Biomedical subjects

M Corsi-Cabrera

Publications and source records attributed to M Corsi-Cabrera.

At least 37 records · Page 2Linked to original sources

PubMed1997

Effect of spatial ability and sex on inter- and intrahemispheric correlation of EEG activity.

Inter- and intrahemispheric correlation of the EEG activity at rest was computed in two groups of men and women, between 17 and 21 years old, with extreme degrees of spatial ability (SA) evaluated by the Spatial Relations Subtest of the Differential Aptitudes Test (DAT). Interhemispheric (INTERr) and intrahemispheric (INTRAr) EEG correlations were computed by means of Pearson product-moment coefficients for 5 EEG bands after digitally filtering with an FFT. Women showed significantly higher INTERr of alpha 1 between left and right centrals, lower INTRAr between right frontal and right central regions and lower INTRAr within the left than in the right hemisphere. High SA subjects showed lower INTERr between left and right frontal derivations and higher INTRAr between frontal and parietal and between central and parietal regions of both hemispheres. Sex interacted with SA in INTRAr of alpha between right frontal and right temporal regions with high SA women showing lower INTRAr than low SA women and than men. The present results indicate a different inter- and intrahemispheric functional organization in men and women and in subjects with high and low spatial ability.

Adolescent↗

PubMed1997

Sex differences in EEG in adult gonadectomized rats before and after hormonal treatment.

EEG activity was recorded from the left and right parietal cortex in adult male and female Wistar rats that were gonadectomized (GNX) after puberty during 2 days without and 3 days with hormonal treatment (either testosterone propionate, 5 alpha-DHT or vehicle in males and progesterone, estradiol benzoate or vehicle in females). In contrast to EEG characteristics reported for intact rats, GNX abolished right over left parietal activation in both sexes and, sex differences in EEG interhemispheric correlation and in theta and delta relative power in the right parietal; additionally GNX males showed higher absolute power than females. Hormonal treatment reestablished interparietal asymmetry in both sexes and a lack of sex differences in absolute power, however, it was not enough to reestablish sex differences in delta and theta proportion in the right parietal nor in interhemispheric correlation. Differential effects were obtained with testosterone propionate and 5 alpha-DHT in males suggesting that activational effects of testosterone on EEG are probably exerted through testosterone or its aromatized metabolites. The results of our study indicate that the activational effects of gonadal steroids after puberty are necessary for maintaining sex differences in the EEG of the adult rat.

Animals↗

PubMed1996

Inter and intrahemispheric EEG correlation as a function of sleep cycles.

1. Inter (INTERr) and intrahemispheric (INTRAr) EEG correlation were assessed in 8 young male adults during wakefulness (W) with eyes closed before going to sleep, and during stage 2 (S2), stage 4 (S4) and paradoxical sleep (PS) of the first three sleep cycles during the second night spent at the laboratory. 2. Pearson product-moment correlation were calculated between EEG signals of each pair of electrodes (C3, C4, F3, F4, T3, T4) for every 0.5 Hz from 1.5 to 15 Hz. 3. INTERr and INTRAr of 1.5-6.5 and 11-15 Hz were significantly higher during stage 2 and 4; INTERr of 1.5-6.5 Hz was also higher during PS in cycle 1 and 2, whereas INTERr and INTRAr of 7-10.5 Hz were lower than during wakefulness. 4. INTRAr of S2 and S4 approximated, whereas INTRAr oF PS moved away from W over successive sleep cycles. 5. These data show that cortical changes during sleep are also observed in functional differentiation between cortical sites. Inter and intrahemispheric differentiation is attenuated during stage 2 and 4 while during PS only interhemispheric differentiation is attenuated but intrahemispheric differentiation is accentuated compared to wakefulness. This pattern of cortical differentiation may be of relevance for the understanding of mental activity changes during sleep.

Adult↗

PubMed1996

EEG coherence or EEG correlation?

In view of the widespread use of electroencephalographic correlation (r) and coherence (Coh) analyses in studying brain functional relationships, it seems important to illustrate results yielded by both methods. Although they are considered as equivalent, they show important differences. Results obtained from r and Coh were compared using: (a) 2 Hz sinusoidal signals, where phase and amplitude were artificially manipulated and, (b) Coh and r spectra obtained between each pair of derivations (C3, C4, F3, F4, T3 and T4) from wakefulness, stage 2, stage 4 and paradoxical sleep (n = 8). The following results were obtained: significant Pearson product-moment coefficients were obtained between r and Coh spectra in the range of 0.86 to 0.96 for interhemispheric and 0.60 to 0.90, for intrahemispheric paris; as a result of principal component analyses, the same three frequency bands were formed for r and Coh spectra with the exception of one single bin; similar results for r and Coh were obtained by two-way ANOVAs (physiological stages by derivations). In conclusion, as expected, a high degree of comparability between r and Coh was observed under normal physiological conditions and with the use of good quality recordings.

