Search PubMed⌕ Search

Biomedical subjects

M Choudhury

Publications and source records attributed to M Choudhury.

58 records · Page 4Linked to original sources
PubMedDate not supplied

Malakoplakia of bone. A case report.

BACKGROUND: Malakoplakia is an uncommon but distinctive granulomatous disease, characterized by an accumulation of histiocytes or Von Hansemann cells containing intracytoplasmic, laminated Michaelis-Gutmann bodies. CASE: A 3-year-old male presented with a tender swelling in the left gluteal region that had been present for one month. Smears made from a fine needle aspirate showed large histiocytic cells containing intracytoplasmic, basophilic, laminated, targetoid Michaelis-Gutmann bodies resembling Von Hansemann cells in malakoplakia. Histopathology confirmed the diagnosis of malakoplakia of bone. CONCLUSION: This case, histologically proven to be malakoplakia, demonstrated regression of the lesion following therapy. The characteristic cytologic features and presence of Von Hansemann cells may in themselves be diagnostic and obviate the need for biopsy.

Biopsy, Needle↗
PubMedDate not supplied

Localized tenosynovial giant cell tumor of tendon sheath. A case report.

BACKGROUND: Localized tenosynovial giant cell tumor of tendon sheath (TGCT-L) is a benign, slowly growing lesion with a peak incidence in the third to fifth decade of life. It is thought to arise from the synovium of tendon sheaths, frequently affecting interphalangeal joints of the hands, feet, ankles and knees. Although the histopathologic appearances are well established, only a few reports describe the cytomorphology of this lesion. CASE: A 37-year-old female presented with a slowly growing, nontender mass located near the left ankle joint. The cytologic features of localized tenosynovial giant cell tumor of tendon sheath (TGCT-L) include abundant mononuclear histiocytic cells occurring singly and in three-dimensional tissue fragments, hemosiderin within histiocytes and a few multinucleated giant cells. Subsequently, the histopathologic examination of the surgical specimen was proven to be TGCT-L. CONCLUSION: Fine needle aspiration cytology can be used as a diagnostic tool for early and accurate detection of TGCT-L since the cytologic features combined with clinical details are sufficiently distinctive.

Adult↗
PubMedDate not supplied

Mast cells and idiopathic male infertility.

Eighty-three testicular biopsies, done for evaluation of oligozoospermia and azoospermia, were reviewed. Biopsies from eight healthy fertile males served as control. Johnsen's scoring was used for the staging of spermatogenesis. The number of mast cells was counted in a 1-mm2 area to study the relationship of spermatogenesis and mast cell proliferation. An impairment of spermatogenesis was noticed as the mast cell density increased. When the Johnsen score ranged between 1 and 4, mast cells were 24 to 112, with a mean of 57.7 cells/mm2. This value was highly significant when compared with control cases (P less than .001).

Adult↗