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Biomedical subjects

M Conte

Publications and source records attributed to M Conte.

At least 37 records · Page 2Linked to original sources

Ovarian carcinoma: an ultrasound study.

Between March 1986 and March 1989, 65 epithelial ovarian carcinomas were studied by means of real time high resolution ultrasound. The sonographic findings were correlated with FIGO stage, histotype and histological grade. The echostructure was compared with that of a group of 141 benign controls. Moreover, some sonographic patterns, significantly more frequent in the malignant tumors (ascites, irregular borders, peritoneal growths), were identified. The diagnosis of malignancy was as accurate as 90.0%, sensitivity and specificity were 84.7% and 92.3% respectively. Our results, coupled with the low costs involved and the non-invasiveness of the method, thus confirm that ultrasound can still be considered a primary technique in the preoperative assessment of ovarian masses.

Adenocarcinoma

Pelvic lymphocele following radical para-aortic and pelvic lymphadenectomy for cervical carcinoma: incidence rate and percutaneous management.

Thirty-six women, treated with radical hysterectomy (Piver types III-IV) plus systematic para-aortic and pelvic lymphadenectomy for cervical carcinoma, underwent serial postoperative ultrasound examinations to determine the incidence of lymphocele and the therapeutic efficacy of percutaneous catheter drainage. Pelvic lymphoceles, ranging in volume from 46-300 mL, occurred in eight patients (22.2%) between the 12-24th postoperative day. Percutaneous catheter drainage, inserted under local anesthesia, was used for a mean time of 14.5 days (range 4-32), resulting in a mean daily drainage of 92.2 mL and a mean total volume of 1727.5 mL per patient. Catheter drainage allowed complete clinical and sonographic remission in all cases, and only one asymptomatic recurrence was observed at 3-month and 6-month follow-up. Ultrasound-guided percutaneous catheter drainage has proved to be a well-tolerated, safe, and effective technique in the management of lymphocele that obviates the need for more invasive surgical procedures.

Drainage

[Monotherapy, empirical and targetted, with imipenem-cilastatin in sepsis of bacterial origin].

The authors describe an open study in 22 patients with febrile conditions of unknown origin who were treated with imipenem-cilastatin while waiting for routine laboratory and culture tests. These were done immediately at the patients' entry into hospital, after which imipenem-cilastatin treatment was started immediately, and was subsequently confirmed by the isolates and culture tests. The drug was found to be active and to eradicate the responsible organism in all cases. In addition, it was found to be easy to handle and not to give rise to side-effects or changes in laboratory tests.

Adolescent

[Current therapeutic approach to adnexal cysts].

From a 5-year study of 481 ovarian tumors, the authors discuss their therapeutic management and try to answer two basic questions: what is the proportion of cystic tumors, that actually are carcinomas? To what extent the tapping of a cancerous "cyst" may cause the spreading of the tumor?

Biopsy, Needle

[Psychotropic drugs and pregnancy].

The multiplicity of psychotropic medications and their widespread prescription, justifies a review of the possible effect of psycholeptics and psycho-analeptics on the fetus in-utero, and on lactation. The authors attempt to differentiate between diverging if not conflicting opinions in most cases. They conclude that it is necessary to prescribe these products only with precise indications and after careful consideration.

Abnormalities, Drug-Induced

Induction of ovulation by intermittent intravenous purified follicle-stimulating hormone in polycystic ovarian disease.

IIV FSH was administered to eight women with PCOD to induce ovulation. These patients had been previously treated unsuccessfully with CC or IM gonadotropins. The drug was administered by a pump at 120-minute intervals. Dosage was 1 ampule Metrodin (75 IU of FSH less than 0.11 IU of LH)/day. Eight cycles of treatment were effected. With the IIV regimen, ovulation rate was 75% (six cycles). Two multiple pregnancies and one abortion (mola vescicularis) were observed. Preovulatory E2 plasma levels and the number of follicles recruited per cycle varied from 530 to 3800 pg/ml and from 4 to 15, respectively. Maximal follicular diameter was between 16 and 28 mm. LH levels significantly decreased, while FSH levels were unchanged, resulting in a decrease of LH/FSH ratio. It is concluded that the IIV FSH regimen offers an additional modality for the induction of ovulation in PCOD patients. Further clinical trials with alternative regimens are needed, however, to identify the optimal dosage and frequency of administration of the drug.

Adult

[Cutaneous metastases of a prostatic cancer. Apropos of a case].

Cutaneous metastasis from prostatic carcinoma are quite unusual (40 reported cases in the literature), usually occurring several months or years after initial diagnosis. In our patient tumoral nodules were exclusively located on the scrotum. Prostatic nature of metastatic cells were proved by Immunocytochemistry.

Adenocarcinoma