Fatal rabies encephalomyelitis despite chick embryo vaccine prophylaxis.
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Biomedical subjects
Publications and source records attributed to M D Shah.
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Malignant hypertension in an adolescent due to reflux nephropathy (RN) is rare. Here we are presenting such a case unassociated with the usual symptoms of hypertension. The problems of diagnosis, management, prognosis and prevention of RN are discussed with a review of relevant literature.
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A case of tetralogy of fallot with congenital intermittent atrioventricular dissociation is reported. A review of standard postgraduate books of cardiology fails to describe this condition, thus showing its extreme rarity. The therapeutic dilemma in treating such a case is also discussed.
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A 6 1/2 year old female child with congenital lipodystrophy is being presented. The noteworthy feature in this case was the defective leucocyte function and its association with tuberculous pericardial effusion.
Twenty-three neurologically normal children with focal convulsions were studied with EEG and CT scan. Thirty-five per cent had an abnormal CT scan. Lesions of potential therapeutic significance were seen in 30 per cent of all scans. Abnormalities detected on CT scans were as follows: tuberculomas, five cases; acute infarct, one case; gliosis, one case; multiple cortical cysts, one case. All the cases with intracranial tuberculomas were aged more than 5 years. A good correlation was found between the EEG and the CT scan findings. Maximum percentage (57 per cent) of CT scan abnormality was seen in cases exhibiting focal abnormality on EEG and minimum percentage in those with a normal EEG (18 per cent).
The efficacy of enzyme-linked immuno-assay in the detection of IgG antibody against mycobacterium tuberculosis in the cerebrospinal fluid of patients suffering from tuberculous meningitis was measured in 50 children consecutively admitted to hospital. The controls were 15 cases of tuberculosis other than of the central nervous system; 24 cases of pyogenic meningitis; 19 cases of neurologic problems but with essentially normal cerebrospinal fluid. The specificity of the test ranged from 93 to 100 per cent and the sensitivity from 82 to 95 per cent.
Over a period of 1 1/2 years, 9 infants ages ranging between 3 weeks and 7 months presented with the syndrome of late hemorrhagic disease related to vitamin K deficiency. All were exclusively breast fed and had not received vitamin K at birth. Four of these had acute intracranial hemorrhage, of which 2 expired and the surviving 2 have residual neurologic handicap. Of the remaining 5 who had skin and mucosal bleeds, all recovered on administration of vitamin K.
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