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Biomedical subjects

M Crane

Publications and source records attributed to M Crane.

At least 109 records · Page 6Linked to original sources
PubMed1998

The healed diabetic foot. What next?

Reulceration of the healed diabetic foot must be prevented to end the cycle of degradation that leads to amputation in so many of these patients. Education, identification of risk factors, therapeutic shoe gear, prophylactic surgery, judicious physical examination, and follow-up by a multidisciplinary team can break this cycle. "Those who suffer losses due to diabetes are not just statistics on a chart. They are people whose talents and wisdom are needed and whose problems deserve our unified efforts. Together we can make life more just and more joyful for generations to come".

Diabetic Foot↗
PubMed1998

Gender and history of suicidality: are these factors related to U.S. college students' current suicidal thoughts, feelings, and actions?

Gender and history of suicidality (HS vs. NoHS) were related to current symptoms of depression, reasons for living, and reports of self-destructive and life-threatening behavior in a college student sample. Overall, college men reported engaging in more life-threatening and potentially suicidal behavior than college women on the Life Attitudes Schedule (LAS). No gender effects were obtained on the symptoms of depression and reasons for living measures. Results suggest that the LAS may be a particularly effective way to identify college students at risk for self-destructive and suicidal behavior. As expected, HS individuals were more depressed, had fewer reasons for living, and reported engaging in more current suicidal and life-threatening behavior than NoHS participants. However, gender and history of suicidality were found to interact. NoHS women reported avoiding a variety of injury-producing and health-diminishing behaviors that were common for all other groups of college students. Meanwhile, HS women endorsed fewer current reasons for living than did NoHS women, NoHS men, and NoHS men. These findings were interpreted both with regard to cultural and gender-specific expectations for the expression of self-destructive, suicidal, and life-threatening behavior. Implications for the prevention of college women's and men's suicidal behavior were also noted.

Adult↗
PubMed1997

Getting peanuts.

Explore the source record for details and available documents.

Data Collection↗
PubMed1997

The accuracy of frozen section by tumor weight for ovarian epithelial neoplasms.

This study evaluated the effect ovarian weight has on the accuracy of frozen sections in serous and mucinous ovarian tumors. The study group included 294 patients who had an initial frozen section (189 serous and 105 mucinous tumors) at surgery. The pathology reports were separated into subgroups (benign, borderline, or malignant). Tumors were broken down into three weight categories: < or = 450 g, > 450 to < or = 1360 g, and > 1360 g. In each weight category, accuracy, sensitivity, specificity, and positive and negative predicative values were calculated on frozen sections. The mean weight of the ovarian tumors was 1042 g. As the weight increased in serous tumors, the sensitivity fell from 96.2 to 93.8 to 75%, respectively, in each weight category. The same trend was noted with mucinous tumors as sensitivity fell from 91.7 to 87.5 to 66.7%, respectively. With an increase in the size of ovarian tumors, a decrease in the sensitivity of frozen section was observed. With tumors greater than 1360 g, sensitivity was only 69%. Twenty-three percent of ovarian tumors revealing borderline diagnosis at frozen section were malignant on the final pathology report, with the greatest misclassification in > 1360-g mucinous tumors (50%). For patients with large ovarian tumors, consideration should be given to performing staging at the time of the initial laparotomy.

Epithelium↗
PubMed1996

Zidovudine use to reduce perinatal HIV type 1 transmission in an urban medical center.

OBJECTIVE: To evaluate whether zidovudine treatment was accepted and used by pregnant women subsequent to the release of the results of a multicenter, randomized, placebo-controlled trial (AIDS Clinical Trial Group [ACTG] Protocol 076) that showed that zidovudine significantly reduced maternal-infant human immunodeficiency virus (HIV) type 1 transmission. DESIGN: Prospective study. SETTING: A community hospital with an integrated, multidisciplinary HIV-dedicated program located in an impoverished, HIV-endemic urban setting. PARTICIPANTS: All HIV-infected pregnant women identified after the release of the ACTG 076 results who were offered zidovudine therapy to reduce maternal-infant transmission. RESULTS: Only 49 of the 125 HIV-infected pregnant women delivering at our site during this study period were identified prenatally. Perinatal zidovudine therapy was chosen by 37 (75%) of 49 women. Women refusing zidovudine were more likely to report injection drug use as their HIV risk factor and to continue to use drugs during their pregnancy. Of women choosing zidovudine and delivering, 24 of 36 received all components of their elected therapy. The intrapartum dose was missed by 12 women, 4 of whom also missed their prescribed prenatal oral therapy. Lack of adherence to chosen therapy was associated with continued cocaine use during pregnancy. CONCLUSIONS: Zidovudine therapy to interrupt vertical transmission of HIV was not widely used by these HIV-infected pregnant women. Further studies evaluating factors affecting the acceptance and use of recently published public health recommendations are needed.

Adolescent↗