Algorithms↗

PubMed1996

Time course of reaction time and EEG while performing a vigilance task during total sleep deprivation.

Nine young adult male (23-30 years old) paid volunteers were subjected to total sleep deprivation (TSD), after two consecutive nights in the laboratory, for 40 hours (from 0800 hours on the first day to 2400 hours on the following day). Oral temperature (OT), reaction time (RT) in a visual vigilance task, and electroencephalogram (EEG; C3, C4, T3, and T4) while performing the task were recorded every 2 hours during TSD and after recovery sleep. One second of EEG, before target and non-target stimuli for every subject and condition was visually inspected, and artifact-free epochs were Fourier transformed. Absolute power (AP) was calculated for 4-20 Hz (full band) and for theta, alpha 1, alpha 2, and beta 1. Analyses of variance (ANOVAs), with TSD and time-of-day as factors, showed the following significant results. TSD induced an increase in RT and AP of the full band at C3 and C4, of all bands at C3, of theta at T3, and of beta 1 at T4 (p < 0.009 for all comparisons). No time-of-day effects nor interactions were found. OT was not affected by TSD. All variables returned to baseline values after recovery sleep. RT and EEG power showed a linear increase with accumulating hours of wakefulness. The increment in RT also correlated with the increase in EEG power. The results demonstrate that the increment in RT is associated with the increase in AP, particularly in the left central cortex; that the EEG may be used to identify sleepiness; and that EEG during task performance is more sensitive to TSD than during relaxed wakefulness.

Adult↗

PubMed1995

Effects of prenatal testosterone treatment on sex differences in the EEG activity of the rat.

Pregnant rats were injected either with 2 mg of testosterone propionate or with vehicle on days 14 to 19 of gestation. Ano-genital distance (AGD) and body weight (b.wt.) of the offspring were measured at 10, 20, 30, 45, 60, 75 and 90 days of age. Between 98 and 104 days of age the EEG activity was monopollarly recorded with electrodes implanted in the left and right parietal cortex. Males showed higher interhemispheric correlation than females in delta, theta, alpha] and the total band. Delta relative power (RP) was lower and theta RP was higher in males than in females. These sex differences were eliminated with the prenatal testosterone treatment (PTT), which exerted a masculinizing effect on females. Absolute power (AP) did not show sex differences, but PTT produced an increase in the AP of all bands, except for beta2, regardless of sex. PTT increased the AGD at all ages, except 90 days. This increase was significant only in females at 10, 30, 45, 60 and 75 days of age. PTT increased the b.wt. at all ages, regardless of sex. These data indicate that the organizational action of sex hormones during the prenatal period plays an important role in the establishment of EEG sex differences in the rat.

Aging↗

PubMed1995

Effect of spatial ability and sex on EEG power in high school students.

Performance at eight cognitive tests and EEG spectral power at rest was computed in 2 groups of men and women, between 17 and 21 years of age, with extreme degrees of spatial ability (SA) evaluated by the spatial relations subtest of the DAT: a low spatial ability group (10 men, 10 women) with scores below percentile 30 and a high spatial ability group (10 men, 10 women) with scores above percentile 80. Ten EEG artifact free samples, 4.096 sec each, were analyzed and absolute (AP) and relative power (RP) were obtained for 5 frequency bands using an FFT. EEG was submitted to principal component analysis and two way ANOVAs. High SA showed lower AP in the entire spectrum with eyes open and closed, and lower alpha 1 RP with eyes open than low SA group regardless of sex. The difference between low and high SA was better explained by high alpha AP at all derivations and high theta AP at right derivations and at left central and occipital regions. Women showed higher beta 1 and beta 2 AP at all derivations except at temporal regions than men regardless of SA scores.

Adolescent↗

PubMed1995

Sex differences in interhemispheric correlation and spectral power of EEG activity.

EEG activity was recorded from left and right parietal cortex in adult male and female rats on a daily basis during 3 days. Absolute and relative power and interhemispheric correlation of the EEG activity were calculated and compared between males and females. Interhemispheric correlation of the theta rhythm was higher in males than in females. Interhemispheric asymmetry in absolute power was larger in males, who showed higher power in the right than in the left parietal for all bands except for delta. Beta2 relative power was significantly higher in females. These results indicate greater functional asymmetry and higher interhemispheric coupling of the parietal cortex in male than in female rats as assessed by cortical EEG activity.

Analysis of Variance↗

PubMed1995

Inter- and intrahemispheric EEG correlation during sleep and wakefulness.

