[Staged reconstruction of the pharynx and esophagus].
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Esophagoplasty↗
Biomedical subjects
M De Silva
Publications and source records attributed to M De Silva.
Long-term azathioprine in rheumatoid arthritis: a double-blind study.
Several studies have demonstrated the beneficial effect of azathioprine in rheumatoid arthritis. But fears have been expressed about the possible mutagenic and teratogenic effects of prolonged use. If the drug could be withdrawn once remission is achieved, and this remission be then maintained with other agents, the possible complications of long-term therapy might be avoided. A double-blind controlled study was carried out over 8 months in 32 patients receiving long-term azathioprine therapy for rheumatoid arthritis. Substitution of placebo for active drug resulted in clinical deterioration.
Adult↗
Haemophilus paraphrophilus endocarditis in a prolapsed mitral valve.
A case of Haemophilus paraphrophilus endocarditis successfully treated with ampicillin is described. The patient, a 24-year-old woman, had a prolapsed mitral valve. The organism was initally misidentified as H. parainfluenzae, which it closely resembles. H. paraphrophilus is distinguished by its requirement of 10% CO2 for growth on NaCl-free medium and its inability to ferment xylose.
Adult↗