Determination of organ volume by single photon emission tomography.
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Biomedical subjects
Publications and source records attributed to M Dahlborn.
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The effect upon blood coagulation and aggregation of platelets of a polysaccharide catheter flush fluid (flush fluid E) was investigated and compared with isotonic saline and Isopaque Cerebral. The result indicates that flush fluid E does not activate the coagulation system.
Using an experimental model of the arterial circulation system, inflow of blood into polyethylene catheters following injection of contrast medium and isotonic saline solution was evaluated. The experiments included an analysis of the influence of density and viscosity of the flush solutions as well as the effect of catheters of different sizes with and without sideholes.
Inflow of blood into intraarterial catheters in dogs following single and continuous injections of saline, contrast medium and polysaccharide fluids were analysed with special reference to the influence of their density and viscosity. Clot formation was also analysed and the favourable properties of one variant of the polysaccharide fluids were demonstrated.
Bone scanning of the spine and the anterior thorax was performed in 5 girls with recently diagnosed, progressive, thoracic, idiopathic scoliosis. In all patients, the scan of the spine showed a homogenous isotope uptake which was considered to suggest that, at least during the early stages of the development of the spinal deformity, there are no obvious disturbances of the metabolic activity of the affected vertebrae in idiopathic, thoracic scoliosis. On the contrary, in all patients there were differences in isotope activity between ribs on the left and right side at the costochondral area. In 4 of the patients, the higher uptake was found in the ribs on the concave side, which might indicate that the longitudinal growth of the ribs on this side was increased as compared with that of the ribs on the opposite side. Because of the restricted number of patients allowed to be included in this study, this observation could not be verified statistically and has to be considered preliminary, in need of verification as well as of further investigation.
Using an experimental model of the arterial system, inflow of blood into polyethylene catheters following injection of two contrast media, isotonic and hypertonic saline solutions was investigated. The experiments included an analysis of the influence of the density of the solutions and the orientation of the catheter as well as the effect of single fluid injection and continuous flushing of the catheter.
Inflow of blood into intra-arterial catheters following injection of contrast medium into the common carotid artery in patients and into the aorta in dogs is investigated. Influence of form and orientation of the catheter in the vessel and the effect of constant flushing are determined as well.
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Computer tomography (CT) presents a method of determining longitudinal axis vertebral rotation and vertebral, spinal, and rib case deformity. Different rotation angles, distances, and indexes are defined and discussed. Radiation risks were evaluated and considered exceedingly small when compared to the ordinary spinal anteroposterior radiograph. In a model study the mean difference between actual vertebral rotation and measured rotation was 0.3 degrees if the vertebrae were tilted up to 20 degrees in either the frontal or sagittal plane. This accuracy was lost if the vertebrae were tilted 20 degrees in both the frontal and the sagittal plane. Computer tomography can be used for evaluation of the vertebral rotation in the frontal plane.
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The correlation between the lateral curve, the location and the length of the curve, and the longitudinal axis rotation of the apical vertebra has been studied in 65 patients with idiopathic scoliosis using computer-assisted tomography. This method provides the opportunity to describe the relationship between the rib hump, the longitudinal axis rotation, the lateral curve, and the kyphosis-lordosis with exceedingly small radiation doses. The vertebral rotation was found to be correlated to the lateral curve but not to the location of the length of the curve. The longitudinal axis rotation of the vertebrae is the most important factor for the development of the rib hump which is further accentuated by increased lordosis.
The effects of Harrington instrumentation on the longitudinal axis rotation of the vertebra, the kyphosis-lordosis, and the rib-cage deformity were investigated by computer tomography in 33 patients. No significant derotation was achieved. The sagittal diameter of the rib cage was reduced significantly with distraction rod instrumentation and further by additional application of a compression rod. The rib hump was reduced significantly only with distraction rod instrumentation. The obtained results indicate that despite instrumentation, the spine preserves an almost unchanged peripheral position in the rib cage.