Inter- (INTERr) and intrahemispheric (INTRAr) electroencephalographic (EEG) correlations were assessed in eight young male adults during wakefulness with eyes closed before going to sleep, and during stage 2, stage 4 and paradoxical sleep (PS) on the second night spent at the laboratory. Pearson product-moment correlations were calculated between EEG signals of every pair of electrodes (C3, C4, F3, F4, T3, T4) for six bands and for every 0.5 Hz from 1.5 to 15 Hz. Previous results of higher INTERr during sleep compared to during wakefulness were confirmed for the delta and theta bands during stage 2 sleep and PS and for sleep spindles during stage 2 sleep. The present results extend these findings to INTERr between F3 and F4 and during stage 4 sleep. INTRAr of 1.5-6.5 and 11-15 Hz was significantly higher during stages 2 and 4, whereas during PS INTRAr did not change. These data show that cortical changes during sleep are also observed in functional differentiation between cortical sites. Inter- and intrahemispheric differentiation is attenuated during stage 2 and 4 sleep, whereas during PS only inter-hemispheric differentiation is attenuated but intrahemispheric differentiation maintains similar levels of wakefulness. The attenuation of cortical differentiation may be of relevance for the understanding of mental activity changes during sleep.

Adult↗

PubMed1995

EEG interhemispheric correlation after callosotomy: one case study.

High interhemispheric EEG correlation (INTERr) or coherence has been interpreted as a consequence of callosal interconnections. The EEG of a callosotomized (two anterior thirds) 32-yr.-old patient was recorded during relaxed wakefulness with eyes closed. 100 2-sec. artifact-free epochs were digitally filtered into traditional broad bands and INTERr was calculated by means of Pearson product-moment coefficients. INTERr between anterior regions, where they should be expected, showed very few differences between data of this patient and those of two control groups of healthy persons. Only a few differences were observed between posterior regions where the callosum was intact. These results suggest that the role of the callosum is not crucial for INTERr and that subcortical influences and functional differentiation between hemispheres may be more plausible explanations for INTERr.

Adult↗

PubMed1995

Effect of total sleep deprivation on reaction time and waking EEG activity in man.

Nine paid volunteers were sleep deprived over a period of 40 hours. Every 2 hours during total sleep deprivation (TSD) and after recovery sleep, oral temperature (OT), reaction time (RT) in a vigilance task and electroencephalogram (EEG) with eyes open and closed (C3, C4, T3 and T4) were recorded. Ten artifact-free samples from each condition were Fourier transformed. Absolute power was calculated for six bands. Analyses of variance with deprivation and time of day as factors showed the following significant results: 1) TSD induced an increase in RT, of theta power in all derivations, of beta power in both centrals and a decrease of alpha power with eyes closed; OT was not affected. 2) All bands showed a peak of power at 1800 hours, 2 hours in advance of the OT acrophase at 2000 hours. All variables recovered baseline values after 1 night of sleep. Significant linear correlations of hours of wakefulness with EEG and RT, and of EEG power with OT and RT, were observed. The present findings show a linear increase in EEG power and RT with TSD, and a diurnal oscillation of EEG power, which is independent of TSD.

Adult↗

PubMed1994

Effects of paradoxical sleep deprivation and stress on the waking EEG of the rat.

Effects of 72 h of paradoxical sleep deprivation (PSD) and stress on the waking EEG of rats were studied using the water tank technique. EEG was recorded at left and right parietal cortex and the spectrum was analyzed before PSD, after 24, 48, and 72 h of PSD, and 24 h after recovery. Absolute and relative power and interparietal correlation were obtained. The same analyses were performed on a larger platform group and on a cold water-stressed group. The following significant changes were observed on the waking EEG: PSD produced a decrease in interparietal correlation, an increase in absolute and relative power between 7.3 and 9.3 Hz, and a decrease in the delta band relative power. The PSD effect on relative power was less specific on absolute power; relative power between 7.3 and 9.3 Hz was also increased in the large platform control group. Interparietal correlation was also decreased in both control groups but in the water-stressed animals it followed a different time course. The present findings suggest that PSD may affect brain function by increasing the level of hippocampal arousal, whereas the combination of stress and PSD affects interhemispheric coupling.

Animals↗

PubMed1994

Waking electroencephalogram activity as a consequence of sleep and total sleep deprivation in the rat.

Effects of 6 hours of total sleep deprivation (TSD) by gentle handling and 6 hours of sleep on the waking electroencephalogram (EEG) activity of 14 Wistar rats were studied during the lights-on portion of the light-dark cycle under two TSD schedules: a) TSD 0800-1400 hours and sleep 1400-2000 hours, and b) sleep 0800-1400 hours and TSD 1400-2000 hours. EEG was recorded monopolarly from left and right parietals referred to ipsilateral reference electrodes. Spectral analysis was performed on samples of waking EEG during TSD (each 30 minutes) and during sleep (each 60 minutes after enforced awakening). The following significant changes were observed: TSD induced a linear increase in the absolute power of delta (1.46-3.42 Hz) and the full band (1.6-24.9 Hz) and produced a decrease in the interparietal correlation of theta. Sleep induced the opposite results. Theta relative power (power in a band expressed as a percentage of total power between 1.46 and 24.9 Hz) showed a circadian effect. It was higher at 1400 hours than at 0800 and 2000 hours after both sleep and TSD conditions. Six hours of TSD were enough to induce significant changes in the waking EEG regardless of position of TSD in the lights-on period of the light-dark cycle.

Animals↗

PubMed1994

EEG oscillations during menstrual cycle.

12 sessions of EEG activity, one every second day, were recorded at F3, F4, C3, C4, P3, P4, O1 and O2 in 9 women with regular menstrual cycles. The following significant oscillations were observed: 1) absolute power was lower during periovulatory period; 2) absolute power of delta theta and alpha 1 was higher during premenstrual period whereas absolute power of alpha 2, beta 1 and beta 2 was higher during menstruation; 3) relative power of low alpha frequencies was lower and that of high frequencies was higher during premenstrual period; 4) interhemispheric correlation between frontals was higher during ovulation and between occipitals was higher during premenstrual phase; 5) no significant power asymmetries were observed. The present findings suggest higher activation of centro-parietal regions during menstruation and lower activation of frontal regions during premenstrual phase.

Adult↗

PubMed1993

Gender differences in the EEG during cognitive activity.

EEG activity of 16 adult volunteers. 8 male and 8 females was monopolarly recorded at P3 and P4 at rest and during solution of three series of tasks: one analytic, one spatial and one mixed demanding both kinds of processing. The following main effects were observed: Men showed significantly higher beta relative power than women, while women showed significantly higher alpha relative power than men during all conditions. Alpha relative power decreased, while theta relative power increased during tasks solution in both sexes. Beta relative power was significantly higher at the left parietal only in men. Interparietal correlation was significantly higher in women than in men during all conditions and bands. For the theta band it increased from baseline values during tasks solution in men, while in women it decreased during the analytic task.

Adolescent↗

PubMed1992

EEG activity during estral cycle in the rat.

EEG activity was recorded from right and left parietal cortex in adult female rats daily during 6 days. Immediately after EEG recording vaginal smears were taken and were microscopically analyzed to determine the estral stage. Absolute and relative powers and interhemispheric correlation of EEG activity were calculated and compared between estral stages. Interhemispheric correlation was significantly lower during diestrous as compared to proestrous and estrous. Absolute and relative powers did not show significant differences between estral stages. Absolute powers of alpha1, alpha2, beta1 and beta2 bands were significantly higher at the right parietal cortex. Comparisons of the same EEG records with estral stages randomly grouped showed no significant differences for any of the EEG parameters. EEG activity is a sensitive tool to study functional changes related to the estral cycle.

Animals↗

PubMed1992

Changes in the waking EEG as a consequence of sleep and sleep deprivation.

Electroencephalographic (EEG) activity was monopolarly recorded during resting wakefulness in 10 volunteers under the following conditions: at night before going to sleep, at night before total sleep deprivation, in the morning after waking, in the morning after sleep deprivation and at night after having slept during the day. Absolute and relative power and inter- and intrahemispheric correlation were established. After diurnal and nocturnal sleep as compared to sleep deprivation, we obtained the following significant results: interhemispheric correlations were higher; intrahemispheric correlations were lower; absolute power of alpha 2, beta 1 and beta 2 was lower; and relative power of alpha 2 and beta 2 was lower. EEG changes as a consequence of sleep or lack of sleep are dependent on prior sleep and/or wakefulness and not on circadian phase. EEG activity during wakefulness is a sensitive parameter and a useful tool to assess the consequences of sleep on brain functional organization.

Adult↗

PubMed1991

Spatial ability in classic dancers and their perceptual style.

The relation between spatial ability (body orientation and body awareness) and field dependence/independence was assessed by measuring performance on the Embedded Figures Test and WISC or WAIS Block Design at four different training levels in classical ballet, beginners to advanced, and a control group with no training in ballet, gymnastics, or sports (n = 70). No significant correlation was found between perceptual style or Block Design performance and body orientation or body awareness at any of the four levels of training. No significant differences were observed between the advanced group and the control group. Training in a particular type of spatial skill such as orientation within surrounding space was not related to the skill required to manipulate an abstractly represented space.

Adolescent↗