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Biomedical subjects

M Coppola

Publications and source records attributed to M Coppola.

94 records · Page 6Linked to original sources
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[Primary hyperaldosteronism caused by monolateral adrenal hyperplasia].

We have reported two patients with unilateral adrenal hyperplasia as a rare cause of primary aldosteronism, and discussed the literature on this subject. When diagnosed by NMR-CT imaging and selective sampling from adrenal veins, the treatment of this disorder appears to be surgical. Whether its pathogenesis is related to the more common varieties of primary aldosteronism is open to speculation according to metabolic findings.

Adrenal Glands↗
PubMedDate not supplied

[Cystic dilatation of the seminal vesicles: which diagnostic approach?].

PURPOSE: We investigated the frequency, clinical features, diagnostic course and therapy of congenital and acquired seminal vesicle cysts. MATERIAL AND METHODS: Seven vesicular cysts were found in adult subjects in 1995-1996. All diagnoses were made with suprapubic and transrectal US, CT and MRI. Vesiculo-deferentography was never used for diagnosis. Patient age and symptoms, cyst site, structure and dysembryogenetic associations were considered for diagnosis. RESULTS: All the patients were adult and all but one fertile. Age ranges were IV (43%), III and V (28.5%) decades. The cyst was congenital in 5 patients, associated with other dysplasias in 60% of them, and acquired in 2 patients. 57% of patients had urogenital symptoms and 2 patients (28.5%) had no clinical signs. US was performed for fertility tests in one patient. The left gland was always and exclusively involved; its size ranged 3.2 to 5.8 cm and its shape was characteristic only in 2 acquired cysts. DISCUSSION: Both abdominal and rectal US examinations were always performed and always reliably showed cyst site, origin, size and components. CT confirmed local findings and was also used to study the abdomen assessing renal presence and function. MRI permitted the best anatomical study with the multiplanar demonstration of the relationships between small pelvis structures. CONCLUSIONS: Congenital cysts and acquired distension of the seminal vesicles are uncommon findings also because they are difficult to diagnose. Diagnostic imaging reliably differentiates vesicular cysts from other cystic collections in that region, providing enough information to distinguish acquired from congenital forms, the former curable with drug treatment and the latter requiring more invasive therapy. Relative to site prevalence (100% in the left gland), we do not know if this was an aleatory finding or it indicated an actual congenital predisposition. US yields the indispensable diagnostic findings, but MRI should be always performed to ensure diagnosis, to study the abdomen and to plan possible surgery.

Adult↗