The exposition as a marketing strategy.
Explore the source record for details and available documents.
Exhibitions as Topic↗
Biomedical subjects
M D Weiss
Publications and source records attributed to M D Weiss.
Relocating families. An overlooked market segment for nursing.
Occupational health nurses are capable of supporting the coping skills of families during relocations. However, nurses must "market" this expertise to human resource personnel. Relocation affects the family's ability to adapt to stress, disruption of health care provider service, child care for working parents, and continuity of care for chronic health problems. Encouraging planning, effective goal setting, and efficient time management skills can augment coping strategies.
Adaptation, Psychological↗
Primary small cell carcinoma of the paranasal sinuses.
An unusual case of small cell carcinoma of the ethmoid sinuses is reported in which electron microscopy confirmed the presence of dense-core granules. The relationship to Pearse's "neuroendocrine programmed" cells is cited. With increasing numbers of different extrapulmonary primary sites for this tumor now being identified, it is believed that these sites must be investigated in any case of suspected small cell carcinoma that cannot be readily attributed to the lung.
Aged↗
Tracheal involvement in laryngeal papillomatosis.
A review of 39 laryngeal papilloma patients at The Johns Hopkins Hospital revealed an incidence of subglottic and tracheal extension much higher than previously reported. Subglottic disease was present in 69% of patients and tracheal involvement in 26%. Factors associated with distal spread were the presence of subglottic papillomas, history of tracheostomy, total number of endoscopic resections, and the duration of disease. The relationship to the presence of viral antigen was cited. Detection and elimination of all papillomas is felt to be the key for the prevention of distal spread. The strategy of management is described.
Adult↗
Implementing total quality management and reshaping delivery systems in a community hospital.
In today's healthcare marketplace, leadership requires more than the delivery of technologically sophisticated patient care. Leadership can be accomplished only by an organization energized with a mission that focuses on providing high-quality, technologically sophisticated, and cost-effective primary healthcare. The paradigm shift to total quality management at the authors' not-for-profit community hospital involved not only the adoption of the philosophy, tools, and techniques espoused by quality experts, but also a restructuring of the organization from a hierarchical format to one focused on the patient.
Community-Institutional Relations↗
Glutamine synthetase: a key enzyme for intestinal epithelial differentiation?
BACKGROUND: We have previously shown that glutamine synthetase protein and mRNA are concentrated in the crypt region of the rat small intestine and that the activity of this enzyme is highest around the time of weaning. This anatomical location and time of peak activity are sites and periods of active enterocyte differentiation. This led to our current hypothesis that glutamine synthetase is important in the differentiation of enterocytes. METHODS: To test our hypothesis, we treated Caco-2 cells with physiologic (0.6 mM) glutamine concentrations in cell culture medium. The experimental group was treated with methionine sulfoximine, an irreversible glutamine synthetase inhibitor, and the control group with phosphate buffered saline. Three standard and well-defined markers of intestinal differentiation-sucrase-isomaltase activity, microvillus formation, and electrical impedance in transwell plates-were compared between the two groups. RESULTS: The methionine-sulfoximine-inhibited group was found to have lower sucrase-isomaltase activity, a lower density of microvilli, and lower electrical impedance values over time compared with the control group. CONCLUSION: The experimental group was found to be less differentiated by all three markers of differentiation. Therefore, glutamine synthetase is important for Caco-2 cell differentiation.
Caco-2 Cells↗
Necrotizing enterocolitis: pathophysiology and prevention.
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in the neonatal intensive care unit. It is a disease of medical progress in that more very low-birth-weight neonates are surviving than ever before and are thus susceptible to this potentially devastating disease. NEC received very little attention in the literature before the 1970s but now is well known to all neonatologists and pediatric surgeons. The 1500 to 2000 infants that die every year from this disease in the United States and the large number of infants who develop short gut syndrome from this disease only represent the tip of the iceberg of the problems NEC causes. The widespread fear of NEC among neonatologists and pediatric surgeons has contributed in large part to the use of the IV route rather than the gastrointestinal tract for nourishing these infants for relatively long periods. The consequences of this include a high incidence of sepsis, high hospital costs, and potential long-term neurodevelopmental disability because of poor nutrition during a very vulnerable period of growth and development. The purpose of this review is to provide a brief overview of the clinical presentation and current treatment for NEC, then provide a discussion of the pathophysiology on which strategies for prevention can be formulated.
Enteral Nutrition↗