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Biomedical subjects

M D Rosin

Publications and source records attributed to M D Rosin.

8 recordsLinked to original sources

Successful operation in an old survivor of anomalous origin of the left coronary artery from the pulmonary trunk (Bland-White-Garland syndrome).

A case of anomalous origin of the left coronary artery from the pulmonary trunk is reported. The patient, a 64-year-old woman, presented with a history of angina and cardiac failure. She was known to have had a mitral systolic murmur since school age. Echocardiography showed clinically significant mitral regurgitation and highly unusual extensive calcification of the mitral valve chordae, papillary muscle, and posterior left ventricular wall--a pattern suggesting the possibility of abnormal coronary circulation. Subsequent cardiac catheterisation confirmed considerable mitral regurgitation with a dilated left ventricle, and arteriography confirmed anomalous origin of the left coronary artery from the main pulmonary trunk. The patient was surgically treated with ligation of the origin of the anomalous left coronary and mitral valve replacement. She was alive and well 2 years after operation.

Cardiac Catheterization

Galactorrhoea following surgical procedures to the chest wall: the role of prolactin.

Normal prolactin levels were found in two cases of galactorrhoea following surgical procedures to the chest wall and one was treated successfully with bromocriptine. Studies were then carried out to test the claim that chest-wall injury is one of the common causes of hyperprolactinaemia. Serum prolactin levels were measured before and after thoracotomy in 7 patients, following traumatic rib fractures in 8 patients and after burns to the chest in one patient. No evidence was found to suggest that sustained hyperprolactinaemia follows chest wall surgery or injury, and the role of prolactin in the condition 'chest wall injury' galactorrhoea is discussed.

Adolescent