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Biomedical subjects

M Cullen

Publications and source records attributed to M Cullen.

At least 73 records · Page 4Linked to original sources

Antenatal diagnosis of renal anomalies with ultrasound. I. Obstructive uropathy.

During a 5-year period, a diagnosis of obstructive uropathy was made in 25 fetuses. Eight of them had unilateral obstruction and 17 were affected bilaterally. The most common condition encountered was urethral obstruction by posterior valves. The site and nature of the obstruction were correctly identified in 22 of the 25 fetuses. Among the 17 who had bilateral obstruction, only three survived. In contrast, only one infant with unilateral obstruction died (of unrelated causes). Oligohydramnios in low-level (urethral) obstruction was a uniformly lethal finding. Relief of urethral obstruction in two fetuses after 20 weeks of gestation did not result in survival of the infant, whereas shunting prior to 20 weeks in one fetus seemed to have a beneficial effect. On the basis of this experience, we suggest that unilateral obstruction would be treated best by conservative management, while in bilateral obstruction invasive treatment may be effective if initiated early in gestation, before significant oligohydramnios occurs.

Female↗

Computing to control the drug bill.

The Derbyshire pharmaceutical computer system has been developed in collaboration with UniChem to give better stock control and thus make savings in the total drug bill. It is described by Mike Cullen, area pharmaceutical officer, and David Thomas, finance officer, South Derbyshire HD.

Centralized Hospital Services↗

American Burn Association/Shriners Hospitals for Children burn outcomes questionnaire: construction and psychometric properties.

To develop a standardized, practical, self-administered questionnaire to monitor pediatric patients with burns and to evaluate the effectiveness of comprehensive pediatric burn management treatments, a group of experts generated a set of items to measure relevant burn outcomes. Children between the ages of 5 and 18 years were assessed in a cross-sectional study. Both parent and adolescent responses were obtained from children 11 to 18 years old. The internal reliability of final scales ranged from 0.82 to 0.93 among parents and from 0.75 to 0.92 among adolescents. Mean differences between parent and adolescent were small; the greatest difference occurred in the appearance subscale. Parental scales showed evidence of validity and potential for sensitivity to change. In an effort to support the construct validity of the new scales, they were compared with the Child Health Questionnaire and related to each other in clinically sensible ways. These burn outcomes scales reliably and validly assess function in patients with burns, and the scales have been developed in such a way that they are likely to be sensitive to change over time.

Activities of Daily Living↗

Walking the talk: how effective boards accelerate performance. Interview by Elizabeth Preiss, Ron Shulman, and Patrick O'Callaghan.

The interviews demonstrated the belief that boards are accountable for ensuring the effective performance of their organizations. A board's obligation and authority is not limited to recruiting, appointing and replacing the organization's CEO and officers. It must also guide, shape, improve and reward what people do on the job. Performance management is not a simple process. It depends on a number of contributing factors operating in concert. To perform well, people must understand what is expected of them, their work context and their role. They must receive appropriate feedback on how they are doing from someone whom they respect and trust, someone with insight into their jobs and authority to manage them. The board's ability and obligation to contribute leadership, to be the primary force steering the organization, rests on the effectiveness with which it is able to play the performance management role.

Canada↗