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Biomedical subjects

M Di Fiore

Publications and source records attributed to M Di Fiore.

7 recordsLinked to original sources
PubMed1992

[Normovolemic induced hemodilution. Behavior of various hemodynamic indices].

Changes in mixed venous oxygen saturation of hemoglobin (SvO2), heart rate (HR), cardiac index, (SI) were measured in 20 patients undergoing major orthopedic surgery (rachis and pelvis bone resections for tumours: mean-lasting 8 hours), to estimate the safety limits during isovolemic hemodilution. Up to Hb 8 g%, in all patients, a cardiac index improvement (+41%) was found, and this was mainly caused by an increase in stroke index (+31%). For 16 patients at Hb 6 g%, this improvement was present only in 44% and declined during further hemodilution. In all cases, CI was moderately lower than baseline value (-18%) this was caused by an important increase in HR (= 55%) partially compensating for by the fall in SI (-57%). The Authors conclude that, in patients under general anaesthesia, isovolemic hemodilution is safe up to Hb 8 g%. Below this value the left ventricular performance rapidly declines.

Adult↗
PubMed1990

An ELISA method in the diagnosis of typhoid fever.

Anti-S. typhi IgG and IgM antibodies were detected by an ELISA test using whole S. typhi as antigen. Among sera of patients suffering from typhus, 100% were positive for IgG and 78.9% for IgM. In the control group (blood donors and patients with various diseases) positivities were 1.01% for IgG and 1.01% for IgM.

Antibodies, Bacterial↗
PubMed1989

[Antibodies against Toxocara canis in human serum from western Sicily].

335 human sera of western Sicily were examined with an ELISA method for the prevalence of antibodies anti-Toxocara canis. The results (13% pos. in psychiatric patients,9.4% in farmers, 1.9% in children and 1.2% in blood donors) seem to indicate a strong correlation between style of life and infestation risk.

Adult↗
PubMedDate not supplied

[Sodium naproxen in postoperative pain in orthopedics. Comparison of 2 different doses].

In order to use etiopathogenetic criteria for the treatment of postsurgical pain, non-steroid anti-inflammatory drugs (NSAIDs) can be used rather than narcotic analgesics. These agents are often classified as peripherally acting analgesic drugs; nevertheless in the last years many pages have who showed a central supraspinal analgesic effect. Sodium naproxen is commonly used in the treatment of postoperative orthopedic pain because of its pharmacokinetic properties. The aim of this study was to evaluate the suitable dosage of sodium naproxen for post-surgical pain relief. Forty patients submitted to foot surgery were randomized into two groups of 20 patients each. At the end of surgery one group of patients (group I) received sodium naproxen 275 mg i.m.; the same dose was administered after 12 hours. A second group (group II) received sodium naproxen 550 mg i.m. at the same time intervals. Based on a Descriptive scale for algometric measurements, the results showed significant differences in analgesic activity for the two treatments. The best results (70% of patients with no pain or slight pain vs 20% of patients) were obtained in the group that received sodium naproxen at the higher dosage (p less than 0.001). No differences were observed in the incidence of side-effects in the two groups. These results are discussed.

Adolescent↗
PubMedDate not supplied

Autologous blood pre-deposit in cemented hip arthroplasty.

The authors examine one of the methods used to avoid homologous blood transfusion in patients submitted to cemented hip arthroplasty. Although the series is not a numerous one (25 cases) it does show that even the pre-deposit of single unit of autologous blood is capable of eliminating the need for homologous blood transfusion in 96% of all cases.

Aged↗