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Biomedical subjects

M Cecchettin

Publications and source records attributed to M Cecchettin.

47 records · Page 3Linked to original sources

Effects of the composition and caloric value of infant formulas on intake and hormone levels.

Seventy-six normal full-term infants have been observed from birth to the fourth month of life. Thirty-six were breast-fed; the others were fed four different feeds (conventional or adapted formulas) containing different amounts of calories, protein, fat, and carbohydrate. The control mechanism of volume intake appears to be well functioning in infants fed human milk and adapted formulas providing conventional calorie concentrations. The other formulas were associated with either a high BUN or high base insulin concentrations. It is concluded that uncontrolled amounts of milk should be fed only to breast-fed infants and those receiving adapted formulas but not to those fed formulas that provide high calorie or protein concentrations.

Animals↗

Pepsinogen gastrin mesor ratio: a potential simple marker for gastric secretory function.

As compared to control subjects, patients with duodenal ulcer show decreased levels of serum G and increased levels of serum Group I pepsinogen (PGI). On the other hand, pregnant women in their third trimester show an increased level of serum G and decreased levels of serum PGI. Gastrin stimulates gastric secretion and has a trophic effect on the parietal cells. Concentrations of PGI in serum reflect the capacity of pepsin-secreting cells which are, in turn, closely related to the parietal cell mass. Pepsinogen/G ratio (PGI/G) could represent the effective acid-peptic secretory capacity. This study suggests that for screening and clinical purposes PGI/G ratio provides a good potentially discriminatory marker of gastric secreting capacity reliably correlating and improving the diagnostic significance of single G and/or PGI serum levels.

Adolescent↗

Toward a medical prolepsis by chronobiology.

Medicine today strongly aims at prevention and optimization of diagnosis and therapy Studies tried staging and standardization of clinical trials in diseases and made search of markers for early diagnosis, prognosis and therapy. Moreover, risk factors and other variables such as predictors are now investigated more often in groups or populations of apparently healthy subjects, especially for such diseases as atherosclerosis and neoplasia. This new aspect of increasing interest may be defined as medical prolepsis (from the Greek pi rho ómicron lambda eta psi iota zeta = anticipated idea). It includes early signals of disease (protopathology) as well as other signals the host shows as defence or alarm reaction. Hence, we suggest a chronobiological approach in this field, which allows to quantify health and reveals more subtle differences in many physiological variables. According to these views, we reported studies concerning humoral markers and other parameters considered as risk factors both in atherosclerosis and in some endocrine tumors.

Arteriosclerosis↗