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Biomedical subjects

M Degeorges

Publications and source records attributed to M Degeorges.

At least 91 records · Page 5Linked to original sources

Myocardial scintigraphy with technetium 99m pyrophosphate.

The pyrophosphate of Tc99m attaches itself to ischaemic myocardial cells, and therefore makes it possible to obtain a scintigram of necrotic or necrosing myocardium. In a series of 65 cases the scintigram was positive in every case in which there had been a recent transmural infarct (17 cases). The results showed greater variation in the other ischaemic conditions involving the myocardium (limited infarcts or simple angina). The progress as a function of time was stuided in a series of fairly recent and older infarcts. The limitations and future prospects of this investigations are discussed.

Coronary Disease↗

[Scintigraphy of the myocardium following injection of thallium 201 during an exercise test. Value in the study of myocardial ischemia].

Thallium 201 is fixed rapidly by the healthy mocardium, and its emissions are easily recordable with a scintillation camera; it was used to discover and localise zones of ischaemia. This radio-isotope was injected into 40 patients during an exercise test. The results from this so-called exercise scintigraphy were compared with those of the exercise ECG, with the findings on coronary arteriography in 32 cases, and in 14 cases with those obtained by injecting thallium 201 into the patient while at rest (the so-called scintigram at rest). The results obtained from exercise scintigraphy correlate well with those from the exercise ECG and coronary arteriography. It would seem to have an important place in monitoring the permeability of aorto-coronary bypasses.

Coronary Disease↗

[Treatment of Laubry-Pezzi syndrome apropos of a case in a 7-year-old child].

Report of one case of a Laubry and Pezzi syndrome. In spite of the already severe aortic incompetence at the age of 4 years, operation was postponed. Three years later, at the first signs of bad tolerance of the aortic incompetence the operation was undertaken including: -- closure of the ventricular septal defect by a patch, and correction of aortic incompetence by a metallic-ball Starr's prosthesis n 9. After an observation period of 18 months, the result of operation is satisfactory, in spite of signs of haemolysis. Comparison with the data from the literature led to the following conclusions: 1) in a patient with ventricular septal defect the demonstration of a diastolic murmur indicates closure of the septal defect. 2) When the aortic incompetence is a severe one, it should be corrected urgently, whatever the age of the child, if badly tolerated. In the very young child, if it is well tolerated, the operation might be postponed in view of the difficulties of plastic operations and the hazards of prostheses in such patients. 3) A moderate aortic incompetence constitutes the most difficult indication; a conservative operation seems to be preferable to a valve replacement by a prosthesis, a homograft or a heterograft. The results obtained by some techniques of valvular plasty after observation periods amounting to 12 years are considerable.

Aortic Valve Insufficiency↗