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Biomedical subjects

M Dittgen

Publications and source records attributed to M Dittgen.

At least 37 records · Page 2Linked to original sources
PubMed1985

[The storage capability of pre-filled disposable plastic syringes].

The storage stability of a pre-filled plastic disposable syringe (piston type) of polypropylene as to solvents and ambient oxygen has been studied. To assess the permeability and impermeability of the sealing component parts, the syringes had been stored in a long-time test under different types of seal and different temperatures. Based on the results, the polypropylene plastic disposable syringes were on principal suited to be used in solvents as glycol, ethanol or water, the protection against ambient oxygen is, however, an insufficient one.

Drug Packaging↗
PubMed1981

[Studies on the reaction of plastics with drug solutions. Part 2: Nikethamide (author's transl)].

The authors describe the effects of nikethamide solutions of varying concentrations on natural-coloured and red-coloured low-density polyethylene. For this purpose, they analyse the findings from stress-crack studies performed by means of a test method previously described [6,7]. The results obtained lead to a new interpretation of pharmaceutical ageing under the given conditions.

Chemical Phenomena↗
PubMed1981

[Studies on the reaction of plastics with drug solutions. Part 3: The effects of the pigment content and of the colouring techniques (author's transl)].

The effects of the pigment content and of the colouring technique on stress-cracking are demonstrated by the example of the low-density polyethylene Mirathen A 13 EA. A 99% aqueous nikethamide solution was used as the drug solution. The sorption increased as the pigment content increased, which testifies to a relationship between the amount of the medium sorbed and the pharmaceutical ageing.

Adsorption↗