A method is presented for the detection of virus-host interactions at the chromosomal level. This method relies on the analysis of recombinant plasmids carrying specific regions of a viral DNA molecule. Human cytomegalovirus HindIII subgenomic fragments were used here as a target for recombination events.

Cloning, Molecular↗

PubMedDate not supplied

The effect of the inverted limbus on closed management of congenital hip dislocation.

A comparative study of 20 congenital dislocations of the hip with inverted limbus treated by closed reduction were compared with a group of 20 controls in which the limbus was non-obstructive as demonstrated by arthrography. In each group 3 hips developed signs of avascular necrosis. Seventeen of the 20 hips with inverted limbus and 11 of the 20 controls required subsequent femoral or acetabular procedures. Half of the hips in both groups at follow-up (mean 9 years) were dysplastic with a CE-angle of less than 20 degrees. Thus, the incidence of avascular necrosis and late clinical and radiographic results were comparable in both groups.

Child, Preschool↗