We report results of a preliminary molecular dynamics study of a 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) bilayer at low hydration (5% in weight). Our results suggest a gel phase structure where the oleic chain is bent recalling the crystalline oleic acid structure. We have also found a discontinuity in the volume/temperature curve which might be related to the gel to liquid crystal phase transition in POPC.

1,2-Dipalmitoylphosphatidylcholine↗

PubMedDate not supplied

[Hypertrophic pyloric stenosis in infants. A retrospective study of cases observed in the years 1970-1990].

Although the definitive cause of infantile hypertrophic pyloric stenosis is unknown, it's probable that several predisposing risk factors would be associated with the condition. We analysed some perinatal factors in relation to the incidence of infantile hypertrophic pyloric stenosis among children observed during the period 1970-90. We examined 61 infants with surgically confirmed hypertrophic pyloric stenosis and, as controls, 61 healty children comparable for age. In every child we studied: sex, birth rank, pregnancy and delivery, birthweight, parental age, type of feeding, familial history of hypertrophic pyloric stenosis and of atopy, seasonal variation in incidence, AB0 and Rh blood phenotypes. In the 61 infants with hypertrophic pyloric stenosis, the incidence of three factors (male sex, primogeniture and feeding with artificial milk) was significantly higher than that in the controls. We conclude that infantile hypertrophic pyloric stenosis probably has a particular genetic basis, but perinatal factors are responsible for the rising of the condition. However the true aetiology remains to be elucidated.

ABO Blood-Group System↗

PubMedDate not supplied

[Celiac disease and autoimmunity].

Immune mechanisms have been invoked to explain coeliac disease and associations between this and other immunologically mediated diseases have been described. A direct relationship proposed is that coeliac disease may be associated with a range of autoimmune disease through the formation of immune complexes in the small intestine. It's more probable a common origin in an inherited predisposition to hypersensitive immuno responses to extrinsic antigens or auto-antigens. The association between coeliac disease and particular histocompatibility antigens was recognised.

Autoantibodies↗

PubMedDate not supplied

[The epidemiology of celiac disease in the provinces of Pisa, Lucca and Livorno].

Explore the source record for details and available documents.

Antibodies↗

PubMedDate not supplied

[Anti-beta-lactoglobulin antibodies as an index of increased intestinal permeability in celiac disease].

IgG antibodies to beta-lactoglobulin (ABLG) were assayed in children with coeliac disease (20 at gluten-containing diet and 35 at gluten-free diet) and in 28 "gastrointestinal" controls. Pathologic levels of ABLG were found in 16 patients with active coeliac disease (80%). In these patients the ABLG mean value was significantly higher than that found in the controls (p less than 0.001). In coeliac subjects at gluten-free diet, normal levels of ABLG were found after 6 months of diet. The presence of ABLG in the majority of untreated coeliac patients may reflect an increased permeability of the intestinal mucosa during the active stage of the disease.

Adolescent↗