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M Crozier

Publications and source records attributed to M Crozier.

7 recordsLinked to original sources
PubMed2000

French experience of quality assessment of quantitative urinary analysis.

Since 1986, clinical biochemists from the Rhône alpes area, in collaboration with a non-profit-making association (Pro Bio Qual), have been conducting an inter-laboratory quality assurance program for quantitative urine analysis. We investigated the precision and accuracy of individual methods and measurement systems routinely used in the monthly control for 13 analytes: albumin, alpha-amylase, calcium, chloride, creatinine, glucose, magnesium, phosphorus, potassium, total protein, sodium, urea, and urate. The number of laboratories participating in the program increased from 60 in 1986 to 277 in 1999. In 1986, the greatest inter-laboratory imprecision occurred in the assay of urinary total protein, because the commonly used sulfosalicylic acid turbidimetric methods displayed poor precision. Since 1989, the increasing use of pyrogallol red or Coomasie Blue dye colorimetric methods has improved inter-laboratory precision markedly. The acceptable precision and good practicability have encouraged the general use of the pyrogallol red method. As for albumin analysis, which uses a specific immunologic method, the precision was reasonably good. Quality assessment of chloride and sodium decreased when the method performance improved for other analytes (calcium, creatinine, glucose, magnesium, phosphorus, potassium, urea, urate). This program has helped the laboratories to improve the quality of quantitative urine analysis, particularly for total protein.

France↗
PubMed1995

Pelvic exenteration for adenocarcinoma of the uterine cervix.

The objective of this study was to describe and compare the outcome of patients with recurrent adenocarcinoma versus squamous cell carcinoma of the uterine cervix who have been treated with pelvic exenteration. All patients undergoing pelvic exenteration for cervical adenocarcinoma from 1955 to 1989 were identified and a retrospective review was conducted. For these 35 patients, we identified 70 controls who had exenteration for squamous cell carcinoma and who were matched for node status, year of procedure, and type of procedure. No significant difference was noted between the control group and the adenocarcinoma group for size of recurrent tumor, status of margins, presence of hydronephrosis prior to exenteration, and the time elapsed from initial diagnosis to exenteration. The two groups were compared for survival and recurrence pattern. Median patient age was 47 years (range 22-70). All patients had prior pelvic radiotherapy. Thirty patients had total pelvic exenteration and 5 had anterior exenteration. There were 3 postoperative deaths (8.6%). Median survival was 38 months for the adenocarcinoma patients and 25 months for the squamous patients (P > 0.99). The overall survival between the two sets of patients was very similar (log rank P = 0.86). There were 23 postexenteration recurrences among the adenocarcinomas (22 in which the site is known) and 32 postexenteration recurrences among the squamous patients (30 with known site). For the adenocarcinoma patients, 14 of 22 had a distant recurrence versus 14 of 30 for the squamous patients (P = 0.27). Patients with central recurrence of cervical adenocarcinoma can be successfully treated with pelvic exenteration and have survival rates similar to squamous carcinoma.

Adenocarcinoma↗
PubMed1990

Pet turtles: a continuing international threat to public health.

The occurrence of Salmonella spp. in red-eared (Pseudemys scripta elegans) turtle eggs imported into Canada from Louisiana in June to September 1988 was examined. Of 28 lots tested, six (21%) lots from three of four exporters harbored salmonellae. Salmonella poona and Salmonella arizonae were frequently encountered in both fertile eggs and packaging moss. Turtles hatched in our laboratory from affected lots of eggs shed Salmonella in tank water for up to 11 months. Widespread use of gentamicin on turtle farms to produce Salmonella-free eggs for export apparently encouraged development of antibiotic resistance in bacterial strains. Of 37 Salmonella strains isolated in this study, 30 (81%) were gentamicin resistant. Such high levels of antibiotic-resistant salmonellae in turtle eggs pose a serious human health risk. Further marketing of turtle eggs and hatchlings should be curtailed until consistent production and distribution of Salmonella-free stocks can be assured.

Animals↗
PubMedDate not supplied

The boundaries of business: commentaries from the experts.

The World Leadership Survey, which began a worldwide dialogue on a set of important issues facing managers in the 1990s, continues with commentaries from four recognized experts, each of whom addresses the survey results from a different perspective. Kenichi Ohmae, chairman of McKinsey and Company in Tokyo, addresses "The Perils of Protectionism." Ohmae argues that the old definitions of national boundaries and corporate interests reflect obsolete economic theories. The real test of national well-being, Ohmae suggests, should be the economic welfare of a nation's citizens. Sylvia Ann Hewlett, economist and former director of the Economic Policy Council in New York, analyzes the survey in terms of "The Human Resource Deficit." According to Hewlett, four principles should guide corporate strategies in the 1990s: human resource development should move up the scale of corporate priorities; a family-friendly workplace will attract and keep talented workers; companies will take limited direct responsibility for training and education; the private sector will promote public investment in social issues. James E. Austin, the Richard P. Chapman Professor of Business at the Harvard Business School, writes about "The Developing-Country Difference." In developing countries, Austin observes, managers display attitudes and follow practices that diverge from those in developed nations. In particular, the role of government, investments in education and technology, and environmental concerns set these nations apart. Michel Crozier, president of the Centre de Sociologie des Organisations in Paris, writes about "The Changing Organization." In the 1990s, Crozier argues, managers need to break from old management theories and practice, questioning hierarchy, control, distance, access to information-the whole managerial system.

Administrative Personnel↗