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Biomedical subjects

M Di Marco

Publications and source records attributed to M Di Marco.

14 recordsLinked to original sources
PubMed1998

Cell adhesion molecules in cord blood hematopoietic progenitors.

We investigated the expression of different cell adhesion molecules on cord blood (CB) and bone marrow (BM) CD34+/CD38+ and CD34+/CD38- cells. CD11a and CD62L were more expressed in CB than in BM CD34+/CD38- subset, suggesting a possible advantage in homing and engraftment. A short exposure to various cytokines increased CD62L expression only in the more differentiated CB and BM CD34+/CD38+ cells.

ADP-ribosyl Cyclase↗
PubMed1997

[Implanting of coronary stents in patients with unstable angina].

In the present study, we retrospectively examined our experience with the Palmaz-Schatz stent in patients with unstable angina to determine: a) different outcomes between patients with stable and unstable angina, b) correlation between the class of unstable angina and 1-month and 6-month results, c) correlation between lesion morphology and procedural complications. From January 1994 to January 1996, 160 patients with unstable angina (Group A) and 104 with stable angina (Group B) underwent coronary stenting. According to the modified Braunwald classification patients with unstable angina were divided into four classes. Lesion morphology was classified in simple and complex. Procedural success was 98% in Group A patients and 99% in Group B patients. We observed 9 (5.6%) major complications in Group A vs 2 (1.9%) in Group B. Subacute thrombosis occurred in 9 patients in Group A and in 2 patients in Group B and these different rates were responsible for the higher number of acute myocardial infarction and urgent revascularization procedures in Group A patients. At 6-month follow-up there were no differences between Group A and Group B patients. Patients in different classes of angina showed a similar cardiac event rate at 1-month and 6-month follow-up. We found 108 complex lesions in patients with unstable angina vs 20 in patients with stable angina (p = 0.0001). Among the 9 patients with unstable angina and subacute thrombosis, 6 had a complex lesion and 3 a simple lesion (NS). In conclusion, patients with unstable angina receiving intracoronary stent have similar clinical outcome at 1-month and 6-month follow-up as compared to patients with stable angina. The class of unstable angina and the complex morphology of the lesion are not related to procedural complications.

Angina, Unstable↗
PubMed1988

A technical aid in stapled esophagojejunal anastomosis.

A technique that allows a safer use of the pursestring applicator in stapled esophagojejunostomy is described. By means of five stitches, all esophageal layers are incorporated in the stapled line. Thus, missing a segment of esophageal mucosal layer is avoided. No clinical or radiologic leak was observed in 48 patients who underwent total gastrectomy using this technique.

Anastomosis, Roux-en-Y↗
PubMed1988

Abdominotransanal approach in the treatment of the low-lying rectal carcinoma.

Seven patients with non advanced cancer of the lower third of the rectum underwent sphincter-saving resection through a combined abdominoperineal approach. In this procedure not only coloanal anastomosis, but also bowel transection were performed through the anus. All the patients had cancer located between 3.5-5.5 centimeters from the anal verge. The main advantages of the technique are precise lines of bowel transection with desired distal clearance of tumor, and easier and safer mobilization of the distal end of the rectum during the abdominal phase of the procedure. No mortality was observed; morbidity was comparable to low anterior resection. The mean follow-up is 8 months and all patients are free of recurrence and continent.

Adenocarcinoma↗
PubMed1971

[Not Available].

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France↗
PubMedDate not supplied

[Percutaneous aortic valvuloplasty in the adult. When and why is now useful?].

Percutaneous aortic valvuloplasty was introduced into clinical practice in 1986 and widely applied in elderly patients with symptomatic aortic stenosis. Nevertheless its results have been unsatisfactory over the mid to long term due to a high incidence of restenosis after 6-12 months. At the same time, patients over 70 years are more frequently undergoing surgical aortic valve replacement with low immediate postoperative mortality and good long term results. Although randomized trials are not available, aortic valve replacement seems to be a definitive therapeutic treatment when compared to the palliative result of aortic percutaneous valvuloplasty. However, since the complication rate of valvuloplasty carried out in cardiological centers with experienced personnel is low, this procedure is still indicated in selected patients. The very old (> 80 years) patients with associated systemic disease, and candidates for major surgery are referred for this procedure. Another indication for aortic valvuloplasty is severe aortic stenosis with cardiogenic shock; in this case, valve dilatation improves clinical status and acts as a "bridge" to surgery, enabling surgical intervention to be carried out at a later date. Nowadays, aortic percutaneous valvuloplasty is a possible alternative to surgical treatment in patients with an absolute surgical contraindication and in those who are in such poor clinical condition that they cannot be immediately referred to surgery. It is also useful for patients requiring urgent non-cardiac surgery (e.g., subjects with gastrointestinal bleeding). We discuss our results with this procedure which concord with those presented in the literature.

Aged↗