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Biomedical subjects

M Dietlein

Publications and source records attributed to M Dietlein.

85 records · Page 5Linked to original sources

Histological investigation for comparison of cartilaginous tumors of unknown biological course with unequivocal chondrosarcomas.

Morphological findings recorded from chondromatous tumors of unknown biological behaviour (n = 40) were compared with those obtained from unequivocal chondrosarcomas (n = 27), and the histological results were evaluated by clinical outcome. The morphological details were analysed by histological set up and summarized by Mirra et al. (1985): Two benign patterns, the enchondroma encasement pattern and the island of cartilage patterns, were the most common findings in cartilaginous tumors of unknown biological behaviour. Malignant patterns, such as chondrosarcoma permeation, invasion of the Haversian system, soft tissue mass and bands of fibrosis patterns were detected only in unequivocal chondrosarcomas. However, the enchondroma encasement pattern could be focally demonstrated also in central chondrosarcomas (n = 3), a phenomenon, which in our opinion could not be interpreted as being indicative of a preexisting benign lesion. Morphological classification of chondromatous tumors of unknown biological behaviour, as a group of benign cartilaginous tumors, enables their discrimination from unequivocal chondrosarcomas. This was also confirmed by the significant difference (p = 0.0065; Mantel-Cox) among survival curves after Kaplan and Meier (1958). We conclude that the above criteria, when applied with due caution, are helpful in classifying chondromatous tumors.

Bone Neoplasms↗

[Colonic contrast enema in digital luminescent radiography (DLR) and conventional x-ray technic].

120 double-contrast barium enemas were obtained by both digital luminescent radiography (DLR) and conventional screen-film systems, the digital exposure dose being 50% of the conventional one. In DLR two differently post processed images were obtained from one x-ray exposure: a display with low spatial frequency enhancement was processed to look like a conventional radiograph and was complemented by a display with high spatial frequency enhancement. Analysing the results statistically DLR proved to be diagnostically equivalent to conventional radiography despite the reduction in exposure dose and a slightly diminished image quality. High spatial frequency enhancement did not provide further diagnostic information and is therefore superfluous in barium enemas.

Adult↗

[Fibrous metaphyseal defect--a stage- and age-dependent differential diagnosis].

Based on 57 fibrous metaphyseal defects the conventional radiologic signs are described as diagnostically reliable including asymptomatic patients as well as patients with a history of pain and lesions with positive scintigraphy. The radiologic morphology of the fibrous endosteal and medullary defects differs with the age of the patient. Beyond the age of 18 years there is a sclerosis of the lesion and a less marked arrosion of the corticalis. The differential diagnosis depends on the cortical, endosteal of medullary site of the fibrous defect as well as on the age of patient and includes the cortical metastasis, the juxta-articular osteoid-osteoma, the periosteal chondroma, the cortical irregularity, the solitary bone cyst, the fibrous dysplasia, the chronic osteomyelitis and the osteosclerotic osteosarcoma.

Aging↗

[Juxta-articular osteoid osteoma--Image morphology and diagnosis].

Juxta-articular osteoid osteomas as a cause of persistent pain of the shoulder, elbow and knee are presented basing on three own observations and a review of the literature. The sequence of the imaging examinations is equivalent to the osteoid osteomas in other localisations. CT permits a clear presentation of the nidus in the complex juxta-articular anatomy. Juxta-articular osteoid osteomas often show an absent or small perifocal osteosclerosis, whereas a laminar periosteal reaction was seen in all own cases.

Adolescent↗

[Early diagnostic criteria of ankylosing spondylitis in patients with acute anterior uveitis].

A group of 59 patients with acute anterior uveitis (AAU) were examined for ankylosing spondylitis (AS) according to the New York criteria und criteria for early diagnosis of AS: 17/59 (29%) presented AS according to the New York criteria: a further 13/59 (22%) were classified as having incipient AS according to the early diagnosis criteria. These findings indicate that in a group of AAU patients there are, in addition to patients with definite AS, patients with initial AS though X-rays of the sacroiliac joints are still negative or equivocal. Early diagnosis criteria seem to be useful for identification of these patients at an early stage and can be used as a major selection criterion for monitoring programs.

Acute Disease↗

[Assessment of the grading of cartilaginous tumors of the long tubular bones from the radiologic and pathologic viewpoint].

Based on 46 enosteal cartilaginous tumours of the long tubular bones (43 patients) the established radiological and Mirra's histopathological criteria of tumour status are assessed independently and compared retrospectively. In lesions of Lodwick's type I B (37 cases) with mineralisation of the cartilaginous matrix and facultatively cortical arrosion, lack of periosteal reaction, destruction of the corticalis and parosseal tumour extension none of Mirra's histopathological criteria of malignancy was found. It may be expected that biopsy and histopathological examination will not give valuable additional information in this radiological constellation, because there are no known definite histopathological criteria of benignity. Suspicious radiological findings should prompt complete resection of the lesion. Biopsy and histopathological classification are always crucial when matrix mineralisation is lacking and therefore the diagnosis of a cartilaginous tumour cannot be established radiologically.

Adult↗

[Abdominal x-ray diagnosis using digital luminescent radiography--a comparison with conventional film-screen systems].

Abdominal x-ray examinations represent a variety of indications with different demands on exposure latitude, contrast resolution and spatial resolution of screen-film system combinations. The diagnostic value of digital luminescent radiography (DLR) was thus compared to conventional x-ray examinations carried out with screen-film systems, speed class 200, by analysing matched digital and conventional exposures in 46 abdominal and 25 pelvic x-ray examinations in supine and left lateral view, 156 contrast examinations of the gastrointestinal tract, 140 excretory urographies, 8 cholecystographies, 22 lymphographies and in 6 phlebographies. The digital exposure dose was 50% of the conventional one. In DLR two differently post-processed images were obtained from one x-ray exposure: a display with low spatial frequency enhancement was processed to look like a conventional radiograph and was complemented by a display with high spatial frequency enhancement. Analysing the results statistically, DLR proved to be diagnostically equivalent to conventional radiography despite the reduction in exposure dose and the lower digital spatial resolution. Since high spatial frequency enhancement did not provide further diagnostic information and eventually resulted in border line artifacts, high spatial frequency enhancement is superfluous in abdominal x-ray examinations.

Cholecystography↗

[Diagnosis of intramural hematoma of the colon].

Based on 7 of our own observations, the value of plain x-ray film of the abdomen, sonography, contrast medium diagnosis, and CT for diagnosing intramural haematomas of the colon is discussed.

Colonic Diseases↗