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Biomedical subjects

M D Jones

Publications and source records attributed to M D Jones.

At least 181 records · Page 10Linked to original sources
PubMed1977

The effect of cuff width on systolic blood pressure measurements in neonates.

The width of the blood pressure cuff was found to have an effect on the accuracy of systolic blood pressure measured in the arm and thigh in neonates. Data were collected in 26 infants of a variety of birth weights and gestational ages. They show that the effect of cuff size can be minimized by selecting a cuff width equal to approximately 50% of the extremity circumference.

Arm↗
PubMed1977

Cervical spinal stenosis.

Cervical spinal stenosis occurs at the craniovertebral junction, usually incident to a congenital malformation, or it appears as a developmental defect with diffuse narrowing of the cervical canal. In its acquired form the lesion may be limited to one or two levels, or it may be more extensive and affect three or more segments.

Adult↗
PubMed1977

Lumbar spinal stenosis.

Recognition and management of problems inherent in spinal stenosis require a clear understanding of the diverse anatomic changes, their radiologic representations, and careful correlation with a wide spectrum of fluctuating clinical manifestations. Although a common basis might be postulated for narrowing of the spinal canal, emphasis should be placed on its various forms.

Achondroplasia↗
PubMed1977

Lumbar spondylolisthesis with isthmic defects.

The importance of spondylolisthesis, aside from the obvious malalignment and malformation of the affected vertebrae, rests mainly on the possibility and the extent of impairment of activity. In this discussion the authors are concerned mainly with the myelographic signs associated with spondylolisthesis in patients with isthmic changes.

Adult↗
PubMed1977

Degenerative spondylolisthesis with an intact neural arch.

Whereas the skeletal, anatomic, and clinical aspects of this condition have been scrutinized in detail, the radiologic changes have received less attention. In this discussion the plain film changes are briefly reviewed, and emphasis is directed toward the myelographic manifestations that reflect intraspinal and intraforaminal instrusions and their clinical sequelae.

Adult↗
PubMed1976

Umbilical uptake of amino acids in the unstressed fetal lamb.

The whole blood concentrations of 22 amino acids were measured in a chronic, unstressed fetal lamb preparations. Samples were taken daily from the umbilical artery, umbilical vein, and maternal artery over the latter quarter of gestation. 73 sets of samples (from the umbilical artery and vein and the maternal artery) from 13 animals were analyzed for amino acid levels. Oxygen contents were determined simultaneously in 48 sets (umbilical artery and vein) to relate fetal oxygen consumption to amino acid uptake via the umbilical circulation. The results indicate that there is no umbilical uptake of the acidic amino acids, glutamate and aspartate; there is, in fact, a net flux of glutamate out of the fetus into the placenta. As both of these amino acids are major constituents of body proteins, the data indicate that they are formed within the fetus. The umbilical uptake of some neutral and basic amino acids (e.g., valine, leucine, isoleucine, arginine, phenylalanine, and tyrosine) is in considerable excess of estimated growth requirements, suggesting that some amino acids undergo extensive transamination and oxidative degradation in the fetus. Finally, the net uptake of nitrogen, carbon, and calories by the growing ovine fetus in the form of amino acids, glucose, and lactate is compared to estimated requirements as determined in previous studies.

Amino Acids↗
PubMed1975

Failure of association of premature rupture of membranes with respiratory-distress syndrome.

Records on 16,458 consecutive births were examined to determine associations between the respiratory-distress syndrome of the newborn and cesarean section, maternal diabetes, ante-partum hemorrhage, toxemia of pregnancy, low one-minute Apgar scores and prolonged rupture of fetal membranes. Groups of infants were compared by four-week gestational age blocks. One-minute Apgar scores of less than 5 and of less than 8 were associated with a significant ( less than 0.05) increase in the incidence of respiratory-distress syndrome at gestational ages beyond 30 weeks. Cesarean section was associated with a significant increase after 34 weeks of gestation. There was no association between the syndrome and toxemia of pregnancy, ante-partum hemorrhage or prolonged rupture of fetal membranes. These data do not support the hypothesis that there is a lower incidence of the respiratory-distress syndrome in infants born after prolonged rupture of fetal membranes.

Apgar Score↗
PubMed1975

Cerebral metabolism in sheep: a comparative study of the adult, the lamb, and the fetus.

The cerebral uptakes of glucose, oxygen, lactate, pyruvate, acetoacetate and beta-hydroxybutyrate were compared in the adult, the fetal, and the newborn sheep. Beginning 1-2 days after surgery, we withdrew samples simultaneously from an artery and from the sagittal sinus for up to 2 wk. At all ages glucose was the only substrate taken up in significant quantity relative to oxygen. The glucose-oxygen quotients were 0.98 less than 1.03 less than 1.08 in adults; 0.92 less than 0.99 less than 1.06 in lambs; 0.92 less than 0.98 less than 1.03 in fetuses. These quotients were not significantly different. There was a significant (P less than .05) arteriovenous difference for lactate in the adult (-0.031 mM), but not in the lamb or fetus. A significant (P less than .05) arteriovenous difference pyruvate was found in the adult (-0.013 mM) and in the fetus (-0.020 mM). The findings of a glucose-oxygen quotient of approximately 1 and the lack of significant lactate production in fetal sheep brain are consistent with the hypothesis that anerobic glycolysis is unimportant to the steady-state cerebral metabolism of the fetal sheep.

Acetoacetates↗