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Biomedical subjects

M Delire

Publications and source records attributed to M Delire.

30 records · Page 2Linked to original sources

[Bacteremia and tonsillectomy].

A comparative study on the course of bacteremia and the postoperative behavior in 132 patients requiring tonsillectomy and adenoidectomy has been conducted. A control group including 33 patients was compared to three groups of an even number of cases treated with either doxycycline or amoxycyllin, or receiving gamma globulin immunotheraphy. Choice was guided by (1) the occurrence of bacteremia during surgery and the search for the various microbial strains involved, and (2) the confirmation of the advantages of the drug used within the first week of treatment.

Adenoidectomy↗

HLA gene and haplotype frequencies in spina bifida. Population and family studies.

The search for HLA association in spina bifida is particularly interesting since this condition can be associated with the effects of the T locus in mice. Gene and haplotype frequencies in 32 unrelated patients suffering from spina bifida were studied. Gene frequency of HLA-B5 and haplotype frequency of A2, B5 were increased without reaching signification levels. Fourteen families were examined clinically and radiologically. A high frequency of spina bifida occulta and other vertebral abnormalities was found without evidence of linkage with HLA haplotypes.

Adolescent↗

The detection of circulating immune complexes in children with recurrent infections and their treatment with human immunoglobulins.

In a study of thirty-nine children with recurrent infections, circulating antigens, either free or in the form of immune complexes, were detected in thirty. The ability of sera to inhibit the agglutination of latex by rheumatoid factor or the C1q component of complement was used as a test for the presence of immune complexes. The children were treated by three injections of the same preparation of human immunoglobulin as that used for the serological tests, and a marked and sustained improvement in twenty-one patients was observed. In nineteen of these, circulating antigens reacted in vitro with antibodies in the immunoglobulin preparation, whereas of the eighteen children who did not improve with treatment, the sera of thirteen failed to react in vitro with the immunoglobulin preparation.

Antigen-Antibody Complex↗

[Use of clobazam 20 mg in general practice].

Fifty practitioners treated 224 patients with clobazam for 4 weeks. The anxiolytic action, the tolerability, the degree of satisfaction and the dosage of clobazam were evaluated by means of a modified "Rating Scale for Anxiety" by Hamilton and self-evaluation scales. Clobazam proved to have an important anxiolytic activity together with good tolerability. The ability to concentrate was remarkably improved, which seems to confirm the specificity of the molecule (benzodiazepine-1,5). The reduction of anxiety and of anxious equivalents and the good tolerability of the product were confirmed by the judgement of satisfaction of the doctors as well as of their patients.

Adolescent↗