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Biomedical subjects

M Delecour

Publications and source records attributed to M Delecour.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Epidemiologic data on arterial hypertension in pregnancy].

A retrospective study of 241 case histories of essential hypertension in pregnancy treated in the Salengro Maternity Hospital of Lille from 1976 to 1981 was carried out. Looking at 450 readings of blood pressure in pregnancy it has been possible to work out a profile for these patients. These patients have as singular factors: They are often fat or very fat. They often have raised cholesterol levels in the blood. They often have a family history of hypertension or of diabetes. Many use oestro-progestogen birth control pills and had trouble in glucose regulation far more than women who had normal blood pressures in pregnancy.

Adult↗
PubMed1984

[Medullary compression due to vertebral angioma in pregnancy. A case treated by embolization].

A previously healthy 24 year old woman presented a progressive paraplegia during the third trimester of her second pregnancy. Partial improvement occurred after caesarian. The neuroradiological study revealed spinal cord compression by an extensive corporeo-pedicular angioma of the T2 vertebrae. Almost total recovery occurred after selective embolization. The occurrence of neurological complications of vertebral angiomas during pregnancy is rarely reported in the literature. Mechanisms of the spinal cord compression and their relations with the pregnancy are discussed and difficulties for diagnosis and treatment are emphasized. When technically possible, the embolization appears to be the most adapted treatment, especially for these extensive types of vertebral angioma.

Adult↗
PubMed1983

[Prolonged fetal monitoring, ultrasonic telemetric registering. Methodology. Applications].

Studying the fetal heart rate is the method of choice for monitoring fetal wellbeing. All the same, when repeated records are made, but only over a short time, no permanent control is carried out and this means that some very high risk fetuses are not monitored properly. but all these involved using electrocardiograms to record the fetal heart rate and this was not a practical proposition because of the number of artifacts that were produced. the authors suggest using a new method of observing the fetal heart rate over a long period of time based on telemetric transmission of the rate using an ultrasound machine. They show the results and also the difficulties of using this apparatus as well as the prospects for studying fetal physiology in this way.

Female↗
PubMed1983

[The unruptured luteinized follicle. Determination of estradiol and progesterone in peritoneal fluid].

The finding of more luteinized unruptured follicles in women who are under investigation for unexplained infertility compared with fertile women suggests that the syndrome does exist and probably plays a causative role in the infertility of these patients. The levels of oestradiol 17-beta and progesterone found in the peritoneum in the early luteal phase showed a much higher figure when there has been rupture of the follicle with a haemorrhagic corpus luteum and a stigma as compared with luteinized unruptured follicles. It does seem to us worth while to obtain some of the peritoneal fluid in order to estimate the levels of hormones and to diagnose more often the unruptured follicle syndrome whenever laparoscopy in undertaken in the early luteal phase.

Body Fluids↗
PubMed1983

[Thrombo-embolic disease of pregnancy. Methods and indications for surgical prevention].

Thrombo-embolic disease can generally benefit from anticoagulant treatment. Nevertheless, there are circumstances that require surgical prevention of pulmonary embolism. The vena caval circulation can be interrupted using clips, which necessitates a general anaesthetic and laparotomy, or intravenous procedures such as Mobin-Udin or Greenfield filters may be inserted. The indications for these procedures depend on how advanced the pregnancy is. The authors point out the indications for interruption of the vena caval flow during pregnancy in the light of four recent case histories. The main one is failure of medical treatment. Interruption of the vena caval flow is to be recommended when there is impaired circulation or when a thrombus is threatening. The diagnosis of this condition does require invasive tests; and whether these are toxic for the fetus is discussed.

Adult↗
PubMed1982

Quantitative bacteriological analysis of amniotic fluid.

Quantitative bacteriological analysis of amniotic fluid (AF) was performed on 60 fluid samples collected by catheter from 50 selected labor patients regarded as liable to infection. AF cultures were positive in 52 cases. The bacterial colony counts ranged from less than 10(2) colony-forming units (CFU) per milliliter to 10(9) CFU/ml. Pathogenic bacteria in neonates such as group B Streptococcus, Escherichia coli, and Listeria monocytogenes were encountered with numerations equal to or greater than 10(7) CFU/ml in groups with clinical findings. An excellent correlation was noted between bacterial counts in AF and clinical data (p less than 0.00006). The results confirm that the quantitative bacteria analysis of the AF is a useful tool for evaluation of an infection risk for neonates.

Amniotic Fluid↗
PubMed1982

[Transfer of neonates in northern france. Factors of mortality (author's transl)].

An extensive study was undertaken in northern France from January 1st to May 31st 1978, concerning the transfer of neonates from maternity hospitals to specialized units. Analysis of 250 children whose birth weight was below 2,000 gm showed that several risk factors could be taken into account to reduce neonatal mortality in this area. Prematurity (22% children weighing less than 1,500 gm in those discharged alive, 54% in the dead), neonatal distress (36% versus 61% of resuscitation) hypothermia (7% versus 23% with temperature below 34 degrees 6 at the time of admission), the need for an other transfer (1% vs. 12%) seem to be features highly related with poor prognosis. This stresses the importance of the prevention of prematurity, of proper management of the babies in the maternity hospital, of the conditions of transport and of the choice of the neonatal unit.

France↗
PubMed1982

[Problem in echographic diagnosis: intrauterine pseudo-sac].

The authors report eight cases of an intra-uterine pseudo-sac giving a wrong diagnosis of intra-uterine pregnancy. In two cases there was hypertrophy of the uterine mucosa and in six cases there was decidual change. The pseudo-sac corresponds to: either a blood clot held by the uterine mucosa; or a marked hypertrophy of the endometrium with intense decidualization and massive oedema. Certain characteristic criteria suggest that a pseudo-sac may be in the uterus; the oblong shape, dimensions which do not accord with the period of amenorrhoea, absence of peripheral and linear thickening, the variety of sites in which the picture is seen and in particular its disappearance, which makes it difficult to localise it in all sections. On the other hand it is not possible to diagnose between an intra-uterine pseudo-gestational sac and an early intra-uterine pregnancy which is not growing, in our present state of knowledge.

Diagnostic Errors↗
PubMed1982

[Postpartum renal cortical necrosis].

The authors report two cases of post-partum cortical renal necrosis. The diagnosis was made on clinical and biological criteria (severe, prolonged oliguria, the signs of intra-vascular coagulation defects, a rise in L.D.H. and anaemia with micro-angiopathy. It is confirmed by selective renal arteriography and renal punch-biopsy. There is a threefold method of treatment: --of the kidney condition by repeated haemodialysis and diuretics; --antihypertensive treatment; --treatment aimed at the aetiological pathology (heparin, anti-platelet aggregation and fresh plasma). Functional recovery of the kidney was obtained in both cases (after an interval of 1 year and an interval of 1 1/2 year). The authors review the diagnostic, physiopathological, morphological and therapeutic elements in the condition of cortical renal necrosis.

Adult↗
PubMed1982

[Ectrouria. Apropos of a case].

Report of a case of sirenomelia (mermaid) anomaly. This male fetus was born from a 30 year-old mother and remained alive for 18 hours. The following anomalies were present: Potter's syndrome, absence of external genitalia and internal genital ducts, presence of two male gonads, renal agenesis, lack of bladder and ureteral ducts, single umbilical artery. Were also found: right radial dysplasia, Fallot tetralogy, T.E. fistula with esophageal atresia, lumbo-sacral spina bifida cystica.

Abnormalities, Multiple↗
PubMed1981

[The value of estimating the levels of amniotic insulin which come from the fetus in looking after diabetic pregnancies in the last trimester (author's transl)].

The authors carried out 49 estimations of amniotic fluid levels of insulin in 41 patients. 25 of these patients were non-diabetic and they were a control group, and 16 patients were diabetic (24 estimations). The liquor was collected by amniocentesis between the 32nd and the 42nd week of amenorrhoea. The mean of the control levels was 3.17 micro-units per ml. The mean of the values in diabetic pregnancies was 9.97 micro-units per ml. The difference between the two groups is statistically significant. We have studied this insulinaemia in relationship to the duration of the diabetes, the maternal weight increase, the levels of insulin used therapeutically, the blood glucose level, the rise in arterial blood pressure, the weight of the infant, the date of delivery, the presence of fetal distress and the control of blood sugar. There is a statistically significant difference between the insulinaemia of patients in whom the diabetes is well controlled (mean level of 7.08 micro-units per ml) and the patients in whom the diabetes is badly controlled (31.7 micro-units per ml). This new parameter for supervision of the third trimester of pregnancy in diabetics gives rise to the possibilities of a better approach to materno-fetal blood sugar regulation and to an adjustment of the therapeutic doses of insulin that are given which will result in lengthening of the duration of pregnancy, with the aim of achieving a spontaneous vaginal delivery at term.

Amniocentesis↗
PubMed1981

[The level of glycohaemoglobin (Hb A1c) in connection with diabetes and pregnancy (author's transl)].

The authors worked out a normal curve using 379 levels obtained over 9 months in 180 normal pregnancies. 6% (with a confidence level between 4.4% and 7.6%) was usual for haemoglobin A1c. Then they compared 42 levels of glycohaemoglobin obtained from 14 pregnant diabetic patients where the mean value was 8.34%. Glycohaemoglobin A1c therefore is a good indicator or the level of stabilisation in diabetic pregnancies in the two months before the estimation is taken. It is therefore possible to think that it does indicate chronic hyperglycaemia and does seem to have a future in screening diabetic pregnancies. On the other hand it does not seem to be of any supplementary value in monitoring the fetus of the diabetic mother in the third trimester of pregnancy because of the small variations in the levels that are obtained as compared with the suddenness of fetal complications.

Birth Weight↗
PubMed1979

[The prognostic value of raised uric acid in the blood in arterial hypertension in pregnancy. 58 cases (author's transl)].

The authors have carried out research in 58 cases to see whether the findings of high uric acid levels in the blood are of prognostic value in all cases of arterial hypertension in pregnancy whatever the aetiology. The material studied consisted of 30 true cases of toxaemia of pregnancy, 13 cases of recurrent toxaemia and 15 cases of the vasculo-renal syndrome on top of the pre-existing pathological condition. In 37 cases where the blood uric acid level was lower than 300 micromoles there were only 4 minor complications. Serious complications were found in 6 cases in which the patients had a blood uric acid level highthan 480 micromoles. This study confirms the prognostic value of blood uric acid levels. The estimation of these levels, however, seems to be of less value in making a differential diagnosis between the various kinds of toxaemia and hypertension found in pregnant women due to different aetiologies.

Adult↗