involvement than basaloid grade, but worse than tubular grade. Effectiveness of radiotherapy does not appear clearly in our study, unlike the observations of some authors.

Adolescent↗