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Biomedical subjects

M D Cheitlin

Publications and source records attributed to M D Cheitlin.

At least 127 records · Page 7Linked to original sources
PubMed1975

Myocardial infarction without atherosclerosis.

By far the most frequent pathologic condition preceding myocardial infarction is coronary atherosclerosis. Because the great majority of patients who are first seen with acute myocardial infarction have atherosclerotic coronary artery disease, there is usually little thought given to other causes, except in children where congenital coronary anomalies are considered. However, there are multiple other conditions, albeit far rarer than atherosclerosis, that can result in clinical acute myocardial infarction, and a classification of these other conditions, an anatomic-pathophysiologic one, was developed from illustrative material from the files of the Armed Forces Institute of Pathology. This classification is an inclusive listing of all conditions, however unusual, that can result in acute myocardial infarction.

Acute Disease↗
PubMed1975

Correlation of "critical" left coronary artery lesions with positive submaximal exercise tests in patients with chest pain.

This study correlates the anatomic pathologic coronary anatomy found by arteriography in each of three groups of symptomatic patients, all with coronary artery disease, divided according to the magnitude of ST-segment depression after an adequate submaximal treadmill exercise test. Group I consists of 45 patients with ST-segement depression of 2 mm. or more, Group II of 31 patients with ST-segment depression between 1.0 and 1.9 mm., and Group III, 30 patients with 0 to 0.9 mm. ST-segment depression. Seventy-five per cent of the patients in Group I had critical lesions defined as (1) 75 per cent or greater narrowing of left main coronary artery (LMCA), (2) 75 per cent or greater obstructive left anterior descending and left circumflex coronary artery both proximal to any major branching, the so-called left main equivalent (LME) lesions, and (3) 90 per cent or more obstruction of the left anterior descending coronary proximal to any major branches. Of patients in Group I, 24 PER CENT Had LMCA lesions, 29 per cent had LAD lesions. Eight-two per cent of Group I patients had two- or three-vessel disease. All patients with LMCA lesions had 2 mm. or more ST-segment depression. Over 95 per cent of patients with "critical" lesions is less than 5 per cent in the presence of an adequate aubmaximal treadmill test that shows less than 1 mm. of ST-segment depression, it is concluded that in such patients with medically controllable angina, coronary arteriography is not necessary.

Adult↗
PubMed1975

Spontaneous graft closure in anomalous origin of the left coronary artery.

Several reports of successful correction of anomalous origin of the left coronary artery from the pulmonary artery utilizing a graft to the ascending aorta have demonstrated the feasibility of this procedure. The patient described in this report developed proved delayed occlusion of the saphenous vein graft with a fatal outcome. This was a result of intimal fibrous hyperplasia identical to that seen in adults following the placement of the saphenous vein bypass graft for treatment of atherosclerotic coronary disease.

Child↗
PubMed1975

Absence of echocardiographic abnormalities of the anterior mitral valve leaflet in rheumatoid arthritis.

Thirty-five consecutives patients with classic or definite rheumatoid arthritis underwent echocardiography to evaluate the motion of the anterior mitral valve leaflet. Adequate echocardiograms were obtained in 31 patients. All 31 patients showed normal valve motion and a normal EF slope. If meticulous technique was not observed, a falsely low value for the EF slope was obtained and a normal slope was found when the method was improved. This study shows that echocardiographic abnormalities of the anterior mitral valve leaflet rarely, if ever, occur in patients with rheumatoid arthritis, provided that careful attention to recording method is observed.

Adolescent↗