Search PubMed⌕ Search

Biomedical subjects

M Chousterman

Publications and source records attributed to M Chousterman.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Percutaneous endoscopic gastrostomy. Indications and follow-up in 30 patients].

The indications and results of percutaneous endoscopic gastrostomy (PEG) were reviewed in 30 consecutive patients, most of whom had problems of deglutition secondary to the treatment of ENT neoplasia. The procedure was successful in all patients but some difficulty was encountered in 4 cases. There were no major complications or fatalities. The benign complications were all amenable to medical therapy and did not require ablation of the gastric tube. In general, PGE was well tolerated and an easy to use method of nutritional assistance, allowing most patients to gain weight. In the authors' experience, this technique has an important role to play in the nutritional assistance of patients with problems of deglutition due to neurological disease or ENT neoplasia. The relative innocuity of PEG gives it a great advantage over surgical gastrostomy.

Adult↗
PubMed1988

[Percutaneous endoscopic gastrostomy. Indications and follow-up in 52 patients].

A nutritional support was indicated in 52 patients, most of whom had deglutition problems linked with post-therapeutic after-effects of neoplasia of the ORL sphere. Assistance was possible in all the cases, with difficulty in 9 cases. There were only three major complication (two of which necessitated the removal of the tube) and no fatalities. Benign, more numerous complications were all medically curable and did not necessitate the removal of the tube. The follow-up of the patients showed remarkable tolerance to, and nonproblematic use of, the GPE tube as a nutritional aid leading, in the majority of cases, to a weight gain, even when ambulatory. Our experience suggests that this technique deserves a prime place as a nutritional aid for cases of deglutition problems, of neurological origin, and in ORL cancers. Its relative safety must undoubtedly make it preferable to the surgical technique.

Adult↗
PubMed1984

[Comparison of bacteriological and immunoenzyme methods for the serum determination of sisomicin. Pharmacokinetic application in the human].

A modification of the serum gentamicin immunoenzymatic method (Syva- Biom erieux kit) for sisomicin assay is proposed and compared to the bacteriological reference method. It shows a higher sensitivity (0.1 mg.l-1) with a shortened time of analysis (less than 1 hour) and a good reproducibility (range: 4.7% to 1.6% for concentrations between 0.5 mg.l-1 and 10 mg.l-1) but the concentrations are 15 p. cent lower as compared to the bacteriological method. A pharmacokinetic study, performed in five patients, enables us to demonstrate the praticability of this method for the adaptation of the dosage regimen in renal insufficiency.

Biological Assay↗
PubMed1983

[Epidemiologic relations between arteriopathy of the lower extremities and chronic gastroduodenal ulcer].

The authors report the results of a study of 3 565 consecutive patients over 30 years of age, of French nationality living in the Paris region, hospitalised over a 5 year period in a Department of internal medicine and vascular pathology. The incidence of gastroduodenal ulcer was compared in each sex in 10 year age groups in 764 patients with arterial disease and 2 801 patients without arterial disease. The incidence of ulcers was higher in patients with occlusive arterial disease in men in the 50 to 59 year age group (20,4 p. 100 compared to 9 p. 100, p less than 0,01), and in the 60 to 69 year age group (20,3 p. 100 compared to 9,8 p. 100, p less than 0,001), and after 70 years of age in females (12,8 p. 100 compared to 4 p. 100, p less than 0,01). The overall incidence in all patients with arterial disease (16,7 p. 100 of all 591 males, and 12,1 p. 100 of all females) was higher than in a corresponding control group (9,7 p. 100, p less than 0,0001, and 4,8 p. 100, p less than 0,001 respectively). These results only concern chronic ulcers. There was no difference in the incidence of acute ulcers.

Adult↗
PubMed1983

Clinical value of the determination of an interferon-induced enzyme activity: studies of the 2'5' oligoadenylate synthetase activity in peripheral blood lymphocytes of patients.

The 2'5' oligoadenylate synthetase (2'5' A synthetase) is one of the interferon-induced enzymes. The measurement of its activity may thus reveal the presence of interferon, which is one of the body's non-specific antiviral, antitumor, and immunoregulatory agents. We found a constant level of this enzyme activity (mean value: 0.31 units +/- 0.13 S. D.) when measured in the white blood cells of healthy subjects (104). The majority of the patients with viral (27/30), bacterial (13/16) and autoimmune (15/16) diseases showed a 2'5' A synthetase activity greater than 0.57 units (mean value of the control + S. D.). Conversely the 2'5' A synthetase activity level was normal or low in malignancies and in diseases depending on other aetiologies than those described above. Therefore this simple an rapid biochemical assay seems to be useful for clinical study of infectious and inflammatory diseases.

2',5'-Oligoadenylate Synthetase↗
PubMed1981

[Constrictive pericarditis secondary to myocardial infarction. Surgical care].

The authors report the case of anteroseptal myocardial infarction, complicated by a late pericardial reaction (5th - 10th week), the development of an aneurysm, and, above all, refractory ascites (12th week) found to be secondary to constrictive pericarditis. Pericardectomy and partial resection of the aneurysm were performed. Constrictive pericarditis is rare after myocardial infarction and its relationship to a forme fruste of Dressler's syndrome remains uncertain. The pathogenesis of the constriction is unknown. This complication (only reported once previously) should be recognised because of the surgical management it implies.

Adult↗
PubMed1980

[Papaverine hepatitis].

Explore the source record for details and available documents.

Chemical and Drug Induced Liver Injury